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8E4F
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BU of 8e4f by Molmil
Crystal structure of dihydrofolate reductase (DHFR) from the filarial nematode W. bancrofti in complex with NADPH and folate
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Lange, K, Frey, K.M, Goodey, N.M.
Deposit date:2022-08-18
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystal structure of dihydrofolate reductase from the filarial nematode W. bancrofti in complex with NADPH and folate.
Plos Negl Trop Dis, 17, 2023
4V5K
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BU of 4v5k by Molmil
Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ng, C.L, Lang, K, Meenan, N.A.G, Sharma, A, Kelley, A.C, Kleanthous, C, Ramakrishnan, V.
Deposit date:2010-05-29
Release date:2014-07-09
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3.
Nat.Struct.Mol.Biol., 17, 2010
1BOE
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BU of 1boe by Molmil
STRUCTURE OF THE IGF BINDING DOMAIN OF THE INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-5 (IGFBP-5): IMPLICATIONS FOR IGF AND IGF-I RECEPTOR INTERACTIONS
Descriptor: PROTEIN (INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-5 (IGFBP-5))
Authors:Kalus, W, Zweckstetter, M, Renner, C, Sanchez, Y, Georgescu, J, Grol, M, Demuth, D, Schumacherdony, C, Lang, K, Holak, T.H.
Deposit date:1998-07-30
Release date:1998-12-16
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions.
EMBO J., 17, 1998
5O74
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BU of 5o74 by Molmil
Crystal structure of human Rab1b covalently bound to the GEF domain of DrrA/SidM from Legionella pneumophila in the presence of GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Multifunctional virulence effector protein DrrA, Ras-related protein Rab-1B
Authors:Cigler, M, Mueller, T, Horn-Ghetko, D, von Wrisberg, M.K, Fottner, M, Goody, R.S, Itzen, A, Mueller, M.P, Lang, K.
Deposit date:2017-06-08
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo.
Angew. Chem. Int. Ed. Engl., 56, 2017
1I16
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BU of 1i16 by Molmil
STRUCTURE OF INTERLEUKIN 16: IMPLICATIONS FOR FUNCTION, NMR, 20 STRUCTURES
Descriptor: INTERLEUKIN 16
Authors:Muehlhahn, P, Zweckstetter, M, Georgescu, J, Ciosto, C, Renner, C, Lanzendoerfer, M, Lang, K, Ambrosius, D, Baier, M, Kurth, R, Holak, T.A.
Deposit date:1998-05-20
Release date:1999-05-25
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site.
Nat.Struct.Biol., 5, 1998
1WQJ
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BU of 1wqj by Molmil
Structural Basis for the Regulation of Insulin-Like Growth Factors (IGFs) by IGF Binding Proteins (IGFBPs)
Descriptor: Insulin-like growth factor IB, Insulin-like growth factor binding protein 4
Authors:Siwanowicz, I, Popowicz, G.M, Wisniewska, M, Huber, R, Kuenkele, K.P, Lang, K, Engh, R.A, Holak, T.A.
Deposit date:2004-09-29
Release date:2005-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for the regulation of insulin-like growth factors by IGF binding proteins
Structure, 13, 2005
4AQY
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BU of 4aqy by Molmil
Structure of ribosome-apramycin complexes
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Matt, T, Ng, C.L, Lang, K, Sha, S.H, Akbergenov, R, Shcherbakov, D, Meyer, M, Duscha, S, Xie, J, Dubbaka, S.R, Perez-Fernandez, D, Vasella, A, Ramakrishnan, V, Schacht, J, Bottger, E.C.
Deposit date:2012-04-20
Release date:2012-07-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin.
Proc.Natl.Acad.Sci.USA, 109, 2012
4B3R
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BU of 4b3r by Molmil
Crystal structure of the 30S ribosome in complex with compound 30
Descriptor: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-4,6-O-[(1R)-3-phenylpropylidene]-alpha-D-glucopyranoside, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C.
Deposit date:2012-07-26
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
3C3Z
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BU of 3c3z by Molmil
Crystal structure of HIV-1 subtype F DIS extended duplex RNA bound to ribostamycin
Descriptor: HIV-1 subtype F genomic RNA, RIBOSTAMYCIN
Authors:Freisz, S, Lang, K, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
4B3S
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BU of 4b3s by Molmil
Crystal structure of the 30S ribosome in complex with compound 37
Descriptor: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-4-O-benzyl-2-deoxy-alpha-D-glucopyranoside, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C.
Deposit date:2012-07-26
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4B3M
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BU of 4b3m by Molmil
Crystal structure of the 30S ribosome in complex with compound 1
Descriptor: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-4,6-O-benzylidene-2-deoxy-alpha-D-glucopyranoside, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C.
