Author results

2QJ9
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CRYSTAL STRUCTURE ANALYSIS OF BMP-2 IN COMPLEX WITH BMPR-IA VARIANT B1
Descriptor:Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Kotzsch, A., Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJA
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CRYSTAL STRUCTURE ANALYSIS OF BMP-2 IN COMPLEX WITH BMPR-IA VARIANT B12
Descriptor:Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Kotzsch, A., Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJB
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CRYSTAL STRUCTURE ANALYSIS OF BMP-2 IN COMPLEX WITH BMPR-IA VARIANT IA/IB
Descriptor:Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION
Authors:Kotzsch, A., Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
3EVS
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CRYSTAL STRUCTURE OF THE GDF-5:BMP RECEPTOR IB COMPLEX.
Descriptor:Growth/differentiation factor 5, Bone morphogenetic protein receptor type-1B
Authors:Kotzsch, A., Mueller, T.D.
Deposit date:2008-10-13
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
Embo J., 28, 2009
3IQ2
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HUMAN SORTING NEXIN 7, PHOX HOMOLOGY (PX) DOMAIN
Descriptor:Sorting nexin-7, GLYCEROL, SULFATE ION
Authors:Karlberg, T., Wisniewska, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Kotzsch, A., Kraulis, P., Nielsen, T.K., Moche, M., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-08-19
Release date:2009-09-08
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human Sorting Nexin 7, Phox Homology (Px) Domain
To be Published
3K2I
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HUMAN ACYL-COENZYME A THIOESTERASE 4
Descriptor:Acyl-coenzyme A thioesterase 4, NICKEL (II) ION, CHLORIDE ION
Authors:Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-09-30
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human Acyl-coenzyme A thioesterase 4
To be Published
3KVH
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CRYSTAL STRUCTURE OF HUMAN PROTEIN SYNDESMOS (NUDT16-LIKE PROTEIN)
Descriptor:Protein syndesmos, GLYCEROL, CHLORIDE ION
Authors:Tresaugues, L., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Kotzsch, A., Kraulis, P., Moche, M., Nielsen, T.K., Nyman, T., Persson, C., Roos, A.K., Schuler, H., Schutz, P., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2009-11-30
Release date:2010-01-19
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human protein syndesmos (NUDT16L1)
To be Published
3HKV
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 10, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR 3-AMINOBENZAMIDE
Descriptor:Poly [ADP-ribose] polymerase 10, PHOSPHATE ION, SODIUM ION, ...
Authors:Karlberg, T., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Kotzsch, A., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Sagemark, J., Schutz, P., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-05-26
Release date:2009-06-16
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human Poly(Adp-Ribose) Polymerase 10, Catalytic Fragment in Complex with an Inhibitor 3-Aminobenzamide
To be Published
3I35
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HUMAN SH3 DOMAIN OF PROTEIN LASP1
Descriptor:LIM and SH3 domain protein 1
Authors:Siponen, M.I., Roos, A.K., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Kragh Nielsen, T., Moche, M., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Schutz, P., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2009-06-30
Release date:2009-09-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Human SH3 domain of protein LASP1
TO BE PUBLISHED
3IHJ
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HUMAN ALANINE AMINOTRANSFERASE 2 IN COMPLEX WITH PLP
Descriptor:Alanine aminotransferase 2, PYRIDOXAL-5'-PHOSPHATE, PHOSPHATE ION
Authors:Wisniewska, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-07-30
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human glutamate pyruvate transaminase 2
To be Published
3IHL
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HUMAN CTPS2 CRYSTAL STRUCTURE
Descriptor:CTP synthase 2, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
Authors:Moche, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Kragh Nielsen, T., Nyman, T., Persson, C., Roos, A.K., Sagemark, J., Schueler, H., Schutz, P., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2009-07-30
Release date:2009-10-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human CTPS2 crystal structure
To be Published
3IHY
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HUMAN PIK3C3 CRYSTAL STRUCTURE
Descriptor:Phosphatidylinositol 3-kinase catalytic subunit type 3
Authors:Siponen, M.I., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Kragh Nielsen, T., Moche, M., Nyman, T., Persson, C., Roos, A.K., Sagemark, J., Schueler, H., Schutz, P., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2009-07-31
Release date:2009-10-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human PIK3C3 crystal structure
TO BE PUBLISHED
2K3G
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NMR STRUCTURE ANALYSIS OF A BMP RECEPTOR
Descriptor:Bone morphogenetic protein receptor type-1A
Authors:Klages, J., Kotzsch, A., Mueller, T., Kessler, H.
Deposit date:2008-05-07
Release date:2008-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding.
Biochemistry, 47, 2008
3QT2
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STRUCTURE OF A CYTOKINE LIGAND-RECEPTOR COMPLEX
Descriptor:Interleukin-5 receptor subunit alpha, Interleukin-5, BETA-D-GLUCOSE, ...
