4H61
 
 | | Structure of the Schizosaccharomyces pombe Mediator subunit Med6 | | Descriptor: | Mediator of RNA polymerase II transcription subunit 6 | | Authors: | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | | Deposit date: | 2012-09-19 | | Release date: | 2012-10-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of the Mediator head module.
Nature, 492, 2012
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4H63
 | | Structure of the Schizosaccharomyces pombe Mediator head module | | Descriptor: | Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... | | Authors: | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | | Deposit date: | 2012-09-19 | | Release date: | 2012-10-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structure of the Mediator head module.
Nature, 492, 2012
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4H62
 | | Structure of the Saccharomyces cerevisiae Mediator subcomplex Med17C/Med11C/Med22C | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ... | | Authors: | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | | Deposit date: | 2012-09-19 | | Release date: | 2012-10-31 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the Mediator head module.
Nature, 492, 2012
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3C0T
 | | Structure of the Schizosaccharomyces pombe Mediator subcomplex Med8C/18 | | Descriptor: | Mediator of RNA polymerase II transcription subunit 18, Mediator of RNA polymerase II transcription subunit 8 | | Authors: | Lariviere, L, Seizl, M, van Wageningen, S, Roether, S, van de Pasch, L, Feldmann, H, Straesser, K, Hahn, S, Holstege, C.P, Cramer, P. | | Deposit date: | 2008-01-21 | | Release date: | 2008-04-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure-system correlation identifies a gene regulatory Mediator submodule
Genes Dev., 22, 2008
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1SXQ
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1SXP
 | | BGT in complex with a 13mer DNA containing a central A:G mismatch | | Descriptor: | 5'-D(*A*AP*TP*AP*CP*TP*AP*AP*GP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*T)-3', DNA beta-glucosyltransferase, ... | | Authors: | Lariviere, L, Morera, S. | | Deposit date: | 2004-03-31 | | Release date: | 2004-06-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural evidence of a passive base flipping mechanism for {beta}-Glucosyltransferase
J.Biol.Chem., 279, 2004
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2HZS
 | | Structure of the Mediator head submodule Med8C/18/20 | | Descriptor: | RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8 | | Authors: | Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. | | Deposit date: | 2006-08-09 | | Release date: | 2006-09-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
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1NVK
 | | T4 phage BGT in complex with UDP and a Mn2+ ion at 1.8 A resolution | | Descriptor: | DNA beta-glucosyltransferase, GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Lariviere, L, Kurzeck, J, Gueguen-Chaignon, V, Rueger, W, Morera, S. | | Deposit date: | 2003-02-04 | | Release date: | 2003-09-09 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism
J.Mol.Biol., 330, 2003
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1NZF
 | | T4 phage BGT-D100A mutant in complex with UDP-glucose: Form II | | Descriptor: | CHLORIDE ION, DNA beta-glycosyltransferase, GLYCEROL, ... | | Authors: | Lariviere, L, Morera, S. | | Deposit date: | 2003-02-17 | | Release date: | 2003-09-09 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with
UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism.
J.Mol.Biol., 330, 2003
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1IXY
 | | Ternary complex of T4 phage BGT with UDP and a 13 mer DNA duplex | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*C)-3', 5'-D(*GP*AP*TP*AP*CP*TP*3DRP*AP*GP*AP*TP*AP*G)-3', ... | | Authors: | Lariviere, L, Morera, S. | | Deposit date: | 2002-07-09 | | Release date: | 2002-12-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Base-flipping Mechanism for the T4 Phage beta-Glucosyltransferase and Identification of a
Transition-state Analog
J.Mol.Biol., 324, 2002
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1M5R
 | | Ternary complex of T4 phage BGT with UDP and a 13 mer DNA duplex | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*C)-3', ... | | Authors: | Lariviere, L, Morera, S. | | Deposit date: | 2002-07-10 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Base-flipping mechanism for the T4 phage beta-glucosyltransferase and
identification of a transition state analog
J.Mol.Biol., 324, 2002
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1XV5
 | | alpha-glucosyltransferase (AGT) in complex with UDP | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA alpha-glucosyltransferase, ... | | Authors: | Lariviere, L, Sommer, N, Morera, S. | | Deposit date: | 2004-10-27 | | Release date: | 2005-08-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase.
J.Mol.Biol., 352, 2005
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1YA6
 | | alpha-glucosyltransferase in complex with UDP and a 13-mer DNA containing a central A:G mismatch | | Descriptor: | 5'-D(*AP*TP*AP*CP*TP*AP*AP*GP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*T)-3', COBALT HEXAMMINE(III), ... | | Authors: | Lariviere, L, Sommer, N, Morera, S. | | Deposit date: | 2004-12-17 | | Release date: | 2005-08-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase.
