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1E96
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BU of 1e96 by Molmil
Structure of the Rac/p67phox complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ...
Authors:Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K.
Deposit date:2000-10-10
Release date:2000-11-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the TPR domain of p67phox in complex with Rac.GTP.
Mol.Cell, 6, 2000
5TKY
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BU of 5tky by Molmil
Crystal structure of the co-translational Hsp70 chaperone Ssb in the ATP-bound, open conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein
Authors:Gumiero, A, Gese, G.V, Weyer, F.A, Lapouge, K, Sinning, I.
Deposit date:2016-10-10
Release date:2016-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain.
Nat Commun, 7, 2016
1NG2
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BU of 1ng2 by Molmil
Structure of autoinhibited p47phox
Descriptor: Neutrophil cytosolic factor 1
Authors:Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K.
Deposit date:2002-12-16
Release date:2003-05-20
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
1OV3
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BU of 1ov3 by Molmil
Structure of the p22phox-p47phox complex
Descriptor: Flavocytochrome b558 alpha polypeptide, Neutrophil cytosol factor 1
Authors:Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K.
Deposit date:2003-03-25
Release date:2003-05-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
2JPP
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BU of 2jpp by Molmil
Structural basis of RsmA/CsrA RNA recognition: Structure of RsmE bound to the Shine-Dalgarno sequence of hcnA mRNA
Descriptor: RNA (5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*CP*GP*GP*AP*UP*GP*AP*AP*GP*CP*CP*C)-3'), Translational repressor
Authors:Schubert, M, Lapouge, K, Duss, O, Oberstrass, F.C, Jelesarov, I, Haas, D, Allain, F.H.-T.
Deposit date:2007-05-21
Release date:2007-08-21
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA
Nat.Struct.Mol.Biol., 14, 2007
6Y31
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BU of 6y31 by Molmil
NG domain of human SRP54 T117 deletion mutant
Descriptor: Signal recognition particle 54 kDa protein
Authors:Juaire, K.D, Lapouge, K, Becker, M.M.M, Kotova, I, Haas, M, Carapito, R, Wild, K, Bahram, S, Sinning, I.
Deposit date:2020-02-17
Release date:2020-09-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
6SR6
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BU of 6sr6 by Molmil
Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ...
Authors:Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I.
Deposit date:2019-09-05
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Nat Commun, 11, 2020
6TGX
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BU of 6tgx by Molmil
Crystal structure of Arabidopsis thaliana NAA60 in complex with a bisubstrate analogue
Descriptor: Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA
Authors:Layer, D, Kopp, J, Lapouge, K, Sinning, I.
Deposit date:2019-11-18
Release date:2020-06-24
Last modified:2020-12-16
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response.
New Phytol., 228, 2020
6TH0
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BU of 6th0 by Molmil
Crystal structure of Arabidopsis thaliana NAA60 in complex with acetyl-CoA
Descriptor: ACETYL COENZYME *A, Acyl-CoA N-acyltransferases (NAT) superfamily protein
Authors:Layer, D, Kopp, J, Lapouge, K, Sinning, I.
Deposit date:2019-11-18
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response.
New Phytol., 228, 2020
6Z00
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BU of 6z00 by Molmil
Arabidopsis thaliana Naa50 in complex with bisubstrate analogue CoA-Ac-MVNAL
Descriptor: Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA-LEU
Authors:Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I.
Deposit date:2020-05-07
Release date:2020-12-30
Last modified:2021-05-19
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structural and functional characterization of the N-terminal acetyltransferase Naa50.
Structure, 29, 2021
6YZZ
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BU of 6yzz by Molmil
Arabidopsis thaliana Naa50 in complex with AcCoA
Descriptor: ACETYL COENZYME *A, N-alpha-acetyltransferase 50
Authors:Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I.
Deposit date:2020-05-07
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural and functional characterization of the N-terminal acetyltransferase Naa50.
Structure, 29, 2021
5MB9
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BU of 5mb9 by Molmil
Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Gumiero, A, Weyer, F.A, Valentin Gese, G, Lapouge, K, Sinning, I.
