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1ARF
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BU of 1arf by Molmil
STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C, Xu, R.X, Horvath, S.J, Herriott, J.R, Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1ARD
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BU of 1ard by Molmil
STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C, Xu, R.X, Horvath, S.J, Herriott, J.R, Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1ARE
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BU of 1are by Molmil
STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C, Xu, R.X, Horvath, S.J, Herriott, J.R, Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1JEM
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BU of 1jem by Molmil
NMR STRUCTURE OF HISTIDINE PHOSPHORYLATED FORM OF THE PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS, NMR, 25 STRUCTURES
Descriptor: HISTIDINE CONTAINING PROTEIN
Authors:Jones, B.E, Rajagopal, P, Klevit, R.E.
Deposit date:1997-04-01
Release date:1997-07-23
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis.
Protein Sci., 6, 1997
2N0K
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BU of 2n0k by Molmil
Chemical shift assignments and structure of the alpha-crystallin domain from human, HSPB5
Descriptor: Alpha-crystallin B chain
Authors:Rajagopal, P, Klevit, R.E, Shi, L, Baker, D.
Deposit date:2015-03-09
Release date:2015-06-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis.
Elife, 4, 2015
1PAA
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BU of 1paa by Molmil
STRUCTURE OF A HISTIDINE-X4-HISTIDINE ZINC FINGER DOMAIN: INSIGHTS INTO ADR1-UAS1 PROTEIN-DNA RECOGNITION
Descriptor: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Bernstein, B.E, Hoffman, R.C, Horvath, S.J, Herriott, J.R, Klevit, R.E.
Deposit date:1994-07-15
Release date:1994-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition.
Biochemistry, 33, 1994
1BYY
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BU of 1byy by Molmil
SODIUM CHANNEL IIA INACTIVATION GATE
Descriptor: PROTEIN (SODIUM CHANNEL ALPHA-SUBUNIT)
Authors:Rohl, C.A, Boeckman, F.A, Baker, C, Scheuer, T, Catterall, W.A, Klevit, R.E.
Deposit date:1998-10-21
Release date:1999-10-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the sodium channel inactivation gate.
Biochemistry, 38, 1999
2HID
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BU of 2hid by Molmil
REFINED NMR STRUCTURE OF PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS
Descriptor: HISTIDINE CONTAINING PROTEIN
Authors:Jones, B.E, Rajagopal, P, Klevit, R.E.
Deposit date:1996-05-17
Release date:1996-11-08
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis.
Protein Sci., 6, 1997
4BVU
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BU of 4bvu by Molmil
Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate
Descriptor: PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3
Authors:Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S.
Deposit date:2013-06-28
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
4QPL
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BU of 4qpl by Molmil
Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex
Descriptor: 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), E3 ubiquitin-protein ligase RNF146, Ubiquitin-conjugating enzyme E2 D1, ...
Authors:Wang, Z, DaRosa, P.A, Klevit, R.E, Xu, W.
Deposit date:2014-06-23
Release date:2014-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.
Nature, 517, 2015
3J07
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BU of 3j07 by Molmil
Model of a 24mer alphaB-crystallin multimer
Descriptor: Alpha-crystallin B chain
Authors:Jehle, S, Vollmar, B, Bardiaux, B, Dove, K.K, Rajagopal, P, Gonen, T, Oschkinat, H, Klevit, R.E.
Deposit date:2011-04-27
Release date:2016-01-20
Last modified:2019-04-24
Method:ELECTRON MICROSCOPY (20 Å), SOLID-STATE NMR, SOLUTION SCATTERING
Cite:N-terminal domain of {alpha}B-crystallin provides a conformational switch for multimerization and structural heterogeneity.
Proc.Natl.Acad.Sci.USA, 108, 2011
7JZV
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BU of 7jzv by Molmil
Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome
Descriptor: BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ...
Authors:Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E.
Deposit date:2020-09-02
Release date:2021-02-17
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
3C5R
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BU of 3c5r by Molmil
Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences
Descriptor: BRCA1-associated RING domain protein 1
Authors:Fox III, D, Le Trong, I, Stenkamp, R.E, Klevit, R.E.
Deposit date:2008-02-01
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences.
J.Biol.Chem., 283, 2008
3UGB
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BU of 3ugb by Molmil
UbcH5c~Ubiquitin Conjugate
Descriptor: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3
Authors:Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S.
Deposit date:2011-11-02
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
3FA2
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BU of 3fa2 by Molmil
Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains
Descriptor: BRCA1-associated RING domain protein 1, GLYCEROL, PHOSPHATE ION
Authors:Fox III, D, Le Trong, I, Stenkamp, R.E, Klevit, R.E.