J.Mol.Biol., 352, 2005
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1Y6G
 | | alpha-glucosyltransferase in complex with UDP and a 13_mer DNA containing a HMU base at 2.8 A resolution | | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*T)-3', 5'-D(*GP*AP*TP*AP*CP*TP*(5HU)P*AP*GP*AP*TP*AP*G)-3', ... | | Authors: | Lariviere, L, Sommer, N, Morera, S. | | Deposit date: | 2004-12-06 | | Release date: | 2005-08-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase.
J.Mol.Biol., 352, 2005
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1Y6F
 | | alpha-glucosyltransferase in complex with UDP-glucose and DNA containing an abasic site | | Descriptor: | 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*C)-3', 5'-D(*GP*AP*TP*AP*CP*TP*(3DR)P*AP*GP*AP*TP*AP*G)-3', DI(HYDROXYETHYL)ETHER, ... | | Authors: | Lariviere, L, Sommer, N, Morera, S. | | Deposit date: | 2004-12-06 | | Release date: | 2005-08-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase.
J.Mol.Biol., 352, 2005
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1Y8Z
 | | alpha-glucosyltransferase in complex with UDP and a 13-mer DNA containing a HMU base at 1.9 A resolution | | Descriptor: | 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*G)-3', 5'-D(*GP*AP*TP*AP*CP*TP*(5HU)P*AP*GP*AP*TP*AP*G)-3', CHLORIDE ION, ... | | Authors: | Lariviere, L, Sommer, N, Morera, S. | | Deposit date: | 2004-12-14 | | Release date: | 2005-08-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase.
J.Mol.Biol., 352, 2005
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2HZM
 | | Structure of the Mediator head subcomplex Med18/20 | | Descriptor: | PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20 | | Authors: | Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. | | Deposit date: | 2006-08-09 | | Release date: | 2006-09-12 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
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1J39
 | | Crystal Structure of T4 phage BGT in complex with its UDP-glucose substrate | | Descriptor: | DNA beta-glucosyltransferase, GLYCEROL, URIDINE-5'-DIPHOSPHATE-GLUCOSE | | Authors: | Lariviere, L, Morera, S. | | Deposit date: | 2003-01-21 | | Release date: | 2003-08-19 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism.
J.Mol.Biol., 330, 2003
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1NZD
 | | T4 phage BGT-D100A mutant in complex with UDP-glucose: Form I | | Descriptor: | CHLORIDE ION, DNA beta-glycosyltransferase, GLYCEROL, ... | | Authors: | Lariviere, L, Morera, S. | | Deposit date: | 2003-02-17 | | Release date: | 2003-09-09 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism
J.Mol.Biol., 330, 2003
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4V1O
 | | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | | Deposit date: | 2014-09-29 | | Release date: | 2015-02-04 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (9.7 Å) | | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
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4V1N
 | | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | | Deposit date: | 2014-09-29 | | Release date: | 2015-02-04 | | Last modified: | 2019-04-10 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
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4V1M
 | | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | | Descriptor: | 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ... | | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | | Deposit date: | 2014-09-29 | | Release date: | 2015-02-04 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
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2XNF
 | | The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains | | Descriptor: | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 | | Authors: | Vojnic, E, Mourao, A, Seizl, M, Simon, B, Wenzeck, L, Lariviere, L, Baumli, S, Meisterernst, M, Sattler, M, Cramer, P. | | Deposit date: | 2010-08-02 | | Release date: | 2011-03-09 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structure and Vp16 Binding of the Mediator Med25 Activator Interaction Domain.
Nat.Struct.Mol.Biol., 18, 2011
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2AK7
 | | structure of a dimeric P-Ser-Crh | | Descriptor: | HPr-like protein crh, SULFATE ION | | Authors: | Chaptal, V, Gueguen-Chaignon, V, Poncet, S, Lecampion, C, Lariviere, L, Meyer, P, Galinier, A, Deutscher, J, Nessler, S, Morera, S. | | Deposit date: | 2005-08-03 | | Release date: | 2006-06-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray structure of a domain-swapped dimer of Ser46-phosphorylated Crh from Bacillus subtilis.
Proteins, 63, 2006
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3R84
 | | Structure of the Mediator head subcomplex Med11/22 | | Descriptor: | Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 22 | | Authors: | Seizl, M, Lariviere, L, Pfaffenender, T, Wenzeck, L, Cramer, P. | | Deposit date: | 2011-03-23 | | Release date: | 2011-04-27 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization.
Nucleic Acids Res., 39, 2011
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