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Solution NMR structure of DOT1L in complex with AF9 (DOT1L-AF9)
Descriptor:	Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-9
Authors:	Kuntimaddi, A, Bushweller, J.H.
Deposit date:	2014-09-24
Release date:	2015-04-22
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential. Cell Rep, 11, 2015

Solution NMR structure of CBX8 in complex with AF9 (CBX8-AF9)
Descriptor:	Chromobox protein homolog 8, Protein AF-9
Authors:	Kuntimaddi, A, Leach, B.I, Bushweller, J.H.
Deposit date:	2015-06-30
Release date:	2016-07-20
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Solution NMR Structure of CBX8 in complex with AF9 (CBX8-AF9) To be Published

Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9)
Descriptor:	BCL-6 corepressor, Protein AF-9
Authors:	Schmidt, C.R, Kuntimaddi, A, Leach, B.I, Bushweller, J.H.
Deposit date:	2017-10-04
Release date:	2018-10-10
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity. Blood Cancer Discov, 1, 2020

Solution structure of the AF4-AF9 complex
Descriptor:	AF4/FMR2 family member 1/Protein AF-9 chimera
Authors:	Leach, B.I, Kuntimaddi, A, Schmidt, C.R, Cierpicki, T, Johnson, S.A, Bushweller, J.H.
Deposit date:	2011-11-18
Release date:	2013-01-09
Last modified:	2013-01-30
Method:	SOLUTION NMR
Cite:	Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding. Structure, 21, 2013