Deposit date:2012-07-25
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
3C5D
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BU of 3c5d by Molmil
Crystal structure of HIV-1 subtype F DIS extended duplex RNA bound to lividomycin
Descriptor: 'HIV-1 subtype F genomic RNA, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, POTASSIUM ION
Authors:Freisz, S, Lang, K, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-01-31
Release date:2008-05-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
4B3T
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BU of 4b3t by Molmil
Crystal structure of the 30S ribosome in complex with compound 39
Descriptor: (2S,3S,4R,5R,6R)-2-(aminomethyl)-5-azanyl-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-bis(azanyl)-2-[(2S,3R,4R,5S,6R)-3-azanyl-5-[(4-chlorophenyl)methoxy]-6-(hydroxymethyl)-4-oxidanyl-oxan-2-yl]oxy-6-oxidanyl-cyclohexyl]oxy-2-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl]oxy-oxane-3,4-diol, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C.
Deposit date:2012-07-26
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
3C7R
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BU of 3c7r by Molmil
Crystal Structure of HIV-1 subtype F DIS extended duplex RNA bound to neomycin
Descriptor: HIV-1 subtype F genomic RNA, NEOMYCIN, POTASSIUM ION
Authors:Freisz, S, Lang, K, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-02-08
Release date:2008-05-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3DW7
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BU of 3dw7 by Molmil
Crystal Structure of the Sarcin/Ricin Domain from E. COLI 23 S rRNA, U2656-SeCH3 modified
Descriptor: Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V, Rieder, U, Lang, K, Serganov, A, Schulze-Briese, C, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW6
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BU of 3dw6 by Molmil
Crystal Structure of the Sarcin/Ricin Domain from E. COLI 23 S rRNA, U2650-SECH3 modified
Descriptor: GLYCEROL, Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V, Rieder, U, Lang, K, Serganov, A, Schulze-Briese, C, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW5
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BU of 3dw5 by Molmil
Crystal Structure of the Sarcin/Ricin Domain from E. COLI 23S rRNA, U2656-OCH3 modified
Descriptor: Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V, Rieder, U, Lang, K, Serganov, A, Schulze-Briese, C, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW4
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BU of 3dw4 by Molmil
Crystal Structure of the Sarcin/Ricin Domain from E. COLI 23 S rRNA, U2650-OCH3 modified
Descriptor: GLYCEROL, Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V, Rieder, U, Lang, K, Serganov, A, Schulze-Briese, C, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DVZ
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BU of 3dvz by Molmil
Crystal Structure of the Sarcin/Ricin Domain from E. coli 23 S rRNA
Descriptor: GLYCEROL, Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V, Rieder, U, Lang, K, Serganov, A, Schulze-Briese, C, Micura, R, Dumas, P, Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
6YX5
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BU of 6yx5 by Molmil
Structure of DrrA from Legionella pneumophilia in complex with human Rab8a
Descriptor: MAGNESIUM ION, Multifunctional virulence effector protein DrrA, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Schneider, S, Du, J, von Wrisberg, M.K, Lang, K, Itzen, A.
Deposit date:2020-04-30
Release date:2020-12-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1.
Nat Commun, 12, 2021
8SS1
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BU of 8ss1 by Molmil
Structure of a bacterial death-like domain from Azospirillum sp.
Descriptor: Serine protease
Authors:Johnson, A.G, Kranzusch, P.J.
Deposit date:2023-05-08
Release date:2023-06-07
Last modified:2023-07-19
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:CARD-like domains mediate anti-phage defense in bacterial gasdermin systems.
Biorxiv, 2023
8SRZ
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BU of 8srz by Molmil
Structure of a bacterial death-like domain from Lysobacter enzymogenes
Descriptor: Probable serine protease FE772_23065
Authors:Johnson, A.G, Kranzusch, P.J.
Deposit date:2023-05-08
Release date:2023-06-07
Last modified:2023-07-19
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:CARD-like domains mediate anti-phage defense in bacterial gasdermin systems.
Biorxiv, 2023
2H1M
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BU of 2h1m by Molmil
Synthesis, Oxidation Behavior, Crystallization and Structure of 2'-Methylseleno Guanosine Containing RNAs
Descriptor: 5'-R(*GP*CP*AP*(XUG)P*AP*GP*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', SULFATE ION
Authors:Serganov, A.A.
Deposit date:2006-05-16
Release date:2006-07-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synthesis, Oxidation Behavior, Crystallization and Structure of 2'-Methylseleno Guanosine Containing RNAs.
J.Am.Chem.Soc., 128, 2006
1H59
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BU of 1h59 by Molmil
Complex of IGFBP-5 with IGF-I
Descriptor: INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5, INSULIN-LIKE GROWTH FACTOR IA
Authors:Zeslawski, W, Beisel, H.G, Kamionka, M, Kalus, W, Engh, R.A, Huber, R, Holak, T.A.
Deposit date:2001-05-21
Release date:2002-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Interaction of Insulin-Like Growth Factor-I with the N-Terminal Domain of Igfbp-5
Embo J., 20, 2001
3C44
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BU of 3c44 by Molmil
Crystal structure of HIV-1 subtype F DIS extended duplex RNA bound to paromomycin
Descriptor: CHLORIDE ION, HIV-1 subtype F genomic RNA, PAROMOMYCIN, ...
Authors:Freisz, S, Ennifar, E, Dumas, P.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008

 

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