Author results

1Z14
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STRUCTURAL DETERMINANTS OF TISSUE TROPISM AND IN VIVO PATHOGENICITY FOR THE PARVOVIRUS MINUTE VIRUS OF MICE
分子名称:VP2
著者Kontou, M., Govindasamy, L., Nam, H.J., Bryant, N., Llamas-Saiz, A.L., Foces-Foces, C., Hernando, E., Rubio, M.P., McKenna, R., Almendral, J.M., Agbandje-McKenna, M.
登録日2005-03-03
公開日2005-09-06
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice.
J.Virol., 79, 2005
1Z1C
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STRUCTURAL DETERMINANTS OF TISSUE TROPISM AND IN VIVO PATHOGENICITY FOR THE PARVOVIRUS MINUTE VIRUS OF MICE
分子名称:5'-D(*AP*TP*CP*CP*TP*CP*TP*AP*TP*CP*AP*C)-3', 5'-D(*AP*CP*AP*CP*CP*AP*AP*AP*A)-3', Coat protein VP2, ...
著者Kontou, M., Govindasamy, L., Nam, H.J., Bryant, N., Llamas-Saiz, A.L., Foces-Foces, C., Hernando, E., Rubio, M.P., McKenna, R., Almendral, J.M., Agbandje-McKenna, M.
登録日2005-03-03
公開日2005-09-06
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice.
J.Virol., 79, 2005
1C5D
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THE CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF A RAT MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR
分子名称:MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR
著者Kontou, M., Leonidas, D.D., Vatzaki, E.H., Tsantili, P., Mamalaki, A., Oikonomakos, N.G., Acharya, K.R., Tzartos, S.J.
登録日1999-11-17
公開日1999-12-03
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor.
Eur.J.Biochem., 267, 2000
1GG8
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DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS
分子名称:PROTEIN (GLYCOGEN PHOSPHORYLASE), ALPHA-D-GLUCOPYRANOSYL-2-CARBOXYLIC ACID AMIDE, PYRIDOXAL-5'-PHOSPHATE, ...
著者Watson, K.A., Mitchell, E.P., Johnson, L.N., Son, J.C., Bichard, C.J., Orchard, M.G., Fleet, G.W., Oikonomakos, N.G., Leonidas, D.D., Kontou, M., Papageorgiou, A.C.
登録日2000-07-30
公開日2000-08-23
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.
Biochemistry, 33, 1994
2PRJ
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BINDING OF N-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE TO GLYCOGEN PHOSPHORYLASE B
分子名称:GLYCOGEN PHOSPHORYLASE, 1-N-ACETYL-BETA-D-GLUCOSAMINE, PYRIDOXAL-5'-PHOSPHATE, ...
著者Oikonomakos, N.G., Kontou, M., Zographos, S.E., Watson, K.A., Johnson, L.N., Bichard, C.J.F., Fleet, G.W.J., Acharya, K.R.
登録日1998-12-11
公開日1998-12-16
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献N-acetyl-beta-D-glucopyranosylamine: a potent T-state inhibitor of glycogen phosphorylase. A comparison with alpha-D-glucose.
Protein Sci., 4, 1995
1FN4
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CRYSTAL STRUCTURE OF FAB198, AN EFFICIENT PROTECTOR OF ACETYLCHOLINE RECEPTOR AGAINST MYASTHENOGENIC ANTIBODIES
分子名称:MONOCLONAL ANTIBODY AGAINST ACETYLCHOLINE RECEPTOR
著者Poulas, K., Eliopoulos, E., Vatzaki, E., Navaza, J., Kontou, M.
登録日2000-08-21
公開日2001-09-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies.
Eur.J.Biochem., 268, 2001
3DXG
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RIBONUCLEASE A- URIDINE 5' PHOSPHATE COMPLEX
分子名称:Ribonuclease pancreatic, URIDINE-5'-MONOPHOSPHATE
著者Tsirkone, V.G., Dossi, K., Leonidas, D.D., Zographos, S.E., Oikonomakos, N.G., Kontou, M.
登録日2008-07-24
公開日2009-06-16
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Inhibitor design to Ribonuclease A: The binding of two 5'phosphate uridine analogues
Acta Crystallogr.,Sect.F, 2009
3DXH
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RIBONUCLEASE A URIDINE 5' DIPHOSPHATE COMPLEX
分子名称:Ribonuclease pancreatic, URIDINE-5'-DIPHOSPHATE
著者Tsirkone, V.G., Dossi, K., Leonidas, D.D., Zographos, S.E., Oikonomakos, N.G., Kontou, M.
登録日2008-07-24
公開日2009-06-16
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inhibitor design to Ribonuclease A: The binding of two 5'phosphate uridine analogues
Acta Crystallogr.,Sect.F, 2009
3SYM
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH 3 -C-(HYDROXYMETHYL)-BETA-D-GLUCOPYRANONUCLEOSIDE OF 5-FLUOROURACIL
分子名称:Glycogen phosphorylase, muscle form, 5-fluoro-1-[3-C-(hydroxymethyl)-beta-D-glucopyranosyl]pyrimidine-2,4(1H,3H)-dione
著者Skamnaki, V.T., Katsandi, A.L., Kontou, M., Leonidas, D.D.
