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6AR5
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BU of 6ar5 by Molmil
Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (Duplex Only)
Descriptor: DNA, RNA
Authors:Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M.
Deposit date:2017-08-21
Release date:2017-11-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications.
Mol. Cell, 68, 2017
6AR1
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BU of 6ar1 by Molmil
Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Nat))
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ...
Authors:Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M.
Deposit date:2017-08-21
Release date:2017-11-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications.
Mol. Cell, 68, 2017
6AR3
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BU of 6ar3 by Molmil
Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Se-Met))
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ...
Authors:Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M.
Deposit date:2017-08-21
Release date:2017-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications.
Mol. Cell, 68, 2017
1Y42
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BU of 1y42 by Molmil
Crystal structure of a C-terminally truncated CYT-18 protein
Descriptor: TYROSINE, Tyrosyl-tRNA synthetase, mitochondrial
Authors:Paukstelis, P.J, Coon, R, Madabusi, L, Nowakowski, J, Monzingo, A, Robertus, J, Lambowitz, A.M.
Deposit date:2004-11-29
Release date:2005-02-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A tyrosyl-tRNA synthetase adapted to function in group I intron splicing by acquiring a new RNA binding surface.
Mol.Cell, 17, 2005
6DD5
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BU of 6dd5 by Molmil
Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein
Descriptor: GLYCEROL, MMB-1 Cas6 Fused to Maltose Binding Protein,CRISPR-associated endonuclease Cas1, SULFATE ION, ...
Authors:Stamos, J.L, Mohr, G, Silas, S, Makarova, K.S, Markham, L.M, Yao, J, Lucas-Elio, P, Sanchez-Amat, A, Fire, A.Z, Koonin, E.V, Lambowitz, A.M.
Deposit date:2018-05-09
Release date:2018-10-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition.
Mol. Cell, 72, 2018
5IHX
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BU of 5ihx by Molmil
Crystal Structure of a C-terminally truncated Aspergillus nidulans mitochondrial tyrosyl-tRNA synthetase
Descriptor: TYROSINE, Tyrosine--tRNA ligase, mitochondrial
Authors:Lamech, L.T, Lambowitz, A.M.
Deposit date:2016-02-29
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Crystal Structure of a C-terminally truncated Aspergillus nidulans mitochondrial tyrosyl-tRNA synthetase
To be published
2RKJ
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BU of 2rkj by Molmil
Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group I intron RNA
Descriptor: RNA (238-MER), RNA (5'-R(P*GP*CP*UP*U)-3'), Tyrosyl-tRNA synthetase
Authors:Paukstelis, P.J, Chen, J.-H, Chase, E, Lambowitz, A.M, Golden, B.L.
Deposit date:2007-10-16
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA.
Nature, 451, 2008
5IJX
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BU of 5ijx by Molmil
Crystal Structure of a C-terminally truncated Coccidioides posadasii mitochondrial tyrosyl-tRNA synthetase
Descriptor: TYROSINE, Tyrosine--tRNA ligase, mitochondrial
Authors:Lamech, L.T, Lambowitz, A.M.
Deposit date:2016-03-02
Release date:2016-04-06
Last modified:2020-03-04
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal Structure of a C-terminally truncated Coccidioides posadasii mitochondrial tyrosyl-tRNA synthetase
To be published
3SQX
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BU of 3sqx by Molmil
Structure of Mss116p (NTE and C-tail double deletion) bound to ssRNA and AMP-PNP
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, MAGNESIUM ION, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2011-07-06
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:High-Throughput Genetic Identification of Functionally Important Regions of the Yeast DEAD-Box Protein Mss116p.
J.Mol.Biol., 413, 2011
3SQW
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BU of 3sqw by Molmil
Structure of Mss116p (NTE deletion) bound to ssRNA and AMP-PNP
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, MAGNESIUM ION, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2011-07-06
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:High-Throughput Genetic Identification of Functionally Important Regions of the Yeast DEAD-Box Protein Mss116p.
