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6AZZ
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BU of 6azz by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190
Descriptor: 1190 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-13
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0E
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BU of 6b0e by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260
Descriptor: 1260 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0G
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BU of 6b0g by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245
Descriptor: 1245 Antibody, Heavy Chain, Light Chain, ...
Authors:McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0A
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BU of 6b0a by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269
Descriptor: 1269 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B08
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BU of 6b08 by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1276
Descriptor: 1276 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0H
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BU of 6b0h by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262
Descriptor: 1,2-ETHANEDIOL, 1262 antibody, heavy chain, ...
Authors:McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
7UNB
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BU of 7unb by Molmil
Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-117 and RUPA-47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-117 Fab heavy chain, ...
Authors:Hailemariam, S, McLeod, B, Julien, J.-P.
Deposit date:2022-04-10
Release date:2022-08-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
Immunity, 55, 2022
7UXL
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BU of 7uxl by Molmil
Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-44 and RUPA-29
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-29 Fab Heavy chain, ...
Authors:Hailemariam, S, Ivanochko, D, Julien, J.P.
Deposit date:2022-05-05
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Immunity, 56, 2023
6E62
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BU of 6e62 by Molmil
Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody 85RF45.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 85RF45.1 Fab heavy chain, 85RF45.1 Fab light chain, ...
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
6E63
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BU of 6e63 by Molmil
Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody TB31F
Descriptor: GLYCEROL, Pf48/45, TB31F Fab heavy chain, ...
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
6E65
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BU of 6e65 by Molmil
Crystal structure of malaria transmission-blocking antibody TB31F
Descriptor: TB31F Fab heavy chain, TB31F Fab light chain
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
6E64
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BU of 6e64 by Molmil
Crystal structure of malaria transmission-blocking antibody 85RF45.1
Descriptor: 85RF45.1 Fab heavy chain, 85RF45.1 Fab light chain
Authors:Kundu, P, Semesi, A, Julien, J.P.
Deposit date:2018-07-23
Release date:2018-11-28
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
8EKF
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BU of 8ekf by Molmil
X-ray crystal structure of 311R Fab in complex with the PfCSP peptide NPNA-3
Descriptor: 311R Heavy Chain, 311R Light Chain, PfCSP peptide NPNA-3
Authors:Moskovitz, R, Wilson, I.A.
Deposit date:2022-09-20
Release date:2022-10-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
6PHF
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BU of 6phf by Molmil
Pfs25 in complex with the human transmission blocking antibody 2587
Descriptor: 25 kDa ookinete surface antigen, 2587 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHH
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BU of 6phh by Molmil
Unliganded human transmission blocking antibody 2544
Descriptor: 2544 Antibody Fab, Heavy Chain, Light Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PBW
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BU of 6pbw by Molmil
Crystal structure of Fab667 complex
Descriptor: Fab667 heavy chain, Fab667 light chain, GLYCEROL, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2019-06-14
Release date:2020-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.058 Å)
Cite:Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
6PHC
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BU of 6phc by Molmil
Pfs25 in complex with the human transmission blocking antibody 2544
Descriptor: 25 kDa ookinete surface antigen, 2544 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHB
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BU of 6phb by Molmil
Pfs25 in complex with the human transmission blocking antibody 2530
Descriptor: 1,2-ETHANEDIOL, 25 kDa ookinete surface antigen, 2530 Antibody Fab, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHG
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BU of 6phg by Molmil
Predicted germline variant of human transmission blocking antibody 2544
Descriptor: GLYCEROL, Germline 2544 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PBV
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BU of 6pbv by Molmil
Crystal structure of Fab668 complex
Descriptor: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2019-06-14
Release date:2020-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.566 Å)
Cite:Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
6PHD
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BU of 6phd by Molmil
Pfs25 in complex with the human transmission blocking antibody 2586
Descriptor: 25 kDa ookinete surface antigen, 2586 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
4JM2
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BU of 4jm2 by Molmil
Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab
Descriptor: 17b Heavy chain, 17b Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kong, L, Wilson, I.A.
Deposit date:2013-03-13
Release date:2013-05-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nat.Struct.Mol.Biol., 20, 2013
4JM4
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BU of 4jm4 by Molmil
Crystal Structure of PGT 135 Fab
Descriptor: PGT 135 Heavy Chain, PGT 135 Light Chain
Authors:Kong, L, Wilson, I.A.
Deposit date:2013-03-13
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nat.Struct.Mol.Biol., 20, 2013
7RXJ
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BU of 7rxj by Molmil
Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.345 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXP
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BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022

 

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