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2MHQ
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BU of 2mhq by Molmil
Solution structure of the major factor VIII binding region on von Willebrand factor
Descriptor: von Willebrand factor
Authors:Shiltagh, N, Kirkpatrick, J, Cabrita, L.D, McKinnon, T.A.J, Thalassinos, K, Tuddenham, E.G.D, Hansen, D.F.
Deposit date:2013-12-02
Release date:2014-05-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the major factor VIII binding region on von Willebrand factor.
Blood, 123, 2014
2MHP
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BU of 2mhp by Molmil
Solution structure of the major factor VIII binding region on von Willebrand factor
Descriptor: von Willebrand factor
Authors:Shiltagh, N, Kirkpatrick, J, Cabrita, L.D, McKinnon, T.A.J, Thalassinos, K, Tuddenham, E.G.D, Hansen, D.F.
Deposit date:2013-12-02
Release date:2014-05-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the major factor VIII binding region on von Willebrand factor.
Blood, 123, 2014
8AOU
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BU of 8aou by Molmil
Solution NMR structure of full-length Nsp1 from SARS-CoV-2.
Descriptor: Host translation inhibitor nsp1
Authors:Wang, Y, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2022-08-08
Release date:2022-12-28
Last modified:2023-02-15
Method:SOLUTION NMR
Cite:Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2.
Structure, 31, 2023
4TN3
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BU of 4tn3 by Molmil
Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha
Descriptor: TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION
Authors:Kirkpatrick, J.J, Stoye, J.P, Taylor, I.A, Goldstone, D.C.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1989 Å)
Cite:Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.
Proc.Natl.Acad.Sci.USA, 111, 2014
5I3D
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BU of 5i3d by Molmil
Sulfolobus solfataricus beta-glycosidase - E387Y mutant
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ACETATE ION, Beta-galactosidase
Authors:Iglesias-Fernandez, J, Hancock, S.M, Lee, S.S, McAuley, K.E, Fordham-Skelton, A, Rovira, C, Davis, B.D.
Deposit date:2016-02-10
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase.
Nat. Chem. Biol., 13, 2017
6ROZ
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BU of 6roz by Molmil
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based switch motif
Descriptor: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based switch motif (ITSM)
Authors:Krausze, J, Sikorska, J, Carlomagno, T.
Deposit date:2019-05-13
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6ROY
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BU of 6roy by Molmil
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif
Descriptor: Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based inhibitory motif (ITIM)
Authors:Krausze, J, Sikorska, J, Carlomagno, T.
Deposit date:2019-05-13
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6O22
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BU of 6o22 by Molmil
Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate.
Descriptor: Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ...
Authors:Danilenko, N, Carlomagno, T, Kirkpatrick, J.P.
Deposit date:2019-02-22
Release date:2019-07-31
Last modified:2019-08-14
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Histone chaperone exploits intrinsic disorder to switch acetylation specificity.
Nat Commun, 10, 2019
6R5G
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BU of 6r5g by Molmil
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
Descriptor: ITSM, Tyrosine-protein phosphatase non-receptor type 11
Authors:Marasco, M.
Deposit date:2019-03-25
Release date:2020-02-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
6F0Y
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BU of 6f0y by Molmil
Rtt109 peptide bound to Asf1
Descriptor: Histone chaperone ASF1, histone acetyltransferase Rtt109 C-terminus
Authors:Lercher, L, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2017-11-21
Release date:2017-12-27
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Structural characterization of the Asf1-Rtt109 interaction and its role in histone acetylation.
Nucleic Acids Res., 46, 2018
4PYW
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BU of 4pyw by Molmil
1.92 angstrom crystal structure of A1AT:TTAI ternary complex
Descriptor: ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL
Authors:Nyon, M.P, Day, J, Gooptu, B.
Deposit date:2014-03-28
Release date:2015-06-10
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Protein Sci., 24, 2015

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