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7BMQ
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BU of 7bmq by Molmil
HEWL in cesium chloride (1.71 M CsCl in cryo protectant)
Descriptor: 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMR
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BU of 7bmr by Molmil
HEWL in cesium chloride (0.25 M CsCl in protein buffer and 1.71 M CsCl in cryo protectant)
Descriptor: 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMS
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BU of 7bms by Molmil
HEWL in cesium chloride (1.5 M CsCl in crystallization condition and cryo protectant)
Descriptor: 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMX
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BU of 7bmx by Molmil
p62PH in cesium chloride (0.25 M CsCl in protein buffer and 0.75 M CsCl in cryo protectant)
Descriptor: CESIUM ION, CHLORIDE ION, RNA polymerase II transcription factor B 73 kDa subunit-like protein
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMP
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BU of 7bmp by Molmil
HEWL in cesium chloride (0.25 M CsCl in protein buffer and cryo protectant).
Descriptor: 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMZ
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BU of 7bmz by Molmil
p62PH in potassium chloride
Descriptor: CHLORIDE ION, POTASSIUM ION, RNA polymerase II transcription factor B 73 kDa subunit-like protein
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMV
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BU of 7bmv by Molmil
p62PH in cesium chloride (0.25 M CsCl in protein buffer and cryo protectant)
Descriptor: CESIUM ION, CHLORIDE ION, RNA polymerase II transcription factor B 73 kDa subunit-like protein
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMU
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BU of 7bmu by Molmil
p62PH in cesium chloride (0.25 M CsCl in protein buffer)
Descriptor: CESIUM ION, CHLORIDE ION, POTASSIUM ION, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMT
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BU of 7bmt by Molmil
HEWL in sodium chloride
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMO
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BU of 7bmo by Molmil
HEWL in cesium chloride (0.25 M CsCl in protein buffer)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Hen egg white lysozyme, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMY
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BU of 7bmy by Molmil
p62PH in cesium chloride (0.7 M CsCl in crystallization condition and cryo protectant)
Descriptor: CESIUM ION, CHLORIDE ION, RNA polymerase II transcription factor B 73 kDa subunit-like protein
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
7BMW
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BU of 7bmw by Molmil
p62PH in cesium chloride (0.75 M CsCl in cryo protectant)
Descriptor: CESIUM ION, CHLORIDE ION, RNA polymerase II transcription factor B 73 kDa subunit-like protein
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2021-01-20
Release date:2021-10-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Sci Rep, 11, 2021
6TRS
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BU of 6trs by Molmil
Crystal structure of TFIIH subunit p52 in complex with p8
Descriptor: RNA polymerase II transcription factor B subunit 2, Uncharacterized protein
Authors:Koelmel, W, Kuper, J, Schoenwetter, E, Kisker, C.
Deposit date:2019-12-19
Release date:2020-10-21
Last modified:2020-12-23
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:How to limit the speed of a motor: the intricate regulation of the XPB ATPase and translocase in TFIIH.
Nucleic Acids Res., 48, 2020
6TRU
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BU of 6tru by Molmil
Crystal structure of the N-terminal half of the TFIIH subunit p52
Descriptor: RNA polymerase II transcription factor B subunit 2
Authors:Koelmel, W, Kuper, J, Schoenwetter, E, Kisker, C.
Deposit date:2019-12-19
Release date:2020-10-21
Last modified:2020-12-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:How to limit the speed of a motor: the intricate regulation of the XPB ATPase and translocase in TFIIH.
Nucleic Acids Res., 48, 2020
5NUS
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BU of 5nus by Molmil
Structure of a minimal complex between p44 and p34 from Chaetomium thermophilum
Descriptor: ZINC ION, p34, p44
Authors:Koelmel, W, Schoenwetter, E, Kuper, J, Schmitt, D.R, Kisker, C.
Deposit date:2017-05-02
Release date:2017-10-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.
Nucleic Acids Res., 45, 2017
6ENT
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BU of 6ent by Molmil
Structure of the rat RKIP variant delta143-146
Descriptor: CHLORIDE ION, Phosphatidylethanolamine-binding protein 1, ZINC ION
Authors:Koelmel, W, Hirschbeck, M, Schindelin, H, Lorenz, K, Kisker, C.
Deposit date:2017-10-06
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5I4Z
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BU of 5i4z by Molmil
Structure of apo OmoMYC
Descriptor: CHLORIDE ION, GLYCEROL, Myc proto-oncogene protein, ...
Authors:Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C.
Deposit date:2016-02-13
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
Oncogene, 36, 2017
5I50
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BU of 5i50 by Molmil
Structure of OmoMYC bound to double-stranded DNA
Descriptor: DNA (5'-D(P*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*CP*TP*AP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*CP*GP*GP*GP*TP*G)-3'), Myc proto-oncogene protein
Authors:Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C.
Deposit date:2016-02-13
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
Oncogene, 36, 2017
7AD8
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BU of 7ad8 by Molmil
Core TFIIH-XPA-DNA complex with modelled p62 subunit
Descriptor: DNA (49-MER), DNA repair protein complementing XP-A cells, General transcription and DNA repair factor IIH helicase subunit XPB, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2020-09-14
Release date:2021-07-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair.
Nucleic Acids Res., 48, 2020
4F9Z
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BU of 4f9z by Molmil
Crystal Structure of human ERp27
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ACETATE ION, ...
Authors:Kober, F.X, Koelmel, W, Kuper, J, Schindelin, H.
Deposit date:2012-05-21
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of the Protein-Disulfide Isomerase Family Member ERp27 Provides Insights into Its Substrate Binding Capabilities.
J.Biol.Chem., 288, 2013
5OBZ
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BU of 5obz by Molmil
low resolution structure of the p34ct/p44ct minimal complex
Descriptor: Putative transcription factor, ZINC ION
Authors:Schoenwetter, E, Koelmel, W, Schmitt, D.R, Kuper, J, Kisker, C.
Deposit date:2017-06-29
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.
Nucleic Acids Res., 45, 2017
6ENS
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BU of 6ens by Molmil
Structure of mouse wild-type RKIP
Descriptor: ACETATE ION, GLYCEROL, Phosphatidylethanolamine-binding protein 1
Authors:Hirschbeck, M, Koelmel, W, Schindelin, H, Lorenz, K, Kisker, C.
Deposit date:2017-10-06
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5O85
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BU of 5o85 by Molmil
p34-p44 complex
Descriptor: General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, ZINC ION
Authors:Radu, L, Poterszman, A.
Deposit date:2017-06-12
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.
Nucleic Acids Res., 45, 2017
7ZUP
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BU of 7zup by Molmil
Human PRMT5:MEP50 structure with Fragment (Example 18) and MTA Bound
Descriptor: 3-ethylimidazo[4,5-b]pyridin-2-amine, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, ...
Authors:Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J.
Deposit date:2022-05-12
Release date:2022-10-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022
7ZVU
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BU of 7zvu by Molmil
HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ...
Authors:Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J.
Deposit date:2022-05-17
Release date:2022-10-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022

 

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