Author results

1JEM
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NMR STRUCTURE OF HISTIDINE PHOSPHORYLATED FORM OF THE PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS, NMR, 25 STRUCTURES
Descriptor:HISTIDINE CONTAINING PROTEIN
Authors:Jones, B.E., Rajagopal, P., Klevit, R.E.
Deposit date:1997-04-01
Release date:1997-07-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis.
Protein Sci., 6, 1997
2HID
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REFINED NMR STRUCTURE OF PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS
Descriptor:HISTIDINE CONTAINING PROTEIN
Authors:Jones, B.E., Rajagopal, P., Klevit, R.E.
Deposit date:1996-05-17
Release date:1996-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis.
Protein Sci., 6, 1997
2N0K
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CHEMICAL SHIFT ASSIGNMENTS AND STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN FROM HUMAN, HSPB5
Descriptor:Alpha-crystallin B chain
Authors:Rajagopal, P., Klevit, R.E., Shi, L., Baker, D.
Deposit date:2015-03-09
Release date:2015-06-03
Last modified:2017-02-15
Method:SOLUTION NMR
Cite:A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis.
Elife, 4, 2015
1ARD
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STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C., Xu, R.X., Horvath, S.J., Herriott, J.R., Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1ARE
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STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C., Xu, R.X., Horvath, S.J., Herriott, J.R., Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1ARF
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STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C., Xu, R.X., Horvath, S.J., Herriott, J.R., Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1PAA
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STRUCTURE OF A HISTIDINE-X4-HISTIDINE ZINC FINGER DOMAIN: INSIGHTS INTO ADR1-UAS1 PROTEIN-DNA RECOGNITION
Descriptor:YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Bernstein, B.E., Hoffman, R.C., Horvath, S.J., Herriott, J.R., Klevit, R.E.
Deposit date:1994-07-15
Release date:1994-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition.
Biochemistry, 33, 1994
2KLR
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SOLID-STATE NMR STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN IN ALPHAB-CRYSTALLIN OLIGOMERS
Descriptor:Alpha-crystallin B chain
Authors:Jehle, S., Rajagopal, P., Markovic, S., Bardiaux, B., Kuehne, R., Higman, V.A., Klevit, R.E., van Rossum, B., Oschkinat, H.
Deposit date:2009-07-08
Release date:2010-07-07
Last modified:2011-07-13
Method:SOLID-STATE NMR
Cite:Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers.
Nat.Struct.Mol.Biol., 17, 2010
3C5R
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CRYSTAL STRUCTURE OF THE BARD1 ANKYRIN REPEAT DOMAIN AND ITS FUNCTIONAL CONSEQUENCES
Descriptor:BRCA1-associated RING domain protein 1
Authors:Fox III, D., Le Trong, I., Stenkamp, R.E., Klevit, R.E.
Deposit date:2008-02-01
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences.
J.Biol.Chem., 283, 2008
3FA2
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CRYSTAL STRUCTURE OF THE BRCA1 ASSOCIATED RING DOMAIN (BARD1) TANDEM BRCT DOMAINS
Descriptor:BRCA1-associated RING domain protein 1, PHOSPHATE ION, GLYCEROL
Authors:Fox III, D., Le Trong, I., Stenkamp, R.E., Klevit, R.E.
Deposit date:2008-11-14
Release date:2008-12-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the BRCA1 Associated Ring Domain (BARD1) Tandem BRCT Domains
TO BE PUBLISHED
3J07
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MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER
Descriptor:Alpha-crystallin B chain
Authors:Jehle, S., Vollmar, B., Bardiaux, B., Dove, K.K., Rajagopal, P., Gonen, T., Oschkinat, H., Klevit, R.E.
Deposit date:2011-04-27
Release date:2016-01-20
Last modified:2019-04-24
Method:SOLID-STATE NMR (20 Å), SOLUTION SCATTERING, ELECTRON MICROSCOPY
Cite:N-terminal domain of {alpha}B-crystallin provides a conformational switch for multimerization and structural heterogeneity.
Proc.Natl.Acad.Sci.USA, 108, 2011
4BVU
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STRUCTURE OF SHIGELLA EFFECTOR OSPG IN COMPLEX WITH HOST UBCH5C- UBIQUITIN CONJUGATE
Descriptor:PROTEIN KINASE OSPG, UBIQUITIN-CONJUGATING ENZYME E2 D3, UBIQUITIN
Authors:Pruneda, J.N., LeTrong, I., Stenkamp, R.E., Klevit, R.E., Brzovic, P.S.
Deposit date:2013-06-28
Release date:2014-01-29
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
1BYY
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SODIUM CHANNEL IIA INACTIVATION GATE
Descriptor:PROTEIN (SODIUM CHANNEL ALPHA-SUBUNIT)
Authors:Rohl, C.A., Boeckman, F.A., Baker, C., Scheuer, T., Catterall, W.A., Klevit, R.E.
Deposit date:1998-10-21
Release date:1999-10-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the sodium channel inactivation gate.
Biochemistry, 38, 1999
1JM7
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SOLUTION STRUCTURE OF THE BRCA1/BARD1 RING-DOMAIN HETERODIMER
Descriptor:BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, ZINC ION
Authors:Brzovic, P.S., Rajagopal, P., Hoyt, D.W., King, M.-C., Klevit, R.E.
