1AXG | | CRYSTAL STRUCTURE OF THE VAL203->ALA MUTANT OF LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH COFACTOR NAD AND INHIBITOR TRIFLUOROETHANOL SOLVED TO 2.5 ANGSTROM RESOLUTION | | Descriptor: | ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Colby, T.D., Chin, J.K., Bahnson, B.J., Goldstein, B.M., Klinman, J.P. | | Deposit date: | 1997-10-15 | | Release date: | 1998-04-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A link between protein structure and enzyme catalyzed hydrogen tunneling.
Proc.Natl.Acad.Sci.USA, 94, 1997
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1A71 | | TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL | | Descriptor: | LIVER ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Colby, T.D., Bahnson, B.J., Chin, J.K., Klinman, J.P., Goldstein, B.M. | | Deposit date: | 1998-03-19 | | Release date: | 1998-06-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
Biochemistry, 37, 1998
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1A72 | | AN ACTIVE-SITE DOUBLE MUTANT (PHE93->TRP, VAL203->ALA) OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH THE ISOSTERIC NAD ANALOG CPAD | | Descriptor: | HORSE LIVER ALCOHOL DEHYDROGENASE, ZINC ION, 5-BETA-D-RIBOFURANOSYLPICOLINAMIDE ADENINE-DINUCLEOTIDE | | Authors: | Colby, T.D., Bahnson, B.J., Chin, J.K., Klinman, J.P., Goldstein, B.M. | | Deposit date: | 1998-03-19 | | Release date: | 1998-06-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
Biochemistry, 37, 1998
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1EKM | | CRYSTAL STRUCTURE AT 2.5 A RESOLUTION OF ZINC-SUBSTITUTED COPPER AMINE OXIDASE OF HANSENULA POLYMORPHA EXPRESSED IN ESCHERICHIA COLI | | Descriptor: | COPPER AMINE OXIDASE, ZINC ION | | Authors: | Chen, Z., Schwartz, B., Williams, N.K., Li, R., Klinman, J.P., Mathews, F.S. | | Deposit date: | 2000-03-09 | | Release date: | 2000-08-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure at 2.5 A resolution of zinc-substituted copper amine oxidase of Hansenula polymorpha expressed in Escherichia coli.
Biochemistry, 39, 2000
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3N9H | | CRYSTAL STRUCTURAL OF MUTANT Y305A IN THE COPPER AMINE OXIDASE FROM HANSENULA POLYMORPHA | | Descriptor: | Peroxisomal primary amine oxidase, COPPER (II) ION | | Authors: | Chen, Z., Datta, S., DuBois, J.L., Klinman, J.P., Mathews, F.S. | | Deposit date: | 2010-05-30 | | Release date: | 2010-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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3NBB | | CRYSTAL STRUCTURE OF MUTANT Y305F EXPRESSED IN E. COLI IN THE COPPER AMINE OXIDASE FROM HANSENULA POLYMORPHA | | Descriptor: | Peroxisomal primary amine oxidase, COPPER (II) ION | | Authors: | Chen, Z., Datta, S., DuBois, J.L., Klinman, J.P., Mathews, F.S. | | Deposit date: | 2010-06-03 | | Release date: | 2010-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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3NBJ | | CRYSTAL STRUCTURE OF Y305F MUTANT OF THE COPPER AMINE OXIDASE FROM HANSENULA POLYMORPHA EXPRESSED IN YEAST | | Descriptor: | Peroxisomal primary amine oxidase, COPPER (II) ION, PHOSPHATE ION | | Authors: | Chen, Z., Datta, S., DuBois, J.L., Klinman, J.P., Mathews, F.S. | | Deposit date: | 2010-06-03 | | Release date: | 2010-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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1OTV | | PQQC, PYRROLOQUINOLINQUINONE SYNTHASE C | | Descriptor: | Coenzyme PQQ synthesis protein C | | Authors: | Magnusson, O.T., Toyama, H., Saeki, M., Rojas, A., Reed, J.C., Adachi, O., Klinman, J.P., SChwarzenbacher, R. | | Deposit date: | 2003-03-23 | | Release date: | 2004-05-11 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Quinone Biogenesis: Structure and Mechanism of PqqC, the Final Catalyst in the Production of Pyrroloquinoline Quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1OTW | | CRYSTAL STRUCTURE OF PQQC IN COMPLEX WITH PQQ AND A PUTATIVE H2O2 | | Descriptor: | Coenzyme PQQ synthesis protein C, PYRROLOQUINOLINE QUINONE, HYDROGEN PEROXIDE | | Authors: | Magnusson, O.T., Toyama, H., Saeki, M., Rojas, A., Reed, J.C., Liddington, R.C., Klinman, J.P., Schwarzenbacher, R. | | Deposit date: | 2003-03-23 | | Release date: | 2004-05-11 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1ZDR | | DHFR FROM BACILLUS STEAROTHERMOPHILUS | | Descriptor: | dihydrofolate reductase, SULFATE ION, GLYCEROL | | Authors: | Kim, H.S., Damo, S.M., Lee, S.Y., Wemmer, D., Klinman, J.P. | | Deposit date: | 2005-04-14 | | Release date: | 2005-08-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and hydride transfer mechanism of a moderate thermophilic dihydrofolate reductase from Bacillus stearothermophilus and comparison to its mesophilic and hyperthermophilic homologues.
Biochemistry, 44, 2005
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4WFO | |
4WHA | | LIPOXYGENASE-1 (SOYBEAN) L546A/L754A MUTANT | | Descriptor: | Seed linoleate 13S-lipoxygenase-1, FE (III) ION, 1,2-ETHANEDIOL, ... | | Authors: | Scouras, A.D., Carr, C.A.M., Hu, S., Klinman, J.P. | | Deposit date: | 2014-09-21 | | Release date: | 2014-11-12 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Extremely elevated room-temperature kinetic isotope effects quantify the critical role of barrier width in enzymatic C-H activation.
J.Am.Chem.Soc., 136, 2014
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3BNB | | LIPOXYGENASE-1 (SOYBEAN) I553L MUTANT | | Descriptor: | Seed lipoxygenase-1, FE (III) ION | | Authors: | Tomchick, D.R. | | Deposit date: | 2007-12-14 | | Release date: | 2008-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BNC | | LIPOXYGENASE-1 (SOYBEAN) I553G MUTANT | | Descriptor: | Seed lipoxygenase-1, FE (III) ION, ACETIC ACID | | Authors: | Tomchick, D.R. | | Deposit date: | 2007-12-14 | | Release date: | 2008-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BND | | LIPOXYGENASE-1 (SOYBEAN), I553V MUTANT | | Descriptor: | Seed lipoxygenase-1, FE (III) ION | | Authors: | Tomchick, D.R. | | Deposit date: | 2007-12-14 | | Release date: | 2008-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BNE | | LIPOXYGENASE-1 (SOYBEAN) I553A MUTANT | | Descriptor: | Seed lipoxygenase-1, FE (III) ION | | Authors: | Tomchick, D.R. | | Deposit date: | 2007-12-14 | | Release date: | 2008-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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5SXY | |
6OWM | | HORSE LIVER F93W ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL | | Descriptor: | Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... | | Authors: | Plapp, B.V. | | Deposit date: | 2019-05-10 | | Release date: | 2019-05-22 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
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6OWP | | HORSE LIVER F93W ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND TRIFLUOROETHANOL | | Descriptor: | Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... | | Authors: | Plapp, B.V. | | Deposit date: | 2019-05-10 | | Release date: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (1.14 Å) | | Cite: | Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
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1AXE | | CRYSTAL STRUCTURE OF THE ACTIVE-SITE MUTANT PHE93->TRP OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH NAD AND INHIBITOR TRIFLUOROETHANOL | | Descriptor: | ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Colby, T.D., Chin, J.K., Goldstein, B.M. | | Deposit date: | 1997-10-15 | | Release date: | 1998-04-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A link between protein structure and enzyme catalyzed hydrogen tunneling.
Proc.Natl.Acad.Sci.USA, 94, 1997
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1A2V | |
1F8N | |
1FGM | |
1FGO | |
1FGQ | |
