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8JZJ
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BU of 8jzj by Molmil
E.coli Glyceraldehyde-3-phosphate dehydrogenase structure under cryoprotect condition of ammonium sulfate
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION
Authors:Jang, K, Hlaing, S.H.S, Kim, H.G, Kim, N, Choe, H.W, Kim, Y.J.
Deposit date:2023-07-05
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:E.coli Glyceraldehyde-3-phosphate dehydrogenase structure under cryoprotect condition of ammonium sulfate
To Be Published
4R3R
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BU of 4r3r by Molmil
Crystal structures of EGFR in complex with Mig6
Descriptor: Epidermal growth factor receptor, peptide from ERBB receptor feedback inhibitor 1'
Authors:Park, E, Kim, N, Yi, Z, Cho, A, Kim, K, Ficarro, S.B, Park, A, Park, W.Y, Murray, B, Meyerson, M, Beroukim, R, Marto, J.A, Cho, J, Eck, M.J.
Deposit date:2014-08-17
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.
Nat.Struct.Mol.Biol., 22, 2015
4R3P
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BU of 4r3p by Molmil
Crystal structures of EGFR in complex with Mig6
Descriptor: Epidermal growth factor receptor, peptide from ERBB receptor feedback inhibitor 1
Authors:Park, E, Kim, N, Yi, Z, Cho, A, Kim, K, Ficarro, S.B, Park, A, Park, W.Y, Murray, B, Meyerson, M, Beroukim, R, Marto, J.A, Cho, J, Eck, M.J.
Deposit date:2014-08-17
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.905 Å)
Cite:Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.
Nat.Struct.Mol.Biol., 22, 2015
2MHI
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BU of 2mhi by Molmil
Solution structure of the CR4/5 domain of medaka telomerase RNA
Descriptor: Medaka telomerase RNA
Authors:Kim, N, Zhang, Q, Feigon, J.
Deposit date:2013-11-23
Release date:2013-12-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function.
Nucleic Acids Res., 42, 2014
7MSO
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BU of 7mso by Molmil
Crystal Structure of Polo Box Domain in Complex with Cyclic Peptide Inhibitor
Descriptor: Cyclic Peptide Inhibitor ZO1-GLN-SER-TPO-45W-MLL, Serine/threonine-protein kinase PLK1
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2021-05-11
Release date:2022-03-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1.
J.Med.Chem., 65, 2022
4ZJV
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BU of 4zjv by Molmil
crystal structure of EGFR kinase domain in complex with Mitogen-inducible gene 6 protein
Descriptor: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
Authors:Eck, M.J, Park, E, Lee, B.
Deposit date:2015-04-29
Release date:2015-08-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.
Nat.Struct.Mol.Biol., 22, 2015
8J0H
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BU of 8j0h by Molmil
Crystal structure of the fission yeast Rex1BD protein(C4H3.06)
Descriptor: Uncharacterized protein C4H3.06
Authors:Li, J, Sun, W, Chen, Y.
Deposit date:2023-04-11
Release date:2023-11-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.383 Å)
Cite:Crystal structure of the fission yeast Rex1BD protein(C4H3.06)
To Be Published
4GQZ
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BU of 4gqz by Molmil
Crystal Structure of S.CueP
Descriptor: CHLORIDE ION, Putative periplasmic or exported protein
Authors:Ha, N.C, Yoon, B.Y.
Deposit date:2012-08-24
Release date:2013-08-14
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structure of the periplasmic copper-binding protein CueP from Salmonella enterica serovar Typhimurium
Acta Crystallogr.,Sect.D, 69, 2013
4ML7
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BU of 4ml7 by Molmil
Crystal structure of Brucella abortus PliC in complex with human lysozyme
Descriptor: Humanlysozyme, Lysozyme C
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-06
Release date:2014-07-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Inhibition of Human Lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
4MIR
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BU of 4mir by Molmil
The structure of Brucella abortus PliC in the hexagonal crystal form
Descriptor: Putative uncharacterized protein
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-02
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the inhibition of human lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
4MIS
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BU of 4mis by Molmil
The structure of Brucella abortus PliC in the orthorombic crystal form
Descriptor: Putative uncharacterized protein
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-02
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of human lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
4R5S
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BU of 4r5s by Molmil
Crystal structure of EGFR 696-1022 L858R in complex with FIIN-3
Descriptor: Epidermal growth factor receptor, N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide
Authors:Zhu, S.J, Yun, C.H.
