6N7U
 
 | | apo-BDBV223 Fab | | Descriptor: | BDBV223 antibody heavy chain, BDBV223 antibody light chain | | Authors: | King, L.B, West, B.R, Saphire, E.O. | | Deposit date: | 2018-11-28 | | Release date: | 2019-03-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk.
Nat Commun, 10, 2019
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6N7J
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6BP2
 | | Therapeutic human monoclonal antibody MR191 bound to a marburgvirus glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Envelope glycoprotein GP2, ... | | Authors: | King, L.B, Fusco, M.L, Flyak, A.I, Ilinykh, P.A, Huang, K, Gunn, B, Kirchdoerfer, R.N, Hastie, K.M, Sangha, A.K, Meiler, J, Alter, G, Bukreyev, A, Crowe, J.E.J, Saphire, E.O. | | Deposit date: | 2017-11-21 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.172 Å) | | Cite: | The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Cell Host Microbe, 23, 2018
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6EA5
 | | Structure of BDBV GPcl in complex with the pan-ebolavirus mAb ADI-15878 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-15878 Fab Heavy Chain, ... | | Authors: | King, L.B, West, B.R, Moyer, C.L, Fusco, M.L, Milligan, J.C, Hui, S, Saphire, E.O. | | Deposit date: | 2018-08-02 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (4.75 Å) | | Cite: | Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope.
MBio, 9, 2018
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3T5N
 | | 1.8A crystal structure of Lassa virus nucleoprotein in complex with ssRNA | | Descriptor: | NICKEL (II) ION, Nucleoprotein, RNA (5'-R(P*UP*AP*UP*CP*UP*C)-3') | | Authors: | Hastie, K.M, Liu, T, King, L.B, Ngo, N, Zandonatti, M.A, Woods, V.L, de la Torre, J.C, Saphire, E.O. | | Deposit date: | 2011-07-27 | | Release date: | 2012-01-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.787 Å) | | Cite: | Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3T5Q
 | | 3A structure of Lassa virus nucleoprotein in complex with ssRNA | | Descriptor: | Nucleoprotein, PHOSPHATE ION, RNA (5'-R(P*UP*AP*UP*CP*UP*C)-3'), ... | | Authors: | Hastie, K.M, Liu, T, King, L.B, Ngo, N, Zandonatti, M.A, Woods, V.L, de la Torre, J.C, Saphire, E.O. | | Deposit date: | 2011-07-27 | | Release date: | 2012-01-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6EA7
 | | Structure of EBOV GPcl in complex with the pan-ebolavirus mAb ADI-15878 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | West, B.R, Moyer, C.L, King, L.B, Fusco, M.L, Milligan, J.C, Hui, S, Saphire, E.O. | | Deposit date: | 2018-08-02 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (4.25 Å) | | Cite: | Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope.
MBio, 9, 2018
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4FVU
 | | Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease | | Descriptor: | MAGNESIUM ION, Nucleoprotein, RNA (5'-R(*CP*UP*CP*CP*CP*UP*CP*C)-3'), ... | | Authors: | Hastie, K.M, King, L.B, Zandonatti, M.A, Saphire, E.O. | | Deposit date: | 2012-06-29 | | Release date: | 2012-09-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Structural Basis for the dsRNA Specificity of the Lassa Virus NP Exonuclease.
Plos One, 7, 2012
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2Y6S
 | | Structure of an Ebolavirus-protective antibody in complex with its mucin-domain linear epitope | | Descriptor: | ENVELOPE GLYCOPROTEIN, HEAVY CHAIN, LIGHT CHAIN | | Authors: | Olal, D.O, Kuehne, A, Lee, J.E, Bale, S, Dye, J.M, Saphire, E.O. | | Deposit date: | 2011-01-25 | | Release date: | 2012-01-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of an Ebola Virus-Protective Antibody in Complex with its Mucin-Domain Linear Epitope.
J.Virol., 86, 2012
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