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1RR7
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BU of 1rr7 by Molmil
Crystal structure of the Middle Operon Regulator protein of Bacteriophage Mu
Descriptor: Middle operon regulator, PLATINUM (II) ION
Authors:Kumaraswami, M, Howe, M.M, Park, H.W.
Deposit date:2003-12-08
Release date:2004-08-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Mor protein of bacteriophage Mu, a member of the Mor/C family of transcription activators.
J.Biol.Chem., 279, 2004
3VIB
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BU of 3vib by Molmil
Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, MtrR, PHOSPHATE ION
Authors:Kumaraswami, M, Shafer, W.M, Brennan, R.G.
Deposit date:2011-09-27
Release date:2012-10-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for multidrug recognitionand antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae
TO BE PUBLISHED
3IAO
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BU of 3iao by Molmil
Conformational plasticity of the coiled coil domain of BmrR is required for bmr promoter binding-the unliganded structure of BmrR
Descriptor: Multidrug-efflux transporter 1 regulator
Authors:Kumaraswami, M, Newberry, K.J, Brennan, R.G.
Deposit date:2009-07-14
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR.
J.Mol.Biol., 398, 2010
5DL2
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BU of 5dl2 by Molmil
Crystal Structure of RopB
Descriptor: Regulator of protease B (RopB)
Authors:Kumaraswami, M.
Deposit date:2015-09-04
Release date:2016-01-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes.
Mol.Microbiol., 99, 2016
4I7H
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BU of 4i7h by Molmil
Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes
Descriptor: NICKEL (II) ION, ZINC ION, peroxide stress sensing regulator
Authors:Kumaraswami, M.
Deposit date:2012-11-30
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Peroxide Stress Regulator from Streptococcus pyogenes Provides Functional Insights into the Mechanism of Oxidative Stress Sensing.
J.Biol.Chem., 288, 2013
3ECO
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BU of 3eco by Molmil
Crystal structure of MepR, a transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA
Descriptor: MepR, SULFATE ION
Authors:Brennan, R.G, Kumaraswami, M.
Deposit date:2008-09-01
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA.
Nucleic Acids Res., 37, 2009
6DQL
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BU of 6dql by Molmil
Crystal structure of Regulator of Proteinase B RopB complexed with SIP
Descriptor: Regulator of Proteinase B RopB, SpeB-inducing peptide (SIP)
Authors:Do, H, Makthal, N, VanderWal, A.R, Olsen, R.J, Musser, J.M, Kumaraswami, M.
Deposit date:2018-06-11
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway.
Nat Commun, 10, 2019
6O5C
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BU of 6o5c by Molmil
X-ray crystal structure of metal-dependent transcriptional regulator MtsR
Descriptor: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Putative metal-dependent transcriptional regulator
Authors:Do, H, Kumaraswami, M.
Deposit date:2019-03-01
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.
Nucleic Acids Res., 47, 2019
6OF0
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BU of 6of0 by Molmil
Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae
Descriptor: HTH-type transcriptional regulator MtrR, PHOSPHATE ION
Authors:Beggs, G.A, Kumaraswami, M, Shafer, W, Brennan, R.G.
Deposit date:2019-03-28
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae .
J.Bacteriol., 201, 2019
5JLS
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BU of 5jls by Molmil
Crystal Structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes (C-terminally His tagged)
Descriptor: Adhesin competence repressor, ZINC ION
Authors:Do, H, Kumaraswami, M.
Deposit date:2016-04-27
Release date:2017-05-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
To Be Published
5JLU
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BU of 5jlu by Molmil
Crystal Structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
Descriptor: Adhesin competence repressor, ZINC ION
Authors:Do, H, Kumaraswami, M.
Deposit date:2016-04-27
Release date:2017-05-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
To Be Published
3RJP
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BU of 3rjp by Molmil
Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
Descriptor: CovR
Authors:Horstmann, N.M, Brennan, R.G, Shelburne, S.A.
Deposit date:2011-04-15
Release date:2012-04-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
To be Published
3M9A
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BU of 3m9a by Molmil
Protein structure of type III plasmid segregation TubR
Descriptor: Putative DNA-binding protein
Authors:Schumacher, M.A, Ni, L.
Deposit date:2010-03-21
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M89
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BU of 3m89 by Molmil
Structure of TubZ-GTP-g-S
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, FtsZ/tubulin-related protein
Authors:Ni, L, Xu, W, Schumacher, M.A.
Deposit date:2010-03-17
Release date:2010-07-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M8F
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BU of 3m8f by Molmil
Protein structure of type III plasmid segregation TubR mutant
Descriptor: Putative DNA-binding protein
Authors:Schumacher, M.A, Ni, L.
Deposit date:2010-03-17
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M8K
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BU of 3m8k by Molmil
Protein structure of type III plasmid segregation TubZ
Descriptor: FtsZ/tubulin-related protein
Authors:Schumacher, M.A, Ni, L.
Deposit date:2010-03-18
Release date:2010-07-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M8E
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BU of 3m8e by Molmil
Protein structure of Type III plasmid segregation TubR
Descriptor: Putative DNA-binding protein
Authors:Ni, L, Schumacher, M.A.
Deposit date:2010-03-17
Release date:2010-07-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010

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