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4ESW
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CRYSTAL STRUCTURE OF C. ALBICANS THI5 H66G MUTANT
Descriptor:Pyrimidine biosynthesis enzyme THI13, CITRIC ACID
Authors:Fenwick, M.K., Huang, S., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
4ESX
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CRYSTAL STRUCTURE OF C. ALBICANS THI5 COMPLEXED WITH PLP
Descriptor:Pyrimidine biosynthesis enzyme THI13
Authors:Huang, S., Fenwick, M.K., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
1J58
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CRYSTAL STRUCTURE OF OXALATE DECARBOXYLASE
Descriptor:YVRK PROTEIN, MANGANESE (II) ION, MAGNESIUM ION, ...
Authors:Anand, R., Dorrestein, P.C., Kinsland, C., Begley, T.P., Ealick, S.E.
Deposit date:2002-02-25
Release date:2002-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of oxalate decarboxylase from Bacillus subtilis at 1.75 A resolution.
Biochemistry, 41, 2002
1L3J
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CRYSTAL STRUCTURE OF OXALATE DECARBOXYLASE FORMATE COMPLEX
Descriptor:YVRK PROTEIN, MANGANESE (II) ION, MAGNESIUM ION, ...
Authors:Anand, R., Dorrestein, P.C., Kinsland, C., Begley, T.P., Ealick, S.E.
Deposit date:2002-02-27
Release date:2002-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of oxalate decarboxylase from Bacillus subtilis at 1.75 A resolution.
Biochemistry, 41, 2002
1TLU
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CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA S-ADENOSYLMETHIONINE DECARBOXYLASE
Descriptor:S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SamDC
Authors:Toms, A.V., Kinsland, C., McCloskey, D.E., Pegg, A.E., Ealick, S.E.
Deposit date:2004-06-09
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Evolutionary Links as Revealed by the Structure of Thermotoga maritima S-Adenosylmethionine Decarboxylase.
J.Biol.Chem., 279, 2004
1TMI
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STRUCTURE OF THERMOTOGA MARITIMA S63A NON-PROCESSING MUTANT S-ADENOSYLMETHIONINE DECARBOXYLASE
Descriptor:S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SamDC
Authors:Toms, A.V., Kinsland, C., McCloskey, D.E., Pegg, A.E., Ealick, S.E.
Deposit date:2004-06-10
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evolutionary Links as Revealed by the Structure of Thermotoga maritima S-Adenosylmethionine Decarboxylase.
J.Biol.Chem., 279, 2004
3C9R
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AATHIL COMPLEXED WITH ATP
Descriptor:Thiamine monophosphate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:McCulloch, K.M., Kinsland, C., Begley, T.P., Ealick, S.E.
Deposit date:2008-02-18
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
3C9S
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AATHIL COMPLEXED WITH AMPPCP
Descriptor:Thiamine monophosphate kinase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:McCulloch, K.M., Kinsland, C., Begley, T.P., Ealick, S.E.
Deposit date:2008-02-18
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
3C9T
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AATHIL COMPLEXED WITH AMPPCP AND TMP
Descriptor:Thiamine monophosphate kinase, MAGNESIUM ION, THIAMIN PHOSPHATE, ...
Authors:McCulloch, K.M., Kinsland, C., Begley, T.P., Ealick, S.E.
Deposit date:2008-02-18
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
3C9U
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AATHIL COMPLEXED WITH ADP AND TPP
Descriptor:Thiamine monophosphate kinase, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ...
Authors:McCulloch, K.M., Kinsland, C., Begley, T.P., Ealick, S.E.
Deposit date:2008-02-18
Release date:2008-03-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural studies of thiamin monophosphate kinase in complex with substrates and products.
Biochemistry, 47, 2008
1DBT
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CRYSTAL STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM BACILLUS SUBTILIS COMPLEXED WITH UMP
Descriptor:OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE
Authors:Appleby, T.C., Kinsland, C.L., Begley, T.P., Ealick, S.E.
Deposit date:1999-11-03
Release date:2000-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure and mechanism of orotidine 5'-monophosphate decarboxylase.
Proc.Natl.Acad.Sci.USA, 97, 2000
2QQC
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E109Q MUTANT OF PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE FROM METHANOCOCCUS JANNASHII
Descriptor:Pyruvoyl-dependent arginine decarboxylase (EC 4.1.1.19) (PvlArgDC), AGMATINE, PYRUVIC ACID, ...