Deposit date:2016-11-07
Release date:2016-12-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex.
Nat. Struct. Mol. Biol., 24, 2017
5NIY
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BU of 5niy by Molmil
Signal recognition particle-docking protein FtsY
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Signal recognition particle-docking protein FtsY
Authors:Kempf, G, Stjepanovic, G, Lapouge, K, Sinning, I.
Deposit date:2017-03-27
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane.
Structure, 26, 2018
7Z3N
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BU of 7z3n by Molmil
Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-1 conformation
Descriptor: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
Authors:Kisonaite, M, Wild, K, Sinning, I.
Deposit date:2022-03-02
Release date:2023-04-12
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
7Z3O
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BU of 7z3o by Molmil
Cryo-EM structure of the ribosome-associated RAC complex on the 80S ribosome - RAC-2 conformation
Descriptor: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
Authors:Kisonaite, M, Wild, K, Sinning, I.
Deposit date:2022-03-02
Release date:2023-04-12
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural inventory of cotranslational protein folding by the eukaryotic RAC complex.
Nat.Struct.Mol.Biol., 30, 2023
7OLC
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BU of 7olc by Molmil
Thermophilic eukaryotic 80S ribosome at idle POST state
Descriptor: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
Authors:Kisonaite, M, Wild, K, Sinning, I.
Deposit date:2021-05-19
Release date:2022-01-26
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
7OLD
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BU of 7old by Molmil
Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state
Descriptor: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ...
Authors:Kisonaite, M, Wild, K, Sinning, I.
Deposit date:2021-05-19
Release date:2022-01-26
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
6SXO
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BU of 6sxo by Molmil
Cryo-EM structure of the human Ebp1-ribosome complex
Descriptor: 28S ribosomal RNA including ES27L-B (2839-3265), 5.8S ribosomal RNA, 60S ribosomal protein L19, ...
Authors:Wild, K, Aleksic, M, Pfeffer, M, Sinning, I.
Deposit date:2019-09-26
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments.
Nat Commun, 11, 2020
6Y32
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BU of 6y32 by Molmil
Structure of the GTPase heterodimer of human SRP54 and SRalpha
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SULFATE ION, ...
Authors:Juaire, K.D, Becker, M.M.M, Wild, K, Sinning, I.
Deposit date:2020-02-17
Release date:2020-09-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
6Y2Z
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BU of 6y2z by Molmil
NG domain of human SRP54
Descriptor: MAGNESIUM ION, PHOSPHATE ION, Signal recognition particle 54 kDa protein
Authors:Juaire, K.D, Wild, K, Sinning, I.
Deposit date:2020-02-17
Release date:2020-09-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
6Y30
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BU of 6y30 by Molmil
NG domain of human SRP54 T115A mutant
Descriptor: Signal recognition particle 54 kDa protein
Authors:Juaire, K.D, Wild, K, Sinning, I.
Deposit date:2020-02-17
Release date:2020-09-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
5M72
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BU of 5m72 by Molmil
Structure of the human SRP68-72 protein-binding domain complex
Descriptor: GLYCEROL, POTASSIUM ION, SULFATE ION, ...
Authors:Becker, M.M.M, Wild, K, Sinning, I.
Deposit date:2016-10-26
Release date:2016-12-07
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
5M73
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BU of 5m73 by Molmil
Structure of the human SRP S domain with SRP72 RNA-binding domain
Descriptor: GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ...
Authors:Becker, M.M.M, Wild, K, Sinning, I.
Deposit date:2016-10-26
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
7BJS
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BU of 7bjs by Molmil
Crystal structure of Khc/atypical Tm1 complex
Descriptor: Kinesin heavy chain, SD21996p
Authors:Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J.
Deposit date:2021-01-14
Release date:2021-05-26
Last modified:2021-07-14
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021
7BJN
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BU of 7bjn by Molmil
Crystal structure of atypical Tm1 (Tm1-I/C), residues 270-334
Descriptor: SD21996p
Authors:Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J.
Deposit date:2021-01-14
Release date:2021-05-26
Last modified:2021-07-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021

 

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