Author results

3QG6
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STRUCTURAL BASIS FOR LIGAND RECOGNITION AND DISCRIMINATION OF A QUORUM QUENCHING ANTIBODY
Descriptor:AP4-24H11 Light Chain, AP4-24H11 Heavy Chain, Agr autoinducing peptide, ...
Authors:Kirchdoerfer, R.N., Janda, J.D., Kaufmann, G.F., Wilson, I.A.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
3TWI
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VARIABLE LYMPHOCYTE RECEPTOR RECOGNITION OF THE IMMUNODOMINANT GLYCOPROTEIN OF BACILLUS ANTHRACIS SPORES
Descriptor:BclA protein, Variable lymphocyte receptor B, GLYCEROL
Authors:Kirchdoerfer, R.N., Herrin, B.R., Han, B.W., Turnbough Jr., C.L., Cooper, M.D., Wilson, I.A.
Deposit date:2011-09-21
Release date:2012-03-14
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
3TYJ
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BACILLUS COLLAGEN-LIKE PROTEIN OF ANTHRACIS P159S MUTANT
Descriptor:BclA protein
Authors:Kirchdoerfer, R.N., Herrin, B.R., Han, B.W., Turnbough Jr., C.L., Cooper, M.D., Wilson, I.A.
Deposit date:2011-09-26
Release date:2012-03-14
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
4ZTA
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EBOLA VIRUS NUCLEOPROTEIN BOUND TO VP35 CHAPERONING PEPTIDE I212121
Descriptor:Polymerase cofactor VP35,Nucleoprotein
Authors:Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
Deposit date:2015-05-14
Release date:2015-05-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ebola virus nucleoprotein bound to VP35 chaperoning peptide I212121
to be published
4ZTG
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EBOLA VIRUS NUCLEOPROTEIN BOUND TO VP35 CHAPERONING PEPTIDE P22121
Descriptor:Polymerase cofactor VP35,Nucleoprotein fusion protein
Authors:Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
Deposit date:2015-05-14
Release date:2015-05-27
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ebola virus nucleoprotein bound to VP35 chaperoning peptide P22121
to be published
4ZTI
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EBOLA VIRUS NUCLEOPROTEIN BOUND TO VP35 CHAPERONING PEPTIDE P212121
Descriptor:Polymerase cofactor VP35,Nucleoprotein
Authors:Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
Deposit date:2015-05-14
Release date:2015-05-27
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ebola virus nucleoprotein bound to VP35 chaperoning peptide P212121
to be published
5I08
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PREFUSION STRUCTURE OF A HUMAN CORONAVIRUS SPIKE PROTEIN
Descriptor:Spike glycoprotein, envelope glycoprotein chimera
Authors:Kirchdoerfer, R.N., Cottrell, C.A., Wang, N., Pallesen, J., Yassine, H.M., Turner, H.L., Corbett, K.S., Graham, B.S., McLellan, J.S., Ward, A.B.
Deposit date:2016-02-03
Release date:2016-03-02
Last modified:2016-04-13
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Pre-fusion structure of a human coronavirus spike protein.
Nature, 531, 2016
5T3T
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EBOLA VIRUS VP30 CTD BOUND TO NUCLEOPROTEIN
Descriptor:Fusion protein of Nucleoprotein and Minor nucleoprotein VP30, SULFATE ION
Authors:Kirchdoerfer, R.N., Moyer, C.L., Abelson, D.M., Saphire, E.O.
Deposit date:2016-08-26
Release date:2016-09-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.
Plos Pathog., 12, 2016
6CRV
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, C3 SYMMETRY
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRW
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, SINGLE UPWARDS S1 CTD CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRX
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, TWO S1 CTDS IN THE UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRZ
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, C3 SYMMETRY
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS0
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, ONE S1 CTD IN AN UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS1
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, TWO S1 CTDS IN AN UPWARDS CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS2
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SARS SPIKE GLYCOPROTEIN - HUMAN ACE2 COMPLEX, STABILIZED VARIANT, ALL ACE2-BOUND PARTICLES
Descriptor:Spike glycoprotein,Fibritin, Angiotensin-converting enzyme 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6NUR
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SARS-CORONAVIRUS NSP12 BOUND TO NSP7 AND NSP8 CO-FACTORS
Descriptor:NSP12, NSP8, NSP7, ...