Deposit date:2008-11-14
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains
TO BE PUBLISHED
2KLR
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BU of 2klr by Molmil
Solid-state NMR structure of the alpha-crystallin domain in alphaB-crystallin oligomers
Descriptor: Alpha-crystallin B chain
Authors:Jehle, S, Rajagopal, P, Markovic, S, Bardiaux, B, Kuehne, R, Higman, V.A, Klevit, R.E, van Rossum, B, Oschkinat, H.
Deposit date:2009-07-08
Release date:2010-07-07
Last modified:2011-07-13
Method:SOLID-STATE NMR
Cite:Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers.
Nat.Struct.Mol.Biol., 17, 2010
2CSA
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BU of 2csa by Molmil
Structure of the M3 Muscarinic Acetylcholine Receptor Basolateral Sorting Signal
Descriptor: Muscarinic acetylcholine receptor M3
Authors:Iverson, H.A, Fox, D, Nadler, L.S, Klevit, R.E, Nathanson, N.M.
Deposit date:2005-05-21
Release date:2005-05-31
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Identification and structural determination of the M3 muscarinic acetylcholine receptor basolateral sorting signal.
J.Biol.Chem., 280, 2005
6BP9
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BU of 6bp9 by Molmil
HSPB5 alpha-crystallin domain mutant R120G-ACD
Descriptor: Alpha-crystallin B chain
Authors:Rajagopal, P, Klevit, R.E.
Deposit date:2017-11-22
Release date:2018-11-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:HSPB5 alpha-crystallin domain mutant R120G-ACD
To Be Published
1JM7
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BU of 1jm7 by Molmil
Solution structure of the BRCA1/BARD1 RING-domain heterodimer
Descriptor: BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, ZINC ION
Authors:Brzovic, P.S, Rajagopal, P, Hoyt, D.W, King, M.-C, Klevit, R.E.
Deposit date:2001-07-17
Release date:2001-10-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
Nat.Struct.Biol., 8, 2001
3DBA
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BU of 3dba by Molmil
Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C
Descriptor: Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GLYCEROL, GUANOSINE-3',5'-MONOPHOSPHATE
Authors:Martinez, S.E, Heikaus, C.C, Klevit, R.E, Beavo, J.A.
Deposit date:2008-05-30
Release date:2008-07-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change.
J.Biol.Chem., 283, 2008
6ALY
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BU of 6aly by Molmil
Solution structure of yeast Med15 ABD2 residues 277-368
Descriptor: Mediator of RNA polymerase II transcription subunit 15
Authors:Tuttle, L.M, Pacheco, D, Warfield, L, Hahn, S, Klevit, R.E.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.
Cell Rep, 22, 2018
2LPB
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BU of 2lpb by Molmil
Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15
Descriptor: General control protein GCN4, Mediator of RNA polymerase II transcription subunit 15
Authors:Brzovic, P.S, Heikaus, C.C, Kisselev, L, Vernon, R, Herbig, E, Pacheco, D, Warfield, L, Littlefield, P, Baker, D, Klevit, R.E, Hahn, S.
Deposit date:2012-02-07
Release date:2012-02-22
Method:SOLUTION NMR
Cite:The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Mol.Cell, 44, 2011
2MT6
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BU of 2mt6 by Molmil
Solution structure of the human ubiquitin conjugating enzyme Ube2w
Descriptor: Ubiquitin-conjugating enzyme E2 W
Authors:Vittal, V, Shi, L, Wenzel, D.M, Brzovic, P.S, Klevit, R.E.
Deposit date:2014-08-14
Release date:2014-11-26
Last modified:2015-01-14
Method:SOLUTION NMR
Cite:Intrinsic disorder drives N-terminal ubiquitination by Ube2w.
Nat.Chem.Biol., 11, 2015
2N3J
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BU of 2n3j by Molmil
Solution Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1
Descriptor: Heat shock protein beta-1
Authors:Rajagopal, P, Liu, Y, Shi, L, Klevit, R.E.
Deposit date:2015-06-03
Release date:2015-08-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1.
J.Biomol.Nmr, 63, 2015
2FUH
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BU of 2fuh by Molmil
Solution Structure of the UbcH5c/Ub Non-covalent Complex
Descriptor: Ubiquitin, Ubiquitin-conjugating enzyme E2 D3
Authors:Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E.
Deposit date:2006-01-26
Release date:2006-03-28
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006

 

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