Author results

2F33
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NMR SOLUTION STRUCTURE OF CA2+-LOADED CALBINDIN D28K
分子名称:Calbindin
著者Kojetin, D.J., Venters, R.A., Kordys, D.R., Thompson, R.J., Kumar, R., Cavanagh, J.
登録日2005-11-18
公開日2006-07-04
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure, binding interface and hydrophobic transitions of Ca(2+)-loaded calbindin-D(28K).
Nat.Struct.Mol.Biol., 13, 2006
2G9B
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NMR SOLUTION STRUCTURE OF CA2+-LOADED CALBINDIN D28K
分子名称:Calbindin
著者Kojetin, D.J., Venters, R.A., Kordys, D.R., Thompson, R.J., Kumar, R., Cavanagh, J.
登録日2006-03-06
公開日2006-07-04
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure, binding interface and hydrophobic transitions of Ca(2+)-loaded calbindin-D(28K).
Nat.Struct.Mol.Biol., 13, 2006
2K77
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NMR SOLUTION STRUCTURE OF THE BACILLUS SUBTILIS CLPC N-DOMAIN
分子名称:Negative regulator of genetic competence clpC/mecB
著者Kojetin, D.J., McLaughlin, P.D., Thompson, R.J., Rance, M., Cavanagh, J.
登録日2008-08-04
公開日2009-04-28
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural and motional contributions of the Bacillus subtilis ClpC N-domain to adaptor protein interactions.
J.Mol.Biol., 387, 2009
4ZO1
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CRYSTAL STRUCTURE OF THE T3-BOUND TR-BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH RXR-ALPHA
分子名称:Thyroid hormone receptor beta, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha, ...
著者Bruning, J.B., Kojetin, D.J., Matta-Camacho, E., Hughes, T.S., Srinivasan, S., Nwachukwu, J.C., Cavett, V., Nowak, J., Chalmers, M.J., Marciano, D.P., Kamenecka, T.M., Rance, M., Shulman, A.I., Mangelsdorf, D.J., Griffin, P.R., Nettles, K.W.
登録日2015-05-05
公開日2015-09-02
実験手法X-RAY DIFFRACTION (3.221 Å)
主引用文献Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.
Nat Commun, 6, 2015
2L7F
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SOLUTION STRUCTURE OF THE PITX2 HOMEODOMAIN
分子名称:Pituitary homeobox 2
著者Doerdelmann, T., Rance, M., Baird-Titus, J.M., Kojetin, D.J.
登録日2010-12-08
公開日2011-12-14
実験手法SOLUTION NMR
主引用文献Solution Structure of the Pitx2 Homeodomain
To be Published
2L7M
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SOLUTION STRUCTURE OF THE PITX2 HOMEODOMAIN R24H MUTANT
分子名称:Pituitary homeobox 2
著者Doerdelmann, T., Rance, M., Kojetin, D.J., Baird-Titus, J.M.
登録日2010-12-14
公開日2011-12-14
実験手法SOLUTION NMR
主引用文献Solution Structure of the Pitx2 Homeodomain R24H mutant
To be Published
2RO4
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RDC-REFINED SOLUTION STRUCTURE OF THE N-TERMINAL DNA RECOGNITION DOMAIN OF THE BACILLUS SUBTILIS TRANSITION-STATE REGULATOR ABRB
分子名称:Transition state regulatory protein abrB
著者Sullivan, D.M., Bobay, B.G., Kojetin, D.J., Thompson, R.J., Rance, M., Strauch, M.A., Cavanagh, J.
登録日2008-03-08
公開日2008-11-11
最終更新日2012-01-11
実験手法SOLUTION NMR
主引用文献Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
2RO5
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RDC-REFINED SOLUTION STRUCTURE OF THE N-TERMINAL DNA RECOGNITION DOMAIN OF THE BACILLUS SUBTILIS TRANSITION-STATE REGULATOR SPOVT
分子名称:Stage V sporulation protein T
著者Sullivan, D.M., Bobay, B.G., Kojetin, D.J., Thompson, R.J., Rance, M., Strauch, M.A., Cavanagh, J.
