3B43
| I-band fragment I65-I70 from titin | Descriptor: | Titin | Authors: | von Castelmur, E, Marino, M, Labeit, D, Labeit, S, Mayans, O. | Deposit date: | 2007-10-23 | Release date: | 2008-01-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain Proc.Natl.Acad.Sci.Usa, 105, 2008
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2NZI
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2RIK
| I-band fragment I67-I69 from titin | Descriptor: | Titin | Authors: | Marino, M, von Castelmur, E, Labeit, D, Labeit, S, Mayans, O. | Deposit date: | 2007-10-11 | Release date: | 2008-01-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain Proc.Natl.Acad.Sci.Usa, 105, 2008
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2RJM
| 3Ig structure of titin domains I67-I69 E-to-A mutated variant | Descriptor: | Titin | Authors: | von Castelmur, E, Marino, M, Labeit, D, Labeit, S, Mayans, O. | Deposit date: | 2007-10-15 | Release date: | 2008-01-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain Proc.Natl.Acad.Sci.Usa, 105, 2008
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4QEG
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4JNW
| Bacterially expressed Titin Kinase | Descriptor: | GLYCEROL, Titin | Authors: | Bogomolovas, J, Labeit, S, Mayans, O. | Deposit date: | 2013-03-16 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line. Open Biol, 4, 2014
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5JOE
| Crystal structure of I81 from titin | Descriptor: | 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Titin | Authors: | Fleming, J, Zhou, T, Bogomolovas, J, Labeit, S, Mayans, O. | Deposit date: | 2016-05-02 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex. Febs Lett., 590, 2016
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3DDT
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3UTO
| Twitchin kinase region from C.elegans (Fn31-NL-kin-CRD-Ig26) | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Castelmur, E, Barbieri, S, Mayans, O. | Deposit date: | 2011-11-26 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase. Proc.Natl.Acad.Sci.USA, 109, 2012
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2JNF
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6YGN
| Titin kinase and its flanking domains | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Titin | Authors: | Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O. | Deposit date: | 2020-03-27 | Release date: | 2021-04-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere. Embo Rep., 22, 2021
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5JDE
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5JDD
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5JDJ
| Crystal structure of domain I10 from titin in space group P212121 | Descriptor: | CALCIUM ION, Titin | Authors: | Williams, R, Bogomolovas, J, Labiet, S, Mayans, O. | Deposit date: | 2016-04-16 | Release date: | 2016-08-17 | Last modified: | 2016-10-12 | Method: | X-RAY DIFFRACTION (1.738 Å) | Cite: | Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I. Open Biology, 6, 2016
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8BW6
| Titin FnIII-domain I110 (I/A6) from the MIR region | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Mayans, O, Fleming, J.R. | Deposit date: | 2022-12-06 | Release date: | 2023-02-15 | Last modified: | 2023-03-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis. Biomedicines, 11, 2023
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8BVO
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8BXR
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4M3L
| Crystal Structure of the coiled coil domain of MuRF1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, E3 ubiquitin-protein ligase TRIM63, ... | Authors: | Mayans, O, Franke, B. | Deposit date: | 2013-08-06 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1. Open Biol, 4, 2014
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1TIT
| TITIN, IG REPEAT 27, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | TITIN, I27 | Authors: | Improta, S, Politou, A.S, Pastore, A. | Deposit date: | 1996-02-02 | Release date: | 1996-07-11 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Immunoglobulin-like modules from titin I-band: extensible components of muscle elasticity. Structure, 4, 1996
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1TIU
| TITIN, IG REPEAT 27, NMR, 24 STRUCTURES | Descriptor: | TITIN, I27 | Authors: | Improta, S, Politou, A.S, Pastore, A. | Deposit date: | 1996-02-02 | Release date: | 1996-07-11 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Immunoglobulin-like modules from titin I-band: extensible components of muscle elasticity. Structure, 4, 1996
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