Authors:Mueller, T.D., Patino, E., Kotzsch, A., Saremba, S., Nickel, J., Schmitz, W., Sebald, W.
Deposit date:2011-02-22
Release date:2012-02-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure Analysis of the IL-5 Ligand-Receptor Complex Reveals a Wrench-like Architecture for IL-5Ralpha.
Structure, 19, 2011
2WGH
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HUMAN RIBONUCLEOTIDE REDUCTASE R1 SUBUNIT (RRM1) IN COMPLEX WITH DATP AND MG.
Descriptor:RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT, GLYCEROL, MAGNESIUM ION, ...
Authors:Welin, R.M., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kragh-Nielsen, T., Kotzsch, A., Kotenyova, T., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Schutz, P., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wisniewska, M., Nordlund, P.
Deposit date:2009-04-19
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Allosteric Regulation of Human Ribonucleotide Reductase by Nucleotide-Induced Oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
3IUY
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CRYSTAL STRUCTURE OF DDX53 DEAD-BOX DOMAIN
Descriptor:Probable ATP-dependent RNA helicase DDX53, ADENOSINE MONOPHOSPHATE, CHLORIDE ION
Authors:Schutz, P., Karlberg, T., Collins, R., Arrowsmith, C.H., Berglund, H., Bountra, C., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H.M., Structural Genomics Consortium (SGC)
Deposit date:2009-08-31
Release date:2009-10-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
3JXU
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CRYSTAL STRUCTURE OF THE HUMAN 70KDA HEAT SHOCK PROTEIN 1A (HSP70-1) ATPASE DOMAIN IN COMPLEX WITH ADP AND INORGANIC PHOSPHATE
Descriptor:Heat shock 70 kDa protein 1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wisniewska, M.M., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-09-21
Release date:2009-10-20
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One, 5, 2010
3KCZ
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 2, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR 3-AMINOBENZAMIDE
Descriptor:Poly [ADP-ribose] polymerase 2, 3-aminobenzamide, GLYCEROL
Authors:Karlberg, T., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Kotzsch, A., Kraulis, P., Nielsen, T.K., Moche, M., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-10-22
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.
Biochemistry, 49, 2010
3KJD
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 2, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR ABT-888
Descriptor:Poly [ADP-ribose] polymerase 2, (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, GLYCEROL
Authors:Karlberg, T., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Kotzsch, A., Kraulis, P., Nielsen, T.K., Moche, M., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-11-03
Release date:2009-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.
Biochemistry, 49, 2010
3KR7
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HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN
Descriptor:Tankyrase-2, ZINC ION, SULFATE ION, ...
Authors:Karlberg, T., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Kotzsch, A., Kraulis, P., Nielsen, T.K., Moche, M., Nordlund, P., Nyman, T., Persson, C., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-11-18
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.
J.Med.Chem., 53, 2010
3KR8
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HUMAN TANKYRASE 2 - CATALYTIC PARP DOMAIN IN COMPLEX WITH AN INHIBITOR XAV939
Descriptor:Tankyrase-2, ZINC ION, 2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol, ...
Authors:Karlberg, T., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Kotzsch, A., Kraulis, P., Nielsen, T.K., Moche, M., Nordlund, P., Nyman, T., Persson, C., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-11-18
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.
J.Med.Chem., 53, 2010
3LLM
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CRYSTAL STRUCTURE ANALYSIS OF A RNA HELICASE
Descriptor:ATP-dependent RNA helicase A, MANGANESE (II) ION, CACODYLATE ION, ...
Authors:Schutz, P., Karlberg, T., Collins, R., Arrowsmith, C.H., Berglund, H., Bountra, C., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H.M., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.
J.Mol.Biol., 400, 2010
3LY5
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DDX18 DEAD-DOMAIN
Descriptor:ATP-dependent RNA helicase DDX18, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Schutz, P., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Kotzsch, A., Markova, N., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H.M., Structural Genomics Consortium (SGC)
Deposit date:2010-02-26
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
3H9U
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S-ADENOSYL HOMOCYSTEINE HYDROLASE (SAHH) FROM TRYPANOSOMA BRUCEI
Descriptor:Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENOSINE, ...
Authors:Siponen, M.I., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kragh Nielsen, T., Kotenyova, T., Kotzsch, A., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schueler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-04-30
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei
To be Published
3I33
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CRYSTAL STRUCTURE OF THE HUMAN 70KDA HEAT SHOCK PROTEIN 2 (HSP70-2) ATPASE DOMAIN IN COMPLEX WITH ADP AND INORGANIC PHOSPHATE
Descriptor:Heat shock-related 70 kDa protein 2, PHOSPHATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Wisniewska, M., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Kotzsch, A., Nielsen, T.K., Nordlund, P., Nyman, T., Moche, M., Persson, C., Roos, A.K., Sagemark, J., Schutz, P., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van den Berg, S., Weigelt, J., Welin, M., Schueler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-06-30
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One, 5, 2010
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