Deposit date:2014-08-22
Release date:2014-11-12
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QQC
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BU of 4qqc by Molmil
Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations
Descriptor: Fibroblast growth factor receptor 4, N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide, SULFATE ION
Authors:Huang, Z, Mohammadi, M.
Deposit date:2014-06-27
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
4R6V
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BU of 4r6v by Molmil
Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex with FIIN-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR kinase Gate-Keeper Mutations
Descriptor: Fibroblast growth factor receptor 4, N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide, SULFATE ION
Authors:Huang, Z, Mohammadi, M.
Deposit date:2014-08-26
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
7V6H
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BU of 7v6h by Molmil
Crystal Structure of the SpnL
Descriptor: Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Wu, H.-H, Ko, T.-P, Liu, H.-W, Tsai, M.-D.
Deposit date:2021-08-20
Release date:2021-12-29
Method:X-RAY DIFFRACTION (3.054 Å)
Cite:Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A.
J.Am.Chem.Soc., 143, 2021
2L3E
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BU of 2l3e by Molmil
Solution structure of P2a-J2a/b-P2b of human telomerase RNA
Descriptor: 35-MER
Authors:Zhang, Q, Kim, N, Peterson, R.D, Wang, Z, Feigon, J.
Deposit date:2010-09-13
Release date:2010-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Inaugural Article: Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
2M8K
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BU of 2m8k by Molmil
A pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo
Descriptor: RNA (48-MER)
Authors:Cash, D.D, Cohen, O, Kim, N, Shefer, K, Brown, Y, Ulyanov, N.B, Tzfati, Y, Feigon, J.
Deposit date:2013-05-22
Release date:2013-06-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
1IBQ
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BU of 1ibq by Molmil
ASPERGILLOPEPSIN FROM ASPERGILLUS PHOENICIS
Descriptor: ASPERGILLOPEPSIN, ZINC ION, alpha-D-mannopyranose
Authors:Cho, S.W, Shin, W.
Deposit date:2001-03-28
Release date:2001-07-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure of aspergillopepsin I from Aspergillus phoenicis: variations of the S1'-S2 subsite in aspartic proteinases.
Acta Crystallogr.,Sect.D, 57, 2001
3V6S
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BU of 3v6s by Molmil
Discovery of potent and selective covalent inhibitors of JNK
Descriptor: 3-{[4-(dimethylamino)butanoyl]amino}-N-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
Authors:Park, H, Laughlin, J.D, LoGrasso, P.V.
Deposit date:2011-12-20
Release date:2012-02-01
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
3V6R
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BU of 3v6r by Molmil
Discovery of potent and selective covalent inhibitors of JNK
Descriptor: 4-{[4-(dimethylamino)butanoyl]amino}-N-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
Authors:Park, H, LoGrasso, P.V, Laughlin, J.D.
Deposit date:2011-12-20
Release date:2012-02-01
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
3LWG
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BU of 3lwg by Molmil
Crystal structure of HP0420-homologue C46A from helicobacter felis
Descriptor: HP0420 homologue
Authors:Ha, N.-C, Piao, S.
Deposit date:2010-02-23
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure and functional insight of HP0420-homolog from Helicobacter felis
Biochem.Biophys.Res.Commun., 394, 2010
3LW3
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BU of 3lw3 by Molmil
Crystal structure of HP0420-homologue from Helicobacter felis
Descriptor: HP0420 homologue
Authors:Ha, N.-C, Piao, S.
Deposit date:2010-02-23
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure and functional insight of HP0420-homolog from Helicobacter felis
Biochem.Biophys.Res.Commun., 394, 2010
1WZ9
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BU of 1wz9 by Molmil
The 2.1 A structure of a tumour suppressing serpin
Descriptor: Maspin precursor, SULFATE ION
Authors:Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C.
Deposit date:2005-03-03
Release date:2005-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
1XU8
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BU of 1xu8 by Molmil
The 2.8 A structure of a tumour suppressing serpin
Descriptor: Maspin, SULFATE ION
Authors:Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C.
Deposit date:2004-10-25
Release date:2005-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005

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