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6AGP
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BU of 6agp by Molmil
Structure of Rac1 in the low-affinity state for Mg2+
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1
Authors:Toyama, Y, Kontani, K, Katada, T, Shimada, I.
Deposit date:2018-08-13
Release date:2019-03-20
Last modified:2019-11-20
Method:SOLUTION NMR
Cite:Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR.
Sci Adv, 5, 2019
5XGC
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BU of 5xgc by Molmil
Crystal structure of SmgGDS-558
Descriptor: Rap1 GTPase-GDP dissociation stimulator 1
Authors:Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2017-04-13
Release date:2017-06-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding
J. Biol. Chem., 292, 2017
5ZHX
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BU of 5zhx by Molmil
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Descriptor: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA
Authors:Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2018-03-13
Release date:2018-09-05
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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