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7C0M
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BU of 7c0m by Molmil
Human cGAS-nucleosome complex
Descriptor: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1-B/E, ...
Authors:Kujirai, T, Zierhut, C, Takizawa, Y, Kim, R, Negishi, L, Uruma, N, Hirai, S, Funabiki, H, Kurumizaka, H.
Deposit date:2020-05-01
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for the inhibition of cGAS by nucleosomes.
Science, 370, 2020
5AY8
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BU of 5ay8 by Molmil
Crystal structure of human nucleosome containing H3.Y
Descriptor: CHLORIDE ION, DNA (146-MER), H3.Y, ...
Authors:Kujirai, T, Horikoshi, N, Sato, K, Maehara, K, Machida, S, Osakabe, A, Kimura, H, Ohkawa, Y, Kurumizaka, H.
Deposit date:2015-08-10
Release date:2016-04-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and function of human histone H3.Y nucleosome
Nucleic Acids Res., 44, 2016
6A5L
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BU of 6a5l by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA
Descriptor: DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-24
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5R
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BU of 6a5r by Molmil
RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5T
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BU of 6a5t by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5U
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BU of 6a5u by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation
Descriptor: DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5P
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BU of 6a5p by Molmil
RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5O
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BU of 6a5o by Molmil
RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6INQ
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BU of 6inq by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position)
Descriptor: DNA (198-MER), DNA (31-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-10-26
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
5B3N
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BU of 5b3n by Molmil
The crystal structure of anti-H4K20me1_scFv, 15F11
Descriptor: anti-H4K20me1_scFv
Authors:Kujirai, T, Horikoshi, N, Kurumizaka, H.
Deposit date:2016-03-04
Release date:2016-09-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation
J.Mol.Biol., 428, 2016
7DBH
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BU of 7dbh by Molmil
The mouse nucleosome structure containing H3mm18
Descriptor: DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
Authors:Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H.
Deposit date:2020-10-20
Release date:2022-01-19
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant.
Nucleic Acids Res., 50, 2022
6KXV
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BU of 6kxv by Molmil
Crystal structure of a nucleosome containing Leishmania histone H3
Descriptor: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Dacher, M, Taguchi, H, Kujirai, T, Kurumizaka, H.
Deposit date:2019-09-13
Release date:2020-07-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.63 Å)
Cite:Incorporation and influence of Leishmania histone H3 in chromatin.
Nucleic Acids Res., 47, 2019
6KVD
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BU of 6kvd by Molmil
Crystal structure of human nucleosome containing H2A.J
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A.J, ...
Authors:Tanaka, H, Koyama, M, Sato, S, Kujirai, T, Kurumizaka, H.
Deposit date:2019-09-04
Release date:2019-12-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Biochemical and structural analyses of the nucleosome containing human histone H2A.J.
J.Biochem., 167, 2020
8JLB
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BU of 8jlb by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
8JLD
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BU of 8jld by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
8JL9
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BU of 8jl9 by Molmil
Cryo-EM structure of the human nucleosome with scFv
Descriptor: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
8JLA
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BU of 8jla by Molmil
Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4
Descriptor: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
8JH3
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BU of 8jh3 by Molmil
RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH4
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BU of 8jh4 by Molmil
RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH2
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BU of 8jh2 by Molmil
RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
7VBM
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BU of 7vbm by Molmil
The mouse nucleosome structure containing H3mm18 aided by PL2-6 scFv
Descriptor: DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
Authors:Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H.
Deposit date:2021-08-31
Release date:2022-01-19
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant.
Nucleic Acids Res., 50, 2022
8HE5
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BU of 8he5 by Molmil
RNA polymerase II elongation complex bound with Rad26 and Elf1, stalled at SHL(-3.5) of the nucleosome
Descriptor: DNA (198-MER), DNA repair protein, DNA-directed RNA polymerase subunit, ...
Authors:Osumi, K, Kujirai, T, Ehara, H, Kinoshita, C, Saotome, M, Kagawa, W, Sekine, S, Takizawa, Y, Kurumizaka, H.
Deposit date:2022-11-07
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (6.95 Å)
Cite:Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
8KB5
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BU of 8kb5 by Molmil
Cryo-EM structure of the human nucleosome containing H3.8
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Hirai, H, Kujirai, T, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-08-03
Release date:2023-10-18
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.26133 Å)
Cite:Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8.
J.Biochem., 174, 2023
6IR9
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BU of 6ir9 by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2018-11-12
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6J50
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BU of 6j50 by Molmil
RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome (tilted conformation)
Descriptor: DNA (198-MER), DNA (41-MER), DNA-directed RNA polymerase subunit, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019

 

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