Authors:Kirchdoerfer, R.N., Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-29
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NUS
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SARS-CORONAVIRUS NSP12 BOUND TO NSP8 CO-FACTOR
Descriptor:NSP12, NSP8, ZINC ION
Authors:Kirchdoerfer, R.N., Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-29
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NUT
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EBOLA VIRUS NUCLEOPROTEIN - RNA COMPLEX
Descriptor:Nucleoprotein, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3')
Authors:Kirchdoerfer, R.N., Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-01
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex
Acta Crystallogr.,Sect.F, 75, 2019
2OP4
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CRYSTAL STRUCTURE OF QUORUM-QUENCHING ANTIBODY 1G9
Descriptor:Murine Antibody Fab RS2-1G9 Lambda Light Chain, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, 1,2-ETHANEDIOL
Authors:Kirchdoerfer, R.N., Debler, E.W., Wilson, I.A.
Deposit date:2007-01-26
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2YMN
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ORGANIZATION OF THE INFLUENZA VIRUS REPLICATION MACHINERY
Descriptor:NUCLEOPROTEIN
Authors:Moeller, A., Kirchdoerfer, R.N., Potter, C.S., Carragher, B., Wilson, I.A.
Deposit date:2012-10-09
Release date:2012-12-05
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Organization of the Influenza Virus Replication Machinery.
Science, 338, 2012
5TOH
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CRYSTAL STRUCTURE OF THE MARBURG VIRUS VP35 OLIGOMERIZATION DOMAIN I2
Descriptor:Polymerase cofactor VP35
Authors:Bruhn, J.F., Kirchdoerfer, R.N., Tickle, I.J., Bricogne, G., Saphire, E.O.
Deposit date:2016-10-17
Release date:2016-11-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal Structure of the Marburg Virus VP35 Oligomerization Domain.
J. Virol., 91, 2017
6BP2
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THERAPEUTIC HUMAN MONOCLONAL ANTIBODY MR191 BOUND TO A MARBURGVIRUS GLYCOPROTEIN
Descriptor:Envelope glycoprotein, Envelope glycoprotein GP2, MR191 Fab Heavy Chain, ...
Authors:King, L.B., Fusco, M.L., Flyak, A.I., Ilinykh, P.A., Huang, K., Gunn, B., Kirchdoerfer, R.N., Hastie, K.M., Sangha, A.K., Meiler, J., Alter, G., Bukreyev, A., Crowe, J.E.J., Saphire, E.O.
Deposit date:2017-11-21
Release date:2018-01-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.172 Å)
Cite:The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Cell Host Microbe, 23, 2018
3QG7
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STRUCTURAL BASIS FOR LIGAND RECOGNITION AND DISCRIMINATION OF A QUORUM QUENCHING ANTIBODY
Descriptor:AP4-24H11 Antibody Heavy Chain, AP4-24H11 Antibody Light Chain, HEXAETHYLENE GLYCOL, ...
Authors:Kirchdoerfer, R.K., Kaufmann, G.F., Janda, J.D., Wilson, I.A.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
5T3W
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MARBURG VIRUS VP30 BOUND TO NUCLEOPROTEIN
Descriptor:Fusion protein of Nucleoprotein and Minor nucleoprotein VP30
Authors:Kirchdoerfer, R.K., Moyer, C.L., Abelson, D.M., Saphire, E.O.
Deposit date:2016-08-26
Release date:2016-09-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.
Plos Pathog., 12, 2016
2NTF
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CRYSTAL STRUCTURE OF A QUORUM-QUENCHING ANTIBODY IN COMPLEX WITH AN N-ACYL-L-HOMOSERINE LACTONE ANALOG
Descriptor:Murine Antibody Fab RS2-1G9 Lambda Light Chain, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE
Authors:Debler, E.W., Wilson, I.A.
Deposit date:2006-11-07
Release date:2007-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
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