Authors:Ealick, S.E., Soriano, E.S.
Deposit date:2007-07-26
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
2QQD
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N47A MUTANT OF PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE FROM METHANOCOCCUS JANNASHII
Descriptor:Pyruvoyl-dependent arginine decarboxylase (EC 4.1.1.19) (PvlArgDC), AGMATINE, PYRUVIC ACID, ...
Authors:Ealick, S.E., Soriano, E.S.
Deposit date:2007-07-26
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
2THI
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THIAMINASE I FROM BACILLUS THIAMINOLYTICUS
Descriptor:THIAMINASE I, SULFATE ION
Authors:Campobasso, N., Begley, T.P., Ealick, S.E.
Deposit date:1998-09-17
Release date:1999-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of thiaminase-I from Bacillus thiaminolyticus at 2.0 A resolution.
Biochemistry, 37, 1998
3THI
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THIAMINASE I FROM BACILLUS THIAMINOLYTICUS
Descriptor:PROTEIN (THIAMINASE I), SULFATE ION
Authors:Campobasso, N., Begley, T.P., Ealick, S.E.
Deposit date:1998-10-04
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of thiaminase-I from Bacillus thiaminolyticus at 2.0 A resolution.
Biochemistry, 37, 1998
4N6E
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CRYSTAL STRUCTURE OF AMYCOLATOPSIS ORIENTALIS BEXX/CYSO COMPLEX
Descriptor:Putative thiosugar synthase, ThiS/MoaD family protein, SULFATE ION
Authors:Zhang, X., Zhang, Y., Kinsland, C., Sasaki, E., Sun, H.G., Lu, M.J., Liu, T., Ou, A., Li, J., Chen, Y., Liu, H., Ealick, S.E.
Deposit date:2013-10-11
Release date:2014-05-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
4N6F
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CRYSTAL STRUCTURE OF AMYCOLATOPSIS ORIENTALIS BEXX COMPLEXED WITH G6P
Descriptor:Putative thiosugar synthase, CALCIUM ION, FRUCTOSE -6-PHOSPHATE
Authors:Zhang, X., Zhang, Y., Kinsland, C., Sasaki, E., Sun, H.G., Lu, M.J., Liu, T., Ou, A., Li, J., Chen, Y., Liu, H., Ealick, S.E.
Deposit date:2013-10-11
Release date:2014-05-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
4THI
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THIAMINASE I FROM BACILLUS THIAMINOLYTICUS WITH COVALENTLY BOUND 4-AMINO-2,5-DIMETHYLPYRIMIDINE
Descriptor:PROTEIN (THIAMINASE I), SULFATE ION, 2,5-DIMETHYL-PYRIMIDIN-4-YLAMINE
Authors:Campobasso, N., Begley, T.P., Ealick, S.E.
Deposit date:1998-10-05
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of thiaminase-I from Bacillus thiaminolyticus at 2.0 A resolution.
Biochemistry, 37, 1998
1ESJ
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CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S)
Descriptor:HYDROXYETHYLTHIAZOLE KINASE, SULFATE ION
Authors:Campobasso, N., Mathews, I.I., Begley, T.P., Ealick, S.E.
Deposit date:2000-04-10
Release date:2000-08-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
1ESQ
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CRYSTAL STRUCTURE OF THIAZOLE KINASE MUTANT (C198S) WITH ATP AND THIAZOLE PHOSPHATE.
Descriptor:HYDROXYETHYLTHIAZOLE KINASE, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Campobasso, N., Mathews, I.I., Begley, T.P., Ealick, S.E.
Deposit date:2000-04-10
Release date:2000-08-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
1UW8
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CRYSTAL STRUCTURE OF OXALATE DECARBOXYLASE
Descriptor:OXALATE DECARBOXYLASE OXDC, MANGANESE (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Just, V.J., Stevenson, C.E.M., Bowater, L., Tanner, A., Lawson, D.M., Bornemann, S.
Deposit date:2004-02-02
Release date:2004-02-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Closed Conformation of Bacillus Subtilis Oxalate Decarboxylase Oxdc Provides Evidence for the True Identity of the Active Site
J.Biol.Chem., 279, 2004