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2DJM
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BU of 2djm by Molmil
Solution structure of N-terminal starch-binding domain of glucoamylase from Rhizopus oryzae
Descriptor: glucoamylase A
Authors:Liu, Y.N, Lai, Y.T, Lyu, P.C.
Deposit date:2006-04-04
Release date:2007-03-27
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of family 21 carbohydrate-binding module from Rhizopus oryzae glucoamylase
Biochem.J., 403, 2007
5K6F
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BU of 5k6f by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant.
Descriptor: Fusion glycoprotein F0
Authors:Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
Deposit date:2016-05-24
Release date:2016-08-10
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K6C
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BU of 5k6c by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 variant.
Descriptor: Fusion glycoprotein F0,Fusion glycoprotein F0, SULFATE ION
Authors:Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
Deposit date:2016-05-24
Release date:2016-10-12
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (3.576 Å)
Cite:Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
3FWL
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BU of 3fwl by Molmil
Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli
Descriptor: MOENOMYCIN, Penicillin-binding protein 1B
Authors:Sung, M.T, Lai, Y.T, Huang, C.Y, Chou, L.Y, Wong, C.H, Ma, C.
Deposit date:2009-01-19
Release date:2009-06-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.086 Å)
Cite:Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 106, 2009
3VMA
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BU of 3vma by Molmil
Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli
Descriptor: MOENOMYCIN, Penicillin-binding protein 1B
Authors:Huang, C.Y, Sung, M.T, Lai, Y.T, Chou, L.Y, Shih, H.W, Cheng, W.C, Wong, C.H, Ma, C.
Deposit date:2011-12-09
Release date:2012-03-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.161 Å)
Cite:Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 106, 2009
4D9J
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BU of 4d9j by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains
Descriptor: Designed 16nm tetrahedral protein cage containing Non-haem bromoperoxidase BPO-A2 and Matrix protein 1
Authors:Lai, Y.-T, Cascio, D, Yeates, T.O.
Deposit date:2012-01-11
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Structure of a 16-nm cage designed by using protein oligomers.
Science, 336, 2012
4IQ4
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BU of 4iq4 by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P21212 form
Descriptor: Non-haem bromoperoxidase BPO-A2, Matrix protein 1
Authors:Lai, Y.-T, Sawaya, M.R, Yeates, T.O.
Deposit date:2013-01-10
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
J.Am.Chem.Soc., 135, 2013
4ITV
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BU of 4itv by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form
Descriptor: Non-haem bromoperoxidase BPO-A2, Matrix protein 1
Authors:Lai, Y.-T, Sawaya, M.R, Yeates, T.O.
Deposit date:2013-01-18
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.598 Å)
Cite:Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
J.Am.Chem.Soc., 135, 2013
4IVJ
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BU of 4ivj by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, I222 form
Descriptor: Non-haem bromoperoxidase BPO-A2, Matrix protein 1
Authors:Lai, Y.-T, Sawaya, M.R, Yeates, T.O.
Deposit date:2013-01-23
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.351 Å)
Cite:Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
J.Am.Chem.Soc., 135, 2013
4ZSZ
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BU of 4zsz by Molmil
Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-3.0
Descriptor: Uncharacterized Fusion Protein
Authors:Lai, Y.-T, Yeates, T.O.
Deposit date:2015-05-14
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.251 Å)
Cite:On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker.
Protein Eng.Des.Sel., 28, 2015
4ZSV
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BU of 4zsv by Molmil
Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-1.0
Descriptor: Uncharacterized protein
Authors:Lai, Y.-T, Yeates, T.O.
Deposit date:2015-05-14
Release date:2015-08-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker.
Protein Eng.Des.Sel., 28, 2015
4ZSX
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BU of 4zsx by Molmil
Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-2.0
Descriptor: PHOSPHATE ION, Uncharacterized Fusion Protein
Authors:Lai, Y.-T, Yeates, T.O.
Deposit date:2015-05-14
Release date:2015-08-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker.
Protein Eng.Des.Sel., 28, 2015
4QCC
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BU of 4qcc by Molmil
Structure of a cube-shaped, highly porous protein cage designed by fusing symmetric oligomeric domains
Descriptor: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, peptidyl-prolyl cis-trans isomerase chimera
Authors:Lai, Y.-T, Yeates, T.O.
Deposit date:2014-05-10
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (7.078 Å)
Cite:Structure of a designed protein cage that self-assembles into a highly porous cube.
Nat Chem, 6, 2014
3VDX
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BU of 3vdx by Molmil
Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains
Descriptor: Designed 16nm tetrahedral protein cage containing Non-haem bromoperoxidase BPO-A2 and Matrix protein 1
Authors:Lai, Y.-T, Cascio, D, Yeates, T.O.
Deposit date:2012-01-06
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Structure of a 16-nm cage designed by using protein oligomers.
Science, 336, 2012
6MUG
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BU of 6mug by Molmil
Crystal Structure of HIV-1 B41 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.8 Angstrom
Descriptor: 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-(4-bromo-7-fluoro-1H-indol-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2018-10-23
Release date:2019-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.954 Å)
Cite:Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MU7
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BU of 6mu7 by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-818251 in Complex with Human Antibodies 3H109L and 35O22 at 3.1 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain portion, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2018-10-22
Release date:2019-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MTJ
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BU of 6mtj by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-378806 in Complex with Human Antibodies 3H109L and 35O22 at 2.9 Angstrom
Descriptor: 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2018-10-19
Release date:2019-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.336 Å)
Cite:Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MUF
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BU of 6muf by Molmil
Crystal Structure of HIV-1 B41 SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.4 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain portion, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2018-10-23
Release date:2019-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MTN
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BU of 6mtn by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor Compound 484 in Complex with Human Antibodies 3H109L and 35O22 at 3.0 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain portion, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2018-10-20
Release date:2019-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MU8
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BU of 6mu8 by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-(4-bromo-7-fluoro-1H-indol-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2018-10-22
Release date:2019-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.993 Å)
Cite:Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MU6
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BU of 6mu6 by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-814508 in Complex with Human Antibodies 3H109L and 35O22 at 3.2 Angstrom
Descriptor: (2R)-{1-[{7-[2-({[3-(dimethylamino)propyl](methyl)amino}methyl)-1,3-thiazol-4-yl]-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl}(oxo)acetyl]piperidin-4-yl}(phenyl)acetonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2018-10-22
Release date:2019-01-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
5TDG
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BU of 5tdg by Molmil
Crystal structure of prefusion-stabilized bovine RSV F (DS-Cav1 variant: strain ATue51908)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0,Fibritin
Authors:Chen, L, Zhang, B, Kwong, P.D.
Deposit date:2016-09-19
Release date:2017-08-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Protection of calves by a prefusion-stabilized bovine RSV F vaccine.
NPJ Vaccines, 2, 2017
6VZI
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BU of 6vzi by Molmil
Crystal Structure of HIV-1 CAP256 RnS-3mut-2G-SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2020-02-28
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.716 Å)
Cite:Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J.Virol., 94, 2020
6W03
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BU of 6w03 by Molmil
Crystal Structure of HIV-1 BG505 DS-SOSIP.3mut Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.3 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2020-02-28
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J.Virol., 94, 2020
6WIX
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BU of 6wix by Molmil
Crystal Structure of HIV-1 MI369 RnS-DS.SOSIP Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lai, Y.-T, Olia, A, Kwong, P.D.
Deposit date:2020-04-10
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains.
Cell Rep, 33, 2020

 

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