Author results

2MBL
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED TOP7 FOLD PROTEIN TOP7M13, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR33
Descriptor:Top7 Fold Protein Top7m13
Authors:Liu, G., Zanghellini, A.L., Chan, K., Xiao, R., Janjua, H., Kogan, S., Maglaqui, M., Ciccosanti, C., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-08-02
Release date:2013-11-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33
To be Published
2MBM
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED TOP7 FOLD PROTEIN TOP7M13, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR33
Descriptor:Top7 Fold Protein Top7m13
Authors:Liu, G., Zanghellini, A.L., Chan, K., Xiao, R., Janjua, H., Kogan, S., Maglaqui, M., Ciccosanti, C., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-08-02
Release date:2013-11-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33
To be Published
2MR5
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR457
Descriptor:De novo designed Protein OR457
Authors:Pulavarti, S., Nivon, L., Maglaqui, M., Janjua, H., Mao, L., Xiao, R., Kornhaber, G., Baker, D., Montelione, G., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-07-01
Release date:2014-09-17
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed Protein, Northeast Structural Genomics Consortium (NESG) Target OR457
To be Published
2MTL
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED FR55, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR109
Descriptor:De novo designed protein FR55 OR109
Authors:Liu, G., Koga, N., Koga, R., Xiao, R., Hamilton, K., Ciccosanti, C., Sahdev, S., Kohan, E., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-08-19
Release date:2014-10-29
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed FR55, Northeast Structural Genomics Consortium (NESG) Target OR109
To be Published
2N2T
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN (FDA_60), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR303
Descriptor:OR303
Authors:Liu, G., Lin, Y., Koga, N., Koga, R., Xiao, R., Janjua, H., Hamilton, K., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-05-14
Release date:2015-09-16
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303
To be Published
2N2U
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED FERREDOXIN FOLD PROTEIN SFR3, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR358
Descriptor:OR358
Authors:Liu, G., Lin, Y., Koga, N., Koga, R., Xiao, R., Janjua, H., Hamilton, K., Pederson, K., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-05-14
Release date:2015-09-16
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED Ferredoxin Fold PROTEIN sfr3, Northeast Structural Genomics Consortium (NESG) Target OR358
To be Published
2N3Z
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, ROSSMANN2X2 FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR446
Descriptor:OR446
Authors:Liu, G., Lin, Y., Koga, N., Koga, R., Xiao, R., Janjua, H., Pederson, K., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-06-15
Release date:2015-09-16
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED PROTEIN, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446
To be Published
2N41
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN TOP7NNSTYCC, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR34
Descriptor:OR34
Authors:Liu, G., Chan, K., Basanta, B., Xiao, R., Janjua, H., Kogan, S., Maglaqui, M., Ciccosanti, C., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-06-16
Release date:2016-03-02
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34
To be Published
2N4E
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN TOP7NNSTYCC, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR34
Descriptor:OR34
Authors:Liu, G., Chan, K., Basanta, B., Xiao, R., Janjua, H., Kogan, S., Maglaqui, M., Ciccosanti, C., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-06-17
Release date:2015-12-09
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34
To be Published
2N75
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, ROSSMANN2X2 FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR446
Descriptor:De novo designed protein
Authors:Liu, G., Lin, Y., Koga, N., Koga, R., Xiao, R., Janjua, H., Pederson, K., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-09-03
Release date:2016-01-27
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446
To be Published
2N76
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN LFR1 1 WITH FERREDOXIN FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR414
Descriptor:De novo designed protein LFR1
Authors:Liu, G., Lin, Y., Koga, N., Koga, R., Xiao, R., Janjua, H., Pederson, K., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-09-03
Release date:2016-01-27
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414
To be Published
4JXI
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DIRECTED EVOLUTION AND RATIONAL DESIGN OF A DE NOVO DESIGNED ESTERASE TOWARD IMPROVED CATALYSIS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR184
Descriptor:design cystein esterase, BROMIDE ION, GLYCEROL, ...
Authors:Kuzin, A., Smith, M.D., Richter, F., Lew, S., Seetharaman, R., Bryan, C., Lech, Z., Kiss, G., Moretti, R., Maglaqui, M., Xiao, R., Kohan, E., Smith, M., Everett, J.K., Nguyen, R., Pande, V., Hilvert, D., Kornhaber, G., Baker, D., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-03-28
Release date:2013-05-22
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184
To be Published
2MR6
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR462
Descriptor:De novo designed Protein OR462
Authors:Xu, X., Nivon, L., Federizon, J.F., Maglaqui, M., Janjua, H., Mao, L., Xiao, R., Kornhaber, G., Baker, D., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-07-01
Release date:2014-08-06
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed protein, Northeast Structural Genomics Consortium (NESG) Target OR462
To be Published
2MRA
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR459
Descriptor:De novo designed protein OR459
Authors:Pulavarti, S.V.S.R.K., Kipnis, Y., Sukumaran, D., Maglaqui, M., Janjua, H., Mao, L., Xiao, R., Kornhaber, G., Baker, D., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-07-02
Release date:2014-09-17
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed protein, Northeast Structural Genomics Consortium (NESG) Target OR459
To be Published
4KAC
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X-RAY STRUCTURE OF THE COMPLEX HALOTAG2 WITH HALTS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR150.