J.Mol.Biol., 413, 2011
3I5X
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BU of 3i5x by Molmil
Structure of Mss116p bound to ssRNA and AMP-PNP
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-dependent RNA helicase MSS116, MAGNESIUM ION, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
4TYW
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BU of 4tyw by Molmil
DEAD-box helicase Mss116 bound to ssRNA and ADP-BeF
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, mitochondrial, ...
Authors:Mallam, A.L, Sidote, D.J, Lambowitz, A.M.
Deposit date:2014-07-09
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
4TZ6
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BU of 4tz6 by Molmil
DEAD-box helicase Mss116 bound to ssRNA and UDP-BeF
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Mallam, A.L, Sidote, D.J, Lambowitz, A.M.
Deposit date:2014-07-09
Release date:2015-01-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
4TZ0
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BU of 4tz0 by Molmil
DEAD-box helicase Mss116 bound to ssRNA and GDP-BeF
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Mallam, A.L, Sidote, D.J, Lambowitz, A.M.
Deposit date:2014-07-09
Release date:2014-12-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
4TYY
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BU of 4tyy by Molmil
DEAD-box helicase Mss116 bound to ssRNA and CDP-BeF
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Mallam, A.L, Sidote, D.J, Lambowitz, A.M.
Deposit date:2014-07-09
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
4TYN
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BU of 4tyn by Molmil
DEAD-box helicase Mss116 bound to ssDNA and ADP-BeF
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, mitochondrial, ...
Authors:Mallam, A.L, Sidote, D.J, Lambowitz, A.M.
Deposit date:2014-07-08
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.959 Å)
Cite:Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
3I61
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BU of 3i61 by Molmil
Structure of Mss116p bound to ssRNA and ADP-Beryllium Fluoride
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
3I62
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BU of 3i62 by Molmil
Structure of Mss116p bound to ssRNA and ADP-Aluminum Fluoride
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
3I5Y
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BU of 3i5y by Molmil
Structure of Mss116p bound to ssRNA containing a single 5-BrU and AMP-PNP
Descriptor: 5'-R(*UP*UP*UP*(5BU)P*UP*UP*UP*UP*UP*U)-3', ATP-dependent RNA helicase MSS116, MAGNESIUM ION, ...
Authors:Del Campo, M, Lambowitz, A.M.
Deposit date:2009-07-06
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA
Mol.Cell, 35, 2009
4DB2
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BU of 4db2 by Molmil
Mss116p DEAD-box helicase domain 2 bound to an RNA duplex
Descriptor: 5'-R(*GP*GP*GP*CP*GP*GP*GP*CP*CP*CP*GP*CP*CP*C)-3', ATP-dependent RNA helicase MSS116, mitochondrial
Authors:Mallam, A.L, Del Campo, M, Gilman, B.D, Sidote, D.J, Lambowitz, A.
Deposit date:2012-01-13
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p.
Nature, 490, 2012
4DB4
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BU of 4db4 by Molmil
Mss116p DEAD-box helicase domain 2 bound to a chimaeric RNA-DNA duplex
Descriptor: 5'-R(*GP*GP*GP*CP*GP*GP*G)-D(P*CP*CP*CP*GP*CP*CP*C)-3', ATP-dependent RNA helicase MSS116, mitochondrial
Authors:Mallam, A.L, Del Campo, M, Gilman, B.D, Sidote, D.J, Lambowitz, A.
Deposit date:2012-01-13
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.599 Å)
Cite:Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p.
Nature, 490, 2012
7K9Y
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BU of 7k9y by Molmil
GsI-IIC RT Template-Switching Complex (twinned)
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*CP*CP*AP*GP*GP*CP*AP*AP*C)-3'), MAGNESIUM ION, ...
Authors:Stamos, J.L, Lentzsch, A.M.
Deposit date:2020-09-29
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase.
J.Biol.Chem., 297, 2021

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