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2MHB
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THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION
Descriptor:HEMOGLOBIN (AQUO MET) (ALPHA CHAIN), HEMOGLOBIN (AQUO MET) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
Authors:Ladner, R.C., Heidner, E.G., Perutz, M.F.
Deposit date:1977-02-14
Release date:1983-01-20
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of horse methaemoglobin at 2-0 A resolution.
J.Mol.Biol., 114, 1977
2ATC
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CRYSTAL AND MOLECULAR STRUCTURES OF NATIVE AND CTP-LIGANDED ASPARTATE CARBAMOYLTRANSFERASE FROM ESCHERICHIA COLI
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, REGULATORY CHAIN, ...
Authors:Honzatko, R.B., Crawford, J.L., Monaco, H.L., Ladner, J.E., Edwards, B.F.P., Evans, D.R., Warren, S.G., Wiley, D.C., Ladner, R.C., Lipscomb, W.N.
Deposit date:1982-03-24
Release date:1982-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli.
J.Mol.Biol., 160, 1982
1ACM
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ARGININE 54 IN THE ACTIVE SITE OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE IS CRITICAL FOR CATALYSIS: A SITE-SPECIFIC MUTAGENESIS, NMR AND X-RAY CRYSTALLOGRAPHY STUDY
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C., Kantrowitz, E.R., Lipscomb, W.N.
Deposit date:1992-07-08
Release date:1992-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study.
Protein Sci., 1, 1992
4AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
5AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
6AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Stevens, R.C., Gouaux, J.E., Lipscomb, W.N.
Deposit date:1990-04-26
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
7AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Stevens, R.C., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
8AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Stevens, R.C., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
1AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
2AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
3AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E., Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
8ATC
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COMPLEX OF N-PHOSPHONACETYL-L-ASPARTATE WITH ASPARTATE CARBAMOYLTRANSFERASE. X-RAY REFINEMENT, ANALYSIS OF CONFORMATIONAL CHANGES AND CATALYTIC AND ALLOSTERIC MECHANISMS
Descriptor:ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Ke, H., Lipscomb, W.N., Cho, Y., Honzatko, R.B.
Deposit date:1989-08-25
Release date:1990-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complex of N-phosphonacetyl-L-aspartate with aspartate carbamoyltransferase. X-ray refinement, analysis of conformational changes and catalytic and allosteric mechanisms.
J.Mol.Biol., 204, 1988
4OGX
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CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.4 ANGSTROM RESOLUTION
Descriptor:Plasma kallikrein, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ...
Authors:Edwards, T.E., Clifton, M.C., Abendroth, J., Nixon, A., Ladner, R.
Deposit date:2014-01-16
Release date:2014-07-09
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014
4OGY
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CRYSTAL STRUCTURE OF FAB DX-2930 IN COMPLEX WITH HUMAN PLASMA KALLIKREIN AT 2.1 ANGSTROM RESOLUTION
Descriptor:Plasma kallikrein, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ...
Authors:Edwards, T.E., Clifton, M.C., Abendroth, J., Nixon, A., Ladner, R.
Deposit date:2014-01-16
Release date:2014-07-09
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014
4PUB
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CRYSTAL STRUCTURE OF FAB DX-2930
Descriptor:DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, CHLORIDE ION
Authors:Abendroth, J., Edwards, T.E., Nixon, A., Ladner, R.
Deposit date:2014-03-12
Release date:2014-07-09
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014
1EST
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THE ATOMIC STRUCTURE OF CRYSTALLINE PORCINE PANCREATIC ELASTASE AT 2.5 ANGSTROMS RESOLUTION. COMPARISONS WITH THE STRUCTURE OF ALPHA-CHYMOTRYPSIN
Descriptor:PORCINE PANCREATIC ELASTASE, SULFATE ION, PARA-TOLUENE SULFONATE
Authors:Sawyer, L., Shotton, D.M., Watson, H.C.
Deposit date:1976-05-17
Release date:1976-05-27
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The atomic structure of crystalline porcine pancreatic elastase at 2.5 A resolution: comparisons with the structure of alpha-chymotrypsin.
J.Mol.Biol., 118, 1978
1QNJ
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THE STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT ATOMIC RESOLUTION (1.1 A)
Descriptor:ELASTASE, SODIUM ION, SULFATE ION
Authors:Wurtele, M., Hahn, M., Hilpert, K., Hohne, W.
Deposit date:1999-10-15
Release date:2000-03-31
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic Resolution Structure of Native Porcine Pancreatic Elastase at 1.1 A
Acta Crystallogr.,Sect.D, 56, 2000
1A2Q
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SUBTILISIN BPN' MUTANT 7186
Descriptor:SUBTILISIN BPN', CALCIUM ION, ACETONE
Authors:Gilliland, G.L., Whitlow, M., Howard, A.J.
Deposit date:1998-01-08
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AK9
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SUBTILISIN MUTANT 8321
Descriptor:SUBTILISIN 8321, CALCIUM ION, SODIUM ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-05-30
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AQN
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SUBTILISIN MUTANT 8324
Descriptor:SUBTILISIN 8324, CALCIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-07-31
Release date:1998-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stabilityfor subtilisin BPN' through incremental changes in the free energy of unfolding
To be published
1AU9
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SUBTILISIN BPN' MUTANT 8324 IN CITRATE
Descriptor:SUBTILISIN BPN', CALCIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-09-12
Release date:1997-12-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1BMA
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BENZYL METHYL AMINIMIDE INHIBITOR COMPLEXED TO PORCINE PANCREATIC ELASTASE
Descriptor:Chymotrypsin-like elastase family member 1, CALCIUM ION, SULFATE ION, ...
Authors:Peisach, E., Casebier, D., Gallion, S.L., Furth, P., Petsko, G.A., Hogan Jr., J.C., Ringe, D.
Deposit date:1995-05-01
Release date:1995-12-07
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interaction of a peptidomimetic aminimide inhibitor with elastase.
Science, 269, 1995
1ELA
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ANALOGOUS INHIBITORS OF ELASTASE DO NOT ALWAYS BIND ANALOGOUSLY
Descriptor:ELASTASE, 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-prolinamide, CALCIUM ION, ...
Authors:Mattos, C., Rasmussen, B., Ding, X., Petsko, G.A., Ringe, D.
Deposit date:1993-12-07
Release date:1994-04-30
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
1ELB
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ANALOGOUS INHIBITORS OF ELASTASE DO NOT ALWAYS BIND ANALOGOUSLY
Descriptor:ELASTASE, 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-leucinamide, CALCIUM ION, ...
Authors:Mattos, C., Rasmussen, B., Ding, X., Petsko, G.A., Ringe, D.
Deposit date:1993-12-07
Release date:1994-06-22
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
1ELC
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ANALOGOUS INHIBITORS OF ELASTASE DO NOT ALWAYS BIND ANALOGOUSLY
Descriptor:ELASTASE, 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-phenylalaninamide, CALCIUM ION
Authors:Mattos, C., Rasmussen, B., Ding, X., Petsko, G.A., Ringe, D.
Deposit date:1993-12-07
Release date:1994-04-30
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
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