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3X2R
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BU of 3x2r by Molmil
Structure of the nonameric bacterial amyloid secretion channel CsgG
Descriptor: CsgG
Authors:Huang, Y, Cao, B, Zhao, Y, Kou, Y, Ni, D, Zhang, X.C.
Deposit date:2014-12-29
Release date:2015-01-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the nonameric bacterial amyloid secretion channel
Proc.Natl.Acad.Sci.USA, 111, 2014
6WIV
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BU of 6wiv by Molmil
Structure of human GABA(B) receptor in an inactive state
Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-{[(9Z)-octadec-9-enoyl]oxy}propyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Park, J, Fu, Z, Frangaj, A, Liu, J, Mosyak, L, Shen, T, Slavkovich, V.N, Ray, K.M, Taura, J, Cao, B, Geng, Y, Zuo, H, Kou, Y, Grassucci, R, Chen, S, Liu, Z, Lin, X, Williams, J.P, Rice, W.J, Eng, E.T, Huang, R.K, Soni, R.K, Kloss, B, Yu, Z, Javitch, J.A, Hendrickson, W.A, Slesinger, P.A, Quick, M, Graziano, J, Yu, H, Fiehn, O, Clarke, O.B, Frank, J, Fan, Q.R.
Deposit date:2020-04-10
Release date:2020-07-01
Last modified:2020-08-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of human GABABreceptor in an inactive state.
Nature, 584, 2020
4Q79
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BU of 4q79 by Molmil
Structure of a HG-derivative CsgG
Descriptor: CsgG, MERCURY (II) ION
Authors:Huang, Y, Zhang, C.X, Cao, B, Zhao, Y, Kou, Y, Ni, D.
Deposit date:2014-04-24
Release date:2014-12-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the nonameric bacterial amyloid secretion channel
Proc.Natl.Acad.Sci.USA, 111, 2014
6CRH
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BU of 6crh by Molmil
Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2018-03-17
Release date:2019-03-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.327 Å)
Cite:Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
Molecules, 24, 2019
4YMO
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BU of 4ymo by Molmil
Structure of human DNA polymerase beta complexed with N7BG in the template opposite to incoming non-hydrolyzable CTP WITH MANGANESE IN THE ACTIVE SITE
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA 10-mer (up-primer), DNA 16-mer (template), ...
Authors:Lee, S, Koag, M.-C.
Deposit date:2015-03-07
Release date:2016-03-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication.
Biochemistry, 2018
4YMN
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BU of 4ymn by Molmil
Structure of human DNA polymerase beta complexed with N7BG in the template base paired with incoming non-hydrolyzable CTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA 10-mer (up-primer), DNA 16-mer (template), ...
Authors:Lee, S, Koag, M.-C.
Deposit date:2015-03-06
Release date:2016-03-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.591 Å)
Cite:Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication.
Biochemistry, 2018
4YN4
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BU of 4yn4 by Molmil
Structure of human DNA polymerase beta complexed with N7BG in the template opposite to incoming non-hydrolyzable dTTP WITH MANGANESE IN THE ACTIVE SITE
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA 10-mer (up-primer), DNA 16-mer (template), ...
Authors:Lee, S, Koag, M.-C.
Deposit date:2015-03-09
Release date:2016-03-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication.
Biochemistry, 2018
5DB6
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BU of 5db6 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dC
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-20
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DBC
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BU of 5dbc by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DB7
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BU of 5db7 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dT
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DBA
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BU of 5dba by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dT
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.965 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DB8
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BU of 5db8 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DBB
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BU of 5dbb by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DB9
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BU of 5db9 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5EOZ
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BU of 5eoz by Molmil
Mutagenicity of 7-Benzyl guanine lesion and Replication by Human DNA Polymerase beta
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(GFL)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-11-10
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.088 Å)
Cite:Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication.
Biochemistry, 2018
7E6T
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BU of 7e6t by Molmil
Structural insights into the activation of human calcium-sensing receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYCLOMETHYLTRYPTOPHAN, ...
Authors:Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y.
Deposit date:2021-02-24
Release date:2021-09-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the activation of human calcium-sensing receptor.
Elife, 10, 2021
7E6U
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BU of 7e6u by Molmil
the complex of inactive CaSR and NB2D11
Descriptor: Extracellular calcium-sensing receptor, NB-2D11
Authors:Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y.
Deposit date:2021-02-24
Release date:2021-09-22
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural insights into the activation of human calcium-sensing receptor.
Elife, 10, 2021
4JCH
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BU of 4jch by Molmil
OSH4 bound to an electrophilic oxysterol
Descriptor: (3beta,9beta,22R,25R)-3-hydroxyfurost-5-en-27-yl propanoate, Protein KES1
Authors:Koag, M.C, Kou, Y.I, Monzingo, A.F, Lee, S.
Deposit date:2013-02-21
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of OSH4 bound to an electrophilic oxysterol
To be Published
4F4B
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BU of 4f4b by Molmil
Structure of OSH4 with a cholesterol analog
Descriptor: (3beta,9beta,25R)-3-hydroxy-26-iodocholest-5-ene-16,22-dione, Protein KES1
Authors:Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S.
Deposit date:2012-05-10
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
4FES
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BU of 4fes by Molmil
Structure of OSH4 in complex with cholesterol analogs
Descriptor: (3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2S,6S)-6-methyl-3-oxooctan-2-yl]-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-16H-cyclopenta[a]phenanthren-16-one, Protein KES1
Authors:Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S.
Deposit date:2012-05-30
Release date:2013-06-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
6BZ1
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BU of 6bz1 by Molmil
MEF2 Chimera D83V mutant/DNA complex
Descriptor: DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(P*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), MEF2 CHIMERA
Authors:Lei, X, Chen, L.
Deposit date:2017-12-21
Release date:2018-02-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:The Cancer Mutation D83V Induces an alpha-Helix to beta-Strand Conformation Switch in MEF2B.
J. Mol. Biol., 430, 2018
6BYY
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BU of 6byy by Molmil
MEF2 CHIMERA/DNA Complex
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 3,3',3''-phosphanetriyltripropanoic acid, DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), ...
Authors:Lei, X, Chen, L.
Deposit date:2017-12-21
Release date:2018-01-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Cancer Mutation D83V Induces an alpha-Helix to beta-Strand Conformation Switch in MEF2B.
J. Mol. Biol., 430, 2018
6UI2
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BU of 6ui2 by Molmil
Structure of human DNA polymerase eta complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(FMG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2019-09-30
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase eta.
Molecules, 24, 2019
4O5C
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BU of 4o5c by Molmil
Structure of human DNA polymerase complexed with N7-MG as the template base in a 1-nucleotide gapped DNA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2013-12-19
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.363 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
4O5E
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BU of 4o5e by Molmil
Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2013-12-19
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.532 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014

 

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