登録日2008-03-08
公開日2008-11-11
最終更新日2012-04-04
実験手法SOLUTION NMR
主引用文献Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
4IU7
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH CONSTRAINED WAY-DERIVATIVE, 2B
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[2-ethyl-7-(trifluoromethyl)-2H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-20
公開日2013-03-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IUI
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DYNAMIC WAY DERIVATIVE, 4A
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[1-butyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-21
公開日2013-03-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IV2
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DYNAMIC WAY-DERIVATIVE, 5A
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[1-(2-methylpropyl)-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-22
公開日2013-03-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IV4
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH CONSTRAINED WAY-DERIVATIVE, 5B
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[2-(2-methylpropyl)-7-(trifluoromethyl)-2H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-22
公開日2013-03-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IVW
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH CONSTRAINED WAY-DERIVATIVE, 6B
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[2-benzyl-7-(trifluoromethyl)-2H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-23
公開日2013-03-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IVY
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DYNAMIC WAY-DERIVATIVE, 7A
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[1-(but-3-en-1-yl)-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-23
公開日2013-03-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IW6
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH CONSTRAINED WAY-DERIVATIVE, 7B
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[2-(but-3-en-1-yl)-7-(trifluoromethyl)-2H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-23
公開日2013-03-27
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IW8
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DYNAMIC WAY-DERIVATIVE, 9A
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4-[1-(3-methylbut-2-en-1-yl)-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-23
公開日2013-03-27
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.0375 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IWC
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A DYNAMIC THIOPHENE-DERIVATIVE
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-thiene-2,5-diylbis(3-methylphenol)
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-23
公開日2013-03-27
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4IWF
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A DYNAMIC OXIME-DERIVATIVE
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 2-chloro-3'-fluoro-3-[(E)-(hydroxyimino)methyl]biphenyl-4,4'-diol
著者Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
登録日2013-01-23
公開日2013-03-27
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (1.932 Å)
主引用文献Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Nat.Chem.Biol., 9, 2013
4PP6
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH RESVERATROL
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, RESVERATROL
著者Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Parent, A.A., Hughes, T.S., Pollock, J.A., Gjyshi, O., Cavett, V., Nowak, J., Garcia-Ordonez, R.D., Houtman, R., Griffin, P.R., Kojetin, D.J., Katzenellenbogen, J.A., Conkright, M.D., Nettles, K.W.
登録日2014-02-26
公開日2014-05-07
最終更新日2014-06-11
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife, 3, 2014
4PPP
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH FLUORO-RESVERATROL
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, 5-[(E)-2-(3-fluoro-4-hydroxyphenyl)ethenyl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Parent, A.A., Hughes, T.S., Pollock, J.A., Gjyshi, O., Cavett, V., Nowak, J., Garcia-Ordonez, R.D., Houtman, R., Griffin, P.R., Kojetin, D.J., Katzenellenbogen, J.A., Conkright, M.D., Nettles, K.W.
登録日2014-02-27
公開日2014-05-07
最終更新日2014-06-11
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife, 3, 2014
4PPS
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH AN A-CD RING ESTROGEN DERIVATIVE
分子名称:Estrogen receptor, Nuclear receptor coactivator 2, (1S,3aR,5R,7aS)-5-(4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol
著者Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Parent, A.A., Hughes, T.S., Pollock, J.A., Gjyshi, O., Cavett, V., Nowak, J., Garcia-Ordonez, R.D., Houtman, R., Griffin, P.R., Kojetin, D.J., Katzenellenbogen, J.A., Conkright, M.D., Nettles, K.W.
登録日2014-02-27
公開日2014-05-07
最終更新日2014-06-11
実験手法X-RAY DIFFRACTION (1.929 Å)
主引用文献Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife, 3, 2014
5KR9
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH COUMESTROL
分子名称:Estrogen receptor, NCOA2, Coumestrol
著者Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
登録日2016-07-07
公開日2017-02-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Cell Chem Biol, 24, 2017
5KRA
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH DDT AND DDE
分子名称:Estrogen receptor, NCOA2, 1-[2,2-bis(chloranyl)-1-(4-chlorophenyl)ethenyl]-4-chloranyl-benzene, ...
著者Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
登録日2016-07-07
公開日2017-02-15
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Cell Chem Biol, 24, 2017
5KRC
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH ZEARALENONE
分子名称:Estrogen receptor, NCOA2, (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione
著者Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
登録日2016-07-07
公開日2017-02-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Cell Chem Biol, 24, 2017
5KRF
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH THE DYNAMIC WAY DERIVATIVE, 1A
分子名称:Estrogen receptor, KHKILHRLLQDSSS Peptide, 4-[1-methyl-7-(trifluoromethyl)indazol-3-yl]benzene-1,3-diol
著者Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
登録日2016-07-07
公開日2017-02-15
実験手法X-RAY DIFFRACTION (2.193 Å)
主引用文献Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Cell Chem Biol, 24, 2017