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3ZTN
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STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ.
Descriptor:HAEMAGGLUTININ, FI6V3 ANTIBODY LIGHT CHAIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Hubbard, P.A., Ritchie, A.J., Corti, D., Voss, J.E., Gamblin, S.J., Codoni, G., Macagno, A., Jarrossay, D., Pinna, D., Minola, A., Vanzetta, F., Silacci, C., Fernandez-Rodriguez, B.M., Agatic, G., Giacchetto-Sasselli, I., Vachieri, S.G., Sallusto, F., Collins, P.J., Haire, L.F., Temperton, N., Langedijk, J.P.M., Skehel, J.J., Lanzavecchia, A.
Deposit date:2011-07-12
Release date:2011-08-10
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
1BRV
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SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES
Descriptor:PROTEIN G
Authors:Doreleijers, J.F., Langedijk, J.P.M., Hard, K., Rullmann, J.A.C., Boelens, R., Schaaper, W.M., Van Oirschot, J.T., Kaptein, R.
Deposit date:1996-03-29
Release date:1997-06-05
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the immunodominant region of protein G of bovine respiratory syncytial virus.
Biochemistry, 35, 1996
5C69
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT PR-DM
Descriptor:Fusion glycoprotein F0,Fibritin, SULFATE ION, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ...
Authors:McLellan, J.S., Langedijk, J.P.M.
Deposit date:2015-06-22
Release date:2015-09-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism.
Nat Commun, 6, 2015
5C6B
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT SC-TM
Descriptor:Fusion glycoprotein F0,Fibritin, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ...
Authors:McLellan, J.S., Langedijk, J.P.M.
Deposit date:2015-06-22
Release date:2015-09-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism.
Nat Commun, 6, 2015
2XRA
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CRYSTAL STRUCTURE OF THE HK20 FAB IN COMPLEX WITH A GP41 MIMETIC 5- HELIX
Descriptor:TRANSMEMBRANE PROTEIN GP41, HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, ...
Authors:Sabin, C., Corti, D., Buzon, V., Seaman, M.S., Lutje Hulsik, D., Hinz, A., Vanzetta, F., Agatic, G., Silacci, C., Langedijk, J.P.M., Mainetti, L., Scarlatti, G., Sallusto, F., Weiss, R., Lanzavecchia, A., Weissenhorn, W.
Deposit date:2010-09-13
Release date:2010-12-15
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
PLoS Pathog., 6, 2010
3ZTJ
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STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H3 INFLUENZA HAEMAGGLUTININ.
Descriptor:HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, FI6V3 ANTIBODY HEAVY CHAIN, ...
Authors:Voss, J.E., Vachieri, S.G., Gamblin, S.J., Collins, P.J., Haire, L.F., Skehel, J.J.
Deposit date:2011-07-08
Release date:2011-08-10
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
6CK9
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CRYSTAL STRUCTURE OF HIV-1 CONC_BASE0 PREFUSION ENV TRIMER IN COMPLEX WITH HUMAN ANTIBODY FRAGMENT 3H109L AND 35O22 VARIANTS AT 3.5 ANGSTROM
Descriptor:gp41 ectodomain of Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
Authors:Lai, Y.-T., Kwong, P.D.
Deposit date:2018-02-27
Release date:2018-04-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.714 Å)
Cite:A Universal Approach to Optimize the Folding and Stability of Prefusion-Closed HIV-1 Envelope Trimers.
Cell Rep, 23, 2018
6OE4
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PREFUSION RSV F MONOMER BOUND BY NEUTRALIZING ANTIBODY CR9501
Descriptor:Fusion glycoprotein F0, CR9501 Fab Light Chain, CR9501 Fab Heavy Chain, ...
Authors:McLellan, J.S., Gilman, M.S.A.
Deposit date:2019-03-27
Release date:2019-04-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Transient Opening of Trimeric Prefusion RSV F Proteins
Nat Commun, 2019
6OE5
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SPLAYED OPEN PREFUSION RSV F CAPTURED BY CR9501 AND MOTAVIZUMAB FABS
Descriptor:Fusion glycoprotein F0,Fibritin, Motavizumab Fab Heavy Chain, Motavizumab Fab Light Chain, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2019-03-27
Release date:2019-04-17
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Transient Opening of Trimeric Prefusion RSV F Proteins
Nat Commun, 2019