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1FR2
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CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A)
Descriptor:COLICIN E9 IMMUNITY PROTEIN, COLICIN E9, PHOSPHATE ION, ...
Authors:Kuhlmann, U.C., Pommer, A.J., Moore, G.M., James, R., Kleanthous, C., Hemmings, A.M.
Deposit date:2000-09-07
Release date:2003-06-17
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A)
To be Published
1FSJ
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CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN
Descriptor:COLICIN E9, PHOSPHATE ION, ZINC ION
Authors:Kuhlmann, U.C., Pommer, A.J., Moore, G.R., James, R., Kleanthous, C., Hemmings, A.M.
Deposit date:2000-09-11
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the E9 DNase domain in comparison with the inhibited structure of the E9 DNase/Im9 complex
To be Published
1IMP
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COLICIN E9 IMMUNITY PROTEIN IM9, NMR, 21 STRUCTURES
Descriptor:IM9
Authors:Osborne, M.J., Breeze, A.L., Lian, L.-Y., Reilly, A., James, R., Kleanthous, C., Moore, G.R.
Deposit date:1996-05-30
Release date:1997-09-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9.
Biochemistry, 35, 1996
1IMQ
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COLICIN E9 IMMUNITY PROTEIN IM9, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:IM9
Authors:Osborne, M.J., Breeze, A.L., Lian, L.Y., Reilly, A., James, R., Kleanthous, C., Moore, G.R.
Deposit date:1996-05-30
Release date:1997-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9.
Biochemistry, 35, 1996
1V13
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CRYSTAL STRUCTURE OF THE MUTANT HIS103ALA OF THE COLICIN E9 DNASE DOMAIN IN COMPLEX WITH ZN+2 (2.0 ANGSTROMS)
Descriptor:COLICIN E9, ZINC ION
Authors:Mate, M.J., Kleanthous, C.
Deposit date:2004-04-06
Release date:2004-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases
J.Biol.Chem., 279, 2004
1V14
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CRYSTAL STRUCTURE OF THE COLICIN E9, MUTANT HIS103ALA, IN COMPLEX WITH MG+2 AND DSDNA (RESOLUTION 2.9A)
Descriptor:COLICIN E9, 5'-D(*GP*CP*GP*AP*TP*CP*GP*CP)-3', MAGNESIUM ION
Authors:Mate, M.J., Kleanthous, C.
Deposit date:2004-04-06
Release date:2004-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases
J.Biol.Chem., 279, 2004
1V15
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CRYSTAL STRUCTURE OF THE COLICIN E9, MUTANT HIS103ALA, IN COMPLEX WITH ZN+2 AND DSDNA (RESOLUTION 2.4A)
Descriptor:COLICIN E9, 5'-D(*GP*CP*GP*AP*TP*CP*GP*CP)-3', ZINC ION
Authors:Mate, M.J., Kleanthous, C.
Deposit date:2004-04-06
Release date:2004-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-Based Analysis of the Metal-Dependent Mechanism of H-N-H Endonucleases
J.Biol.Chem., 279, 2004
2GZE
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CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9 (Y55A)
Descriptor:Colicin-E9 immunity protein, Colicin-E9, ZINC ION, ...
Authors:Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.
Deposit date:2006-05-11
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y55A)
To be Published
2GZF
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CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9 (Y54F)
Descriptor:Colicin-E9 immunity protein, Colicin-E9, ZINC ION, ...
Authors:Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.
Deposit date:2006-05-11
Release date:2007-07-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y54F)
To be Published
2GZG
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CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9 (Y55F)
Descriptor:Colicin-E9 immunity protein, Colicin-E9, ZINC ION, ...
Authors:Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.
Deposit date:2006-05-11
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y55F)
To be Published
2GZI
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CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9 (V34A)
Descriptor:Colicin-E9 immunity protein, Colicin-E9, ZINC ION, ...
Authors:Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.
Deposit date:2006-05-11
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (V34A)
To be Published
2GZJ
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CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9 (D51A)
Descriptor:Colicin-E9 immunity protein, Colicin-E9, ZINC ION, ...
Authors:Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.
Deposit date:2006-05-11
Release date:2008-03-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (D51A)
To be Published
5FRF
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SOLUTION STRUCTURE OF REDUCED AND ZINC-BOUND RSRA
Descriptor:ANTI-SIGMA FACTOR RSRA, ZINC ION
Authors:Zdanowski, K., Pecqueur, L., Werner, J., Potts, J.R., Kleanthous, C.
Deposit date:2015-12-17
Release date:2016-08-03
Method:SOLUTION NMR
Cite:The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
5FRH
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SOLUTION STRUCTURE OF OXIDISED RSRA
Descriptor:ANTI-SIGMA FACTOR RSRA
Authors:Zdanowski, K., Pecqueur, L., Werner, J., Potts, J.R., Kleanthous, C.
Deposit date:2015-12-17
Release date:2016-08-03
Method:SOLUTION NMR
Cite:The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
2IVZ
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STRUCTURE OF TOLB IN COMPLEX WITH A PEPTIDE OF THE COLICIN E9 T- DOMAIN
Descriptor:PROTEIN TOLB, COLICIN-E9, CALCIUM ION
Authors:Loftus, S.R., Walker, D., Mate, M.J., Bonsor, D.A., James, R., Moore, G.R., Kleanthous, C.