Descriptor:Haloalkane dehalogenase, N-(2-ethoxy-3,5-dimethylbenzyl)-1H-tetrazol-5-amine, AMMONIUM ION, ...
Authors:Kuzin, A., Lew, S., Neklesa, T.K., Noblin, D., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Kornhaber, G., Montelione, G.T., Crews, C.M., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-04-22
Release date:2013-06-05
Method:X-RAY DIFFRACTION (2.223 Å)
Cite:Northeast Structural Genomics Consortium Target OR150
To be Published
4KAF
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CRYSTAL STRUCTURE OF HALOALKANE DEHALOGENASE HALOTAG7 AT THE RESOLUTION 1.5A, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR151
Descriptor:Haloalkane dehalogenase, THIOCYANATE ION, SODIUM ION, ...
Authors:Kuzin, A.P., Lew, S., Neklesa, T.K., Noblin, D., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Kornhaber, G., Montelione, G.T., Crews, C., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-04-22
Release date:2013-06-05
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:Northeast Structural Genomics Consortium Target OR151
To be Published
4KAJ
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X-RAY STRUCTURE OF THE COMPLEX OF HALOALKANE DEHALOGENASE HALOTAG7 WITH HALTS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR151
Descriptor:PENTAETHYLENE GLYCOL, N-(2-ethoxy-3,5-dimethylbenzyl)-1H-tetrazol-5-amine, MANGANESE (II) ION, ...
Authors:Kuzin, A., Lew, S., Neklesa, T.K., Noblin, D., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Kornhaber, G., Montelione, G.T., Crews, C.M., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-04-22
Release date:2013-06-05
Method:X-RAY DIFFRACTION (1.948 Å)
Cite:Northeast Structural Genomics Consortium Target OR151
To be Published
4KYV
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CRYSTAL STRUCTURE OF DEHALOGENASE HALOTAG2 WITH HALTS AT THE RESOLUTION 1.8A. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR150
Descriptor:dehalogenase HaloTag2, N-(2-ethoxy-3,5-dimethylbenzyl)-1H-tetrazol-5-amine, SODIUM ION
Authors:Kuzin, A., Lew, S., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Kornhaber, G., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-05-29
Release date:2013-07-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Northeast Structural Genomics Consortium Target OR150
To be Published
4MPS
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CRYSTAL STRUCTURE OF RAT BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1 (ST6GAL1), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET RNR367A
Descriptor:Beta-galactoside alpha-2,6-sialyltransferase 1, N-ACETYL-D-GLUCOSAMINE
Authors:Forouhar, F., Meng, L., Milaninia, S., Seetharaman, J., Su, M., Kornhaber, G., Montelione, G.T., Hunt, J.F., Moremen, K.W., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-09-13
Release date:2013-09-25
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT alpha 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION.
J.Biol.Chem., 288, 2013
4NE7
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CRYSTAL STRUCTURE OF ENGINEERED KUMAMOLISIN-AS FROM ALICYCLOBACILLUS SENDAIENSIS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR367
Descriptor:Kumamolisin-As, ZINC ION
Authors:Guan, R., Pultz, I.S., Siegel, J.B., Seetharaman, J., Kornhaber, G., Maglaqui, M., Mao, L., Xiao, R., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-10-28
Release date:2013-11-20
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Northeast Structural Genomics Consortium Target OR367
To be Published
4ESS
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CRYSTAL STRUCTURE OF E6D/L155R VARIANT OF DE NOVO DESIGNED SERINE HYDROLASE OSH55, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR187
Descriptor:OR187
Authors:Kuzin, A., Su, M., Seetharaman, J., Kornhaber, K., Kornhaber, G., Rajagopalan, S., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-04-23
Release date:2012-06-13
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (1.9971 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
4ETJ
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CRYSTAL STRUCTURE OF E6H VARIANT OF DE NOVO DESIGNED SERINE HYDROLASE OSH55, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR185
Descriptor:Serine hydrolase, CHLORIDE ION, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
Authors:Kuzin, A., Su, M., Seetharaman, J., Kornhaber, K., Kornhaber, G., Rajagopalan, S., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
4ETK
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CRYSTAL STRUCTURE OF E6A/L130D/A155H VARIANT OF DE NOVO DESIGNED SERINE HYDROLASE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR186
Descriptor:De novo designed serine hydrolase, SODIUM ION
Authors:Kuzin, A., Su, M., Seetharaman, J., Kornhaber, K., Kornhaber, G., Rajagopalan, S., Baker, D., Everett, J.K., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
2LTA
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SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, ROSSMANN 3X1 FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR157
Descriptor:De novo designed protein
Authors:Liu, G., Koga, R., Koga, N., Xiao, R., Pederson, K., Hamilton, K., Kohan, E., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-05-15
Release date:2012-06-13
Last modified:2013-01-23
Method:SOLUTION NMR
Cite:Principles for designing ideal protein structures.
Nature, 491, 2012
2LVB
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SOLUTION NMR STRUCTURE DE NOVO DESIGNED PFK FOLD PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR250
Descriptor:DE NOVO DESIGNED PFK fold PROTEIN
Authors:Liu, G., Koga, N., Koga, R., Xiao, R., Hamilton, K., Kohan, E., Acton, T.B., Kornhaber, G., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-06-30
Release date:2012-08-08
Last modified:2013-01-23
Method:SOLUTION NMR
Cite:Principles for designing ideal protein structures.
Nature, 491, 2012
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