Author results

1A1R
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HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX
Descriptor:NS3 PROTEIN, NS4A PROTEIN, ZINC ION
Authors:Kim, J.L., Morgenstern, K.A., Lin, C., Fox, T., Dwyer, M.D., Landro, J.A., Chambers, S.P., Markland, W., Lepre, C.A., O'Malley, E.T., Harbeson, S.L., Rice, C.M., Murcko, M.A., Caron, P.R., Thomson, J.A.
Deposit date:1997-12-15
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.
Cell(Cambridge,Mass.), 87, 1996
1A1V
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HEPATITIS C VIRUS NS3 HELICASE DOMAIN COMPLEXED WITH SINGLE STRANDED SDNA
Descriptor:DNA (5'-D(*UP*UP*UP*UP*UP*UP*UP*U)-3'), PROTEIN (NS3 PROTEIN), SULFATE ION
Authors:Kim, J.L., Morgenstern, K.A., Griffith, J.P., Dwyer, M.D., Thomson, J.A., Murcko, M.A., Lin, C., Caron, P.R.
Deposit date:1997-12-17
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding.
Structure, 6, 1998
1VTL
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CO-CRYSTAL STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF A TATA ELEMENT
Descriptor:DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA BINDING PROTEIN (TBP)
Authors:Kim, J.L., Nikolov, D.B., Burley, S.K.
Deposit date:1993-12-17
Release date:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Co-Crystal Structure of TBP Recognizing the Minor Groove of a TATA Element
Nature, 365, 1993
1VTO
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1.9 A RESOLUTION REFINED STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF TATAAAAG
Descriptor:DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA BINDING PROTEIN
Authors:Kim, J.L., Burley, S.K.
Deposit date:1996-09-06
Release date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:1.9 A Resolution Refined Structure of TBP Recognizing the Minor Groove of TATAAAAG
Nat.Struct.Biol., 1, 1994
1QNE
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CRYSTAL STRUCTURE OF THE ADENOVIRUS MAJOR LATE PROMOTER TATA BOX BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2).
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3')
Authors:Kim, J.L., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
4XCU
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CRYSTAL STRUCTURE OF FGFR4 WITH AN IRREVERSIBLE INHIBITOR
Descriptor:Fibroblast growth factor receptor 4, SULFATE ION, N-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)propanamide
Authors:Kim, J.L., Miduturu, C., Hodous, B., Brooijmans, N., Bifulco, N., Guzi, T.
Deposit date:2014-12-18
Release date:2015-04-01
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.
Cancer Discov, 5, 2015
1TCO
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TERNARY COMPLEX OF A CALCINEURIN A FRAGMENT, CALCINEURIN B, FKBP12 AND THE IMMUNOSUPPRESSANT DRUG FK506 (TACROLIMUS)
Descriptor:SERINE/THREONINE PHOSPHATASE B2, FK506-BINDING PROTEIN, ZINC ION, ...
Authors:Griffith, J.P., Kim, J.L., Kim, E.E., Sintchak, M.D., Thomson, J.A., Fitzgibbon, M.J., Fleming, M.A., Caron, P.R., Hsiao, K., Navia, M.A.
Deposit date:1996-08-21
Release date:1997-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.
Cell(Cambridge,Mass.), 82, 1995
1QN3
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CRYSTAL STRUCTURE OF THE C(-25) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*GP*TP*TP*TP*AP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QN4
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CRYSTAL STRUCTURE OF THE T(-24) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*TP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*AP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QN5
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CRYSTAL STRUCTURE OF THE G(-26) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*GP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*CP*TP*TP*AP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QN6
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CRYSTAL STRUCTURE OF THE T(-26) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*TP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*AP*TP*TP*AP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QN7
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CRYSTAL STRUCTURE OF THE T(-27) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*TP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*AP*TP*AP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QN8
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CRYSTAL STRUCTURE OF THE T(-28) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*TP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*AP*AP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QN9
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CRYSTAL STRUCTURE OF THE C(-29) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*CP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*GP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QNA
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CRYSTAL STRUCTURE OF THE T(-30) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*TP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*AP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QNB
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CRYSTAL STRUCTURE OF THE T(-25) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*TP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*AP*TP*TP*TP*AP*TP*AP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QNC
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CRYSTAL STRUCTURE OF THE A(-31) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION.