Deposit date:2001-07-17
Release date:2001-10-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
Nat.Struct.Biol., 8, 2001
2CSA
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STRUCTURE OF THE M3 MUSCARINIC ACETYLCHOLINE RECEPTOR BASOLATERAL SORTING SIGNAL
Descriptor:Muscarinic acetylcholine receptor M3
Authors:Iverson, H.A., Fox, D., Nadler, L.S., Klevit, R.E., Nathanson, N.M.
Deposit date:2005-05-21
Release date:2005-05-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Identification and structural determination of the M3 muscarinic acetylcholine receptor basolateral sorting signal.
J.Biol.Chem., 280, 2005
2FUH
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SOLUTION STRUCTURE OF THE UBCH5C/UB NON-COVALENT COMPLEX
Descriptor:Ubiquitin-conjugating enzyme E2 D3, Ubiquitin
Authors:Brzovic, P.S., Lissounov, A., Hoyt, D.W., Klevit, R.E.
Deposit date:2006-01-26
Release date:2006-03-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006
2K31
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SOLUTION STRUCTURE OF CGMP-BINDING GAF DOMAIN OF PHOSPHODIESTERASE 5
Descriptor:Phosphodiesterase 5A, cGMP-specific, GUANOSINE-3',5'-MONOPHOSPHATE
Authors:Heikaus, C.C., Stout, J.R., Sekharan, M.R., Eakin, C.M., Rajagopal, P., Brzovic, P.S., Beavo, J.A., Klevit, R.E.
Deposit date:2008-04-16
Release date:2008-06-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change.
J.Biol.Chem., 283, 2008
2LPB
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STRUCTURE OF THE COMPLEX OF THE CENTRAL ACTIVATION DOMAIN OF GCN4 BOUND TO THE MEDIATOR CO-ACTIVATOR DOMAIN 1 OF GAL11/MED15
Descriptor:Mediator of RNA polymerase II transcription subunit 15, General control protein GCN4
Authors:Brzovic, P.S., Heikaus, C.C., Kisselev, L., Vernon, R., Herbig, E., Pacheco, D., Warfield, L., Littlefield, P., Baker, D., Klevit, R.E., Hahn, S.
Deposit date:2012-02-07
Release date:2012-02-22
Method:SOLUTION NMR
Cite:The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Mol.Cell, 44, 2011
2MT6
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SOLUTION STRUCTURE OF THE HUMAN UBIQUITIN CONJUGATING ENZYME UBE2W
Descriptor:Ubiquitin-conjugating enzyme E2 W
Authors:Vittal, V., Shi, L., Wenzel, D.M., Brzovic, P.S., Klevit, R.E.
Deposit date:2014-08-14
Release date:2014-11-26
Last modified:2015-01-14
Method:SOLUTION NMR
Cite:Intrinsic disorder drives N-terminal ubiquitination by Ube2w.
Nat.Chem.Biol., 11, 2015
2N3J
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SOLUTION STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN FROM THE REDOX-SENSITIVE CHAPERONE, HSPB1
Descriptor:Heat shock protein beta-1
Authors:Rajagopal, P., Liu, Y., Shi, L., Klevit, R.E.
Deposit date:2015-06-03
Release date:2015-08-19
Last modified:2015-10-14
Method:SOLUTION NMR
Cite:Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1.
J.Biomol.Nmr, 63, 2015
3DBA
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CRYSTAL STRUCTURE OF THE CGMP-BOUND GAF A DOMAIN FROM THE PHOTORECEPTOR PHOSPHODIESTERASE 6C
Descriptor:Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GUANOSINE-3',5'-MONOPHOSPHATE, GLYCEROL
Authors:Martinez, S.E., Heikaus, C.C., Klevit, R.E., Beavo, J.A.
Deposit date:2008-05-30
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change.
J.Biol.Chem., 283, 2008
3UGB
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UBCH5C~UBIQUITIN CONJUGATE
Descriptor:Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-C, GLYCEROL
Authors:Page, R.C., Pruneda, J.N., Klevit, R.E., Misra, S.
Deposit date:2011-11-02
Release date:2012-05-16
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
4QPL
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CRYSTAL STRUCTURE OF RNF146(RING-WWE)/UBCH5A/ISO-ADPR COMPLEX
Descriptor:E3 ubiquitin-protein ligase RNF146, Ubiquitin-conjugating enzyme E2 D1, 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), ...
Authors:Wang, Z., DaRosa, P.A., Klevit, R.E., Xu, W.
Deposit date:2014-06-23
Release date:2014-10-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.
Nature, 517, 2015
6ALY
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SOLUTION STRUCTURE OF YEAST MED15 ABD2 RESIDUES 277-368
Descriptor:Mediator of RNA polymerase II transcription subunit 15
Authors:Tuttle, L.M., Pacheco, D., Warfield, L., Hahn, S., Klevit, R.E.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.
Cell Rep, 22, 2018
6BP9
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HSPB5 ALPHA-CRYSTALLIN DOMAIN MUTANT R120G-ACD
Descriptor:Alpha-crystallin B chain
Authors:Rajagopal, P., Klevit, R.E.
Deposit date:2017-11-22
Release date:2018-11-28
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:HSPB5 alpha-crystallin domain mutant R120G-ACD
To Be Published
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