登録日2011-07-18
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献3'-Axial CH(2) OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM-PBSA Calculations Suggest Why.
Chem.Biol.Drug Des., 79, 2012
3SYR
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH BETA-D-GLUCOPYRANONUCLEOSIDE 5-FLUOROURACIL
分子名称:Glycogen phosphorylase, muscle form, 5-fluoro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione
著者Skamnaki, V.T., Kantsadi, A.L., Kontou, M., Leonidas, D.D.
登録日2011-07-18
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献3'-Axial CH(2) OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM-PBSA Calculations Suggest Why.
Chem.Biol.Drug Des., 79, 2012
1FS4
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:GLYCOGEN PHOSPHORYLASE, 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-09-08
公開日2000-10-04
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FTQ
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:GLYCOGEN PHOSPHORYLASE, 3-AMINO-8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, PYRIDOXAL-5'-PHOSPHATE, ...
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-09-13
公開日2000-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FTW
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:GLYCOGEN PHOSPHORYLASE, 3,8,9,10-TETRAHYDROXY-7-HYDROXYMETHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-09-13
公開日2000-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FTY
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:GLYCOGEN PHOSPHORYLASE, 8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-3-METHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-09-13
公開日2000-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FU4
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:GLYCOGEN PHOSPHORYLASE, N-(8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-2,4-DIOXO-6-OXA-1,3-DIAZA-SPIRO[4.5]DEC-3-YL-ACETAMIDE, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-09-14
公開日2000-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FU7
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:GLYCOGEN PHOSPHORYLASE, 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCOPYRANOSE, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-09-14
公開日2000-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FU8
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:GLYCOGEN PHOSPHORYLASE, 1-DEOXY-1-ACETYLAMINO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-09-14
公開日2000-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1GGN
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STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
分子名称:PROTEIN (GLYCOGEN PHOSPHORYLASE), BETA-D-GLUCOPYRANOSE SPIROHYDANTOIN, PYRIDOXAL-5'-PHOSPHATE
著者Watson, K.A., Tsitsanou, K.E., Gregoriou, M., Zographos, S.E., Skamnaki, V.T., Oikonomakos, N.G., Fleet, G.W., Johnson, L.N.
登録日2000-08-29
公開日2000-09-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase B.
Bioorg.Med.Chem., 10, 2002
3T3D
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH GLCU
分子名称:Glycogen phosphorylase, muscle form, 1-beta-D-glucopyranosylpyrimidine-2,4(1H,3H)-dione
著者Kantsadi, A.L., Skamnaki, V.T., Leonidas, D.D.
登録日2011-07-25
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3E
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH GLCCLU
分子名称:Glycogen phosphorylase, muscle form, 5-chloro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione
著者Kantsadi, A.L., Skamnaki, V.T., Leonidas, D.D.
登録日2011-07-25
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3G
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH GLCBRU
分子名称:Glycogen phosphorylase, muscle form, 5-bromo-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione
著者Kantsadi, A.L., Skamnaki, V.T., Leonidas, D.D.
登録日2011-07-25
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3H
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH GLCIU
分子名称:Glycogen phosphorylase, muscle form, 1-(beta-D-glucopyranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione
著者Kantsadi, A.L., Skamnaki, V.T., Leonidas, D.D.
登録日2011-07-25
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3I
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GLYCOGEN PHOSPHORYLASE B IN COMPLEX WITH GLCCF3U
分子名称:Glycogen phosphorylase, muscle form, 1-(beta-D-glucopyranosyl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione
著者Kantsadi, A.L., Skamnaki, V.T., Leonidas, D.D.
登録日2011-07-25
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
1A8I
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SPIROHYDANTOIN INHIBITOR OF GLYCOGEN PHOSPHORYLASE
分子名称:GLYCOGEN PHOSPHORYLASE B, BETA-D-GLUCOPYRANOSE SPIROHYDANTOIN
著者Gregoriou, M., Noble, M.E.M., Watson, K.A., Garman, E.F., Krulle, T.M., De La Fuente, C., Fleet, G.W.J., Oikonomakos, N.G., Johnson, L.N.
登録日1998-03-25
公開日1998-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
Protein Sci., 7, 1998
1B4D
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AMIDOCARBAMATE INHIBITOR OF GLYCOGEN PHOSPHORYLASE
分子名称:PROTEIN (GLYCOGEN PHOSPHORYLASE B), 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, PYRIDOXAL-5'-PHOSPHATE, ...
著者Tsitsanou, K.E., Oikonomakos, N.G., Zographos, S.E., Skamnaki, V.T., Gregoriou, M., Watson, K.A., Johnson, L.N., Fleet, G.W.J.
登録日1998-12-18
公開日1998-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure.
Protein Sci., 8, 1999
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