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID-1, DNA (5'-D(*GP*CP*AP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*TP*GP*C)-3')
Authors:Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T., Burley, S.K.
Deposit date:1999-10-14
Release date:2000-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution
Genes Dev., 13, 1999
1QPC
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STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS
Descriptor:Tyrosine-protein kinase Lck, SULFATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Zhu, X., Kim, J.L., Rose, P.E., Stover, D.R., Toledo, L.M., Zhao, H., Morgenstern, K.A.
Deposit date:1999-05-21
Release date:2000-05-24
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
1QPD
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STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS
Descriptor:LCK KINASE, SULFATE ION, STAUROSPORINE
Authors:Zhu, X., Kim, J.L., Rose, P.E., Stover, D.R., Toledo, L.M., Zhao, H., Morgenstern, K.A.
Deposit date:1999-05-24
Release date:2000-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
1QPJ
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CRYSTAL STRUCTURE OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH STAUROSPORINE.
Descriptor:LCK TYROSINE KINASE, SULFATE ION, STAUROSPORINE
Authors:Zhu, X., Kim, J.L., Rose, P.E., Stover, D.R., Toledo, L.M.
Deposit date:1999-05-25
Release date:2000-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
2P2H
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CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH A PYRIDINYL-TRIAZINE INHIBITOR
Descriptor:Vascular endothelial growth factor receptor 2, 4-(2-anilinopyridin-3-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine
Authors:Whittington, D.A., Kim, J.L., Long, A.M., Rose, P., Gu, Y., Zhao, H.
Deposit date:2007-03-07
Release date:2007-03-20
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor
J.Med.Chem., 50, 2007
2P2I
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CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH A NICOTINAMIDE INHIBITOR
Descriptor:Vascular endothelial growth factor receptor 2, N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide
Authors:Whittington, D.A., Kim, J.L., Long, A.M., Rose, P., Gu, Y., Zhao, H.
Deposit date:2007-03-07
Release date:2007-03-20
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor
J.Med.Chem., 50, 2007
2QU5
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CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH A BENZIMIDAZOLE INHIBITOR
Descriptor:Vascular endothelial growth factor receptor 2, 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide
Authors:Whittington, D.A., Kim, J.L., Long, A.M., Rose, P., Gu, Y., Zhao, H.
Deposit date:2007-08-03
Release date:2007-09-25
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors.
J.Med.Chem., 50, 2007
2QU6
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CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH A BENZOXAZOLE INHIBITOR
Descriptor:Vascular endothelial growth factor receptor 2, SULFATE ION, 4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-N-methylpyridine-2-carboxamide
Authors:Whittington, D.A., Kim, J.L., Long, A.M., Rose, P., Gu, Y., Zhao, H.
Deposit date:2007-08-03
Release date:2007-09-25
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors.
J.Med.Chem., 50, 2007
3DA6
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CRYSTAL STRUCTURE OF HUMAN JNK3 COMPLEXED WITH N-(3-METHYL-4-(3-(2-(METHYLAMINO)PYRIMIDIN-4-YL)PYRIDIN-2-YLOXY)NAPHTHALEN-1-YL)-1H-BENZO[D]IMIDAZOL-2-AMINE
Descriptor:Mitogen-activated protein kinase 10, N-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)naphthalen-1-yl]-1H-benzimidazol-2-amine
Authors:Cee, V.J., Cheng, A.C., Romero, K., Bellon, S., Mohr, C., Whittington, D.A., Bready, J., Caenepeel, S., Coxon, A., Deak, H.L., Hodous, B.L., Kim, J.L., Lin, J., Nguyen, H., Olivieri, P.R., Patel, V.F., Wang, L., Hughes, P., Geuns-Meyer, S.
Deposit date:2008-05-28
Release date:2009-01-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase
Bioorg.Med.Chem.Lett., 19, 2009
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