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4NTJ
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STRUCTURE OF THE HUMAN P2Y12 RECEPTOR IN COMPLEX WITH AN ANTITHROMBOTIC DRUG
Descriptor:P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, ethyl 6-{4-[(benzylsulfonyl)carbamoyl]piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate, CHOLESTEROL, ...
Authors:Zhang, K., Zhang, J., Gao, Z.-G., Zhang, D., Zhu, L., Han, G.W., Moss, S.M., Paoletta, S., Kiselev, E., Lu, W., Fenalti, G., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
Deposit date:2013-12-02
Release date:2014-03-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of the human P2Y12 receptor in complex with an antithrombotic drug
Nature, 509, 2014
4XNV
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THE HUMAN P2Y1 RECEPTOR IN COMPLEX WITH BPTU
Descriptor:P2Y purinoceptor 1, Rubredoxin, 1-[2-(2-tert-butylphenoxy)pyridin-3-yl]-3-[4-(trifluoromethoxy)phenyl]urea, ...
Authors:Zhang, D., Gao, Z., Jacobson, K., Han, G.W., Stevens, R., Zhao, Q., Wu, B., GPCR Network (GPCR)
Deposit date:2015-01-16
Release date:2015-04-01
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two disparate ligand-binding sites in the human P2Y1 receptor
Nature, 520, 2015
4XNW
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THE HUMAN P2Y1 RECEPTOR IN COMPLEX WITH MRS2500
Descriptor:P2Y purinoceptor 1,Rubredoxin,P2Y purinoceptor 1, [(1R,2S,4S,5S)-4-[2-iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hex-1-yl]methyl dihydrogen phosphate, ZINC ION
Authors:Zhang, D., Gao, Z., Jacobson, K., Han, G.W., Stevens, R., Zhao, Q., Wu, B., GPCR Network (GPCR)
Deposit date:2015-01-16
Release date:2015-04-01
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Two disparate ligand-binding sites in the human P2Y1 receptor
Nature, 520, 2015
6CA4
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CRYSTAL STRUCTURE OF HUMANIZED D. RERIO TDP2 BY 14 MUTATIONS
Descriptor:Tyrosyl-DNA phosphodiesterase 2, MAGNESIUM ION, 1,2-ETHANEDIOL, ...
Authors:Shi, K., Aihrara, H.
Deposit date:2018-01-29
Release date:2018-05-02
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.623 Å)
Cite:New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2).
Eur J Pharm Sci, 118, 2018