Deposit date:2006-06-23
Release date:2006-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Competitive Recruitment of the Periplasmic Translocation Portal Tolb by a Natively Disordered Domain of Colicin E9
Proc.Natl.Acad.Sci.USA, 103, 2006
4UDM
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CRYSTAL STRUCTURE OF IM3 IN COMPLEX WITH Y52A MUTANT OF E3RNASE
Descriptor:COLICIN-E3 IMMUNITY PROTEIN, COLICIN-E3, CALCIUM ION, ...
Authors:Sharma, A., Kleanthous, C.
Deposit date:2014-12-10
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Consequences of Inducing Intrinsic Disorder in a High-Affinity Protein-Protein Interaction.
J.Am.Chem.Soc., 137, 2015
4UHP
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CRYSTAL STRUCTURE OF THE PYOCIN AP41 DNASE-IMMUNITY COMPLEX
Descriptor:LARGE COMPONENT OF PYOCIN AP41, BACTERIOCIN IMMUNITY PROTEIN
Authors:Joshi, A., Chen, S., Wojdyla, J.A., Kaminska, R., Kleanthous, C.
Deposit date:2015-03-25
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa
J.Mol.Biol., 427, 2015
4UHQ
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CRYSTAL STRUCTURE OF THE PYOCIN AP41 DNASE
Descriptor:LARGE COMPONENT OF PYOCIN AP41, CITRIC ACID, NICKEL (II) ION
Authors:Joshi, A., Chen, S., Wojdyla, J.A., Kaminska, R., Kleanthous, C.
Deposit date:2015-03-25
Release date:2015-08-05
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa
J.Mol.Biol., 427, 2015
5ODW
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STRUCTURE OF THE FPVAI-PYOCIN S2 COMPLEX
Descriptor:Ferripyoverdine receptor, Pyocin-S2, SULFATE ION
Authors:White, P., Joshi, A., Kleanthous, C.
Deposit date:2017-07-06
Release date:2017-11-08
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Exploitation of an iron transporter for bacterial protein antibiotic import.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1AYI
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COLICIN E7 IMMUNITY PROTEIN IM7
Descriptor:COLICIN E IMMUNITY PROTEIN 7
Authors:Dennis, C.A., Pauptit, R.A., Wallis, R., James, R., Moore, G.R., Kleanthous, C.
Deposit date:1997-11-04
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity.
Biochem.J., 333 ( Pt 1), 1998
1E0H
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INHIBITOR PROTEIN IM9 BOUND TO ITS PARTNER E9 DNASE
Descriptor:IMMUNITY PROTEIN FOR COLICIN E9
Authors:Boetzel, R., Czisch, M., Kaptein, R., Hemmings, A.M., James, R., Kleanthous, C., Moore, G.R.
Deposit date:2000-03-28
Release date:2000-10-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Investigation of the Interaction of the Inhibitor Protein Im9 with its Partner DNase
Protein Sci., 9, 2000
1E44
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RIBONUCLEASE DOMAIN OF COLICIN E3 IN COMPLEX WITH ITS IMMUNITY PROTEIN
Descriptor:IMMUNITY PROTEIN, COLICIN E3, 1,2-ETHANEDIOL
Authors:Carr, S., Walker, D., James, R., Kleanthous, C., Hemmings, A.M.
Deposit date:2000-06-28
Release date:2001-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of a Ribosome Inactivating Ribonuclease: The Crystal Structure of the Cytotoxic Domain of Colicin E3 in Complex with its Immunity Protein
Structure, 8, 2000
1EMV
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CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS)
Descriptor:IMMUNITY PROTEIN IM9, COLICIN E9, PHOSPHATE ION
Authors:Kuhlmann, U.C., Pommer, A.J., Moore, G.M., James, R., Kleanthous, C.
Deposit date:2000-03-20
Release date:2000-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes.
J.Mol.Biol., 301, 2000
1GXG
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NON-COGNATE PROTEIN-PROTEIN INTERACTIONS: THE NMR STRUCTURE OF THE COLICIN E8 INHIBITOR PROTEIN IM8 AND ITS INTERACTION WITH THE DNASE DOMAIN OF COLICIN E9
Descriptor:COLICIN E8 IMMUNITY PROTEIN
Authors:Le Duff, C.S., Videler, H., Boetzel, R., Czisch, M., James, R., Kleanthous, C., Moore, G.R.
Deposit date:2002-04-04
Release date:2002-05-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Non-Cognate Protein-Protein Interaction: The NMR Structure of the Colicin E8 Inhibitor Protein Im8 and its Interaction with the DNase Domain of Colicin E9
To be Published
1GXH
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COLICIN E8 DNASE IMMUNITY PROTEIN: IM8
Descriptor:COLICIN E8 IMMUNITY PROTEIN
Authors:Leduff, C.S., Videler, H., Boetzel, R., Czisch, M., James, R., Kleanthous, C., Moore, G.R.
Deposit date:2002-04-05
Release date:2002-05-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Non-Cognate Protein-Protein Interaction: The NMR Structure of the Colicin E8 Inhibitor Protein Im8 and its Interaction with the DNase Domain of Colicin E9
To be Published
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