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1I34
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SOLUTION DNA QUADRUPLEX WITH DOUBLE CHAIN REVERSAL LOOP AND TWO DIAGONAL LOOPS CONNECTING GGGG TETRADS FLANKED BY G-(T-T) TRIAD AND T-T-T TRIPLE
Descriptor:5'-D(*GP*GP*TP*TP*TP*TP*GP*GP*CP*AP*GP*GP*GP*TP*TP*TP*TP*GP*GP*T)-3'
Authors:Kuryavyi, V., Majumdar, A., Shallop, A., Chernichenko, N., Skripkin, E., Jones, R., Patel, D.J.
Deposit date:2001-02-12
Release date:2001-06-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple.
J.Mol.Biol., 310, 2001
2KPR
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MONOMERIC INTRONIC HUMAN CHL1 GENE QUADRUPLEX DNA NMR, 17 STRUCTURES
Descriptor:5'-D(*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'
Authors:Kuryavyi, V., Patel, D.J.
Deposit date:2009-10-19
Release date:2010-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence.
Structure, 18, 2010
2KYO
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DIMERIC HUMAN CKIT-2 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA NMR, 10 STRUCTURES
Descriptor:5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
Authors:Kuryavyi, V., Phan, A.T., Patel, D.J.
Deposit date:2010-06-05
Release date:2010-06-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
2KYP
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MONOMERIC HUMAN CKIT-2 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA NMR, 12 STRUCTURES
Descriptor:5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
Authors:Kuryavyi, V., Phan, A.T., Patel, D.J.
Deposit date:2010-06-06
Release date:2010-06-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
2LXV
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DIMERIC PIL-E G-QUADRUPLEX DNA FROM NEISSERIA GONORRHOEAE, NMR 11 STRUCTURES
Descriptor:5'-D(*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*GP*GP
Authors:Kuryavyi, V., Patel, D.J.
Deposit date:2012-08-31
Release date:2012-11-28
Last modified:2012-12-26
Method:SOLUTION NMR
Cite:RecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5' End-Stacked Dimeric Parallel G-Quadruplexes.
Structure, 20, 2012
1YVU
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CRYSTAL STRUCTURE OF A. AEOLICUS ARGONAUTE
Descriptor:hypothetical protein aq_1447, CALCIUM ION
Authors:Yuan, Y.R., Pei, Y., Ma, J.B., Kuryavyi, V., Zhadina, M., Meister, G., Chen, H.Y., Dauter, Z., Tuschl, T., Patel, D.J.
Deposit date:2005-02-16
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of A. aeolicus Argonaute provides unique perspectives into the mechanism of guide strand-mediated mRNA cleavage
Mol.Cell, 19, 2005
2ASD
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OXOG-MODIFIED INSERTION TERNARY COMPLEX
Descriptor:5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', 5'-D(*CP*T*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', DNA polymerase IV, ...
Authors:Rechkoblit, O., Malinina, L., Cheng, Y., Kuryavyi, V., Broyde, S., Geacintov, N.E., Patel, D.J.
Deposit date:2005-08-23
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
2ASJ
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OXOG-MODIFIED PREINSERTION BINARY COMPLEX
Descriptor:5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', 5'-D(*CP*TP*AP*AP*CP*(8OG)*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', DNA polymerase IV, ...
Authors:Rechkoblit, O., Malinina, L., Cheng, Y., Kuryavyi, V., Broyde, S., Geacintov, N.E., Patel, D.J.
Deposit date:2005-08-23
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
2ASL
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OXOG-MODIFIED POSTINSERTION BINARY COMPLEX
Descriptor:5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DOC))-3', 5'-D(*CP*T*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', DNA polymerase IV, ...
Authors:Rechkoblit, O., Malinina, L., Cheng, Y., Kuryavyi, V., Broyde, S., Geacintov, N.E., Patel, D.J.
Deposit date:2005-08-23
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
2ATL
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UNMODIFIED INSERTION TERNARY COMPLEX
Descriptor:5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', 5'-D(*CP*T*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', Dpo4 polymerase IV, ...
Authors:Rechkoblit, O., Malinina, L., Cheng, Y., Kuryavyi, V., Broyde, S., Geacintov, N.E., Patel, D.J.
Deposit date:2005-08-25
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
2AU0
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UNMODIFIED PREINSERTION BINARY COMPLEX
Descriptor:5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', 5'-D(*CP*TP*AP*AP*CP*G*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', Dpo4 polymerase IV, ...
Authors:Rechkoblit, O., Malinina, L., Cheng, Y., Kuryavyi, V., Broyde, S., Geacintov, N.E., Patel, D.J.
Deposit date:2005-08-26
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
2LA5
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RNA DUPLEX-QUADRUPLEX JUNCTION COMPLEX WITH FMRP RGG PEPTIDE
Descriptor:RNA (36-MER), Fragile X mental retardation 1 protein
Authors:Phan, A., Kuryavyi, V., Darnell, J., Serganov, A., Majumdar, A., Ilin, S., Darnell, R., Patel, D.
Deposit date:2011-03-03
Release date:2011-06-08
Last modified:2011-07-20
Method:SOLUTION NMR
Cite:Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.
Nat.Struct.Mol.Biol., 18, 2011
1D6D
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SOLUTION DNA STRUCTURE CONTAINING (A-A)-T TRIADS INTERDIGITATED BETWEEN A-T BASE PAIRS AND GGGG TETRADS; NMR, 8 STRUCT.
Descriptor:5'-D(*AP*AP*GP*GP*TP*TP*TP*TP*AP*AP*GP*G)-3'
Authors:Kuryavyi, V.V., Kettani, A., Wang, W., Jones, R., Patel, D.J.
Deposit date:1999-10-13
Release date:2000-01-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A diamond-shaped zipper-like DNA architecture containing triads sandwiched between mismatches and tetrads.
J.Mol.Biol., 295, 2000
2LXQ
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MONOMERIC PILE G-QUADRUPLEX DNA FROM NEISSERIA GONORRHOEAE
Descriptor:DNA (5'-D(*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*T)-3')
Authors:Kuryavyi, V.V., Patel, D.J.
Deposit date:2012-08-30
Release date:2012-11-28
Last modified:2012-12-26
Method:SOLUTION NMR
Cite:RecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5' End-Stacked Dimeric Parallel G-Quadruplexes.
Structure, 20, 2012
2A5P
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MONOMERIC PARALLEL-STRANDED DNA TETRAPLEX WITH SNAP-BACK 3+1 3' G-TETRAD, SINGLE-RESIDUE CHAIN REVERSAL LOOPS, GAG TRIAD IN THE CONTEXT OF GAAG DIAGONAL LOOP, NMR, 8 STRUCT.
Descriptor:5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3'
Authors:Phan, A.T., Kuryavyi, V.V., Gaw, H.Y., Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
2A5R
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COMPLEX OF TETRA-(4-N-METHYLPYRIDYL) PORPHIN WITH MONOMERIC PARALLEL-STRANDED DNA TETRAPLEX, SNAP-BACK 3+1 3' G-TETRAD, SINGLE-RESIDUE CHAIN REVERSAL LOOPS, GAG TRIAD IN THE CONTEXT OF GAAG DIAGONAL LOOP, C-MYC PROMOTER, NMR, 6 STRUCT.
Descriptor:5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3', (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin
Authors:Phan, A.T., Kuryavyi, V.V., Gaw, H.Y., Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
2JSK
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, 16 G FORM 1, NMR, 10 STRUCTURES
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-07
Release date:2008-07-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2JSL
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, FORM 2 NATURAL, NMR, 10 STRUCTURES
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-08
Release date:2008-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2JSM
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, FORM 1 NATURAL
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-09
Release date:2008-07-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution
Nucleic Acids Res., 35, 2007
2JSQ
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MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, FORM 2 15BRG, NMR, 10 STRUCTURES
Descriptor:HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V., Phan, A.T., Luu, K.N., Patel, D.J.
Deposit date:2007-07-11
Release date:2008-07-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007