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1EJ5
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BU of 1ej5 by Molmil
SOLUTION STRUCTURE OF THE AUTOINHIBITED CONFORMATION OF WASP
Descriptor: WISKOTT-ALDRICH SYNDROME PROTEIN
Authors:Kim, A.S, Kakalis, L.T, Abdul-Manan, N, Liu, G.A, Rosen, M.K.
Deposit date:2000-02-29
Release date:2000-04-05
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.
Nature, 404, 2000
6ORT
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BU of 6ort by Molmil
Crystal Structure of Bos taurus Mxra8 Ectodomain
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Matrix remodeling-associated protein 8
Authors:Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-04-30
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
Cell Host Microbe, 27, 2020
7CW3
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BU of 7cw3 by Molmil
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex)
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CW0
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BU of 7cw0 by Molmil
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
1T84
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BU of 1t84 by Molmil
Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor
Descriptor: (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL, Wiskott-Aldrich syndrome protein
Authors:Peterson, J.R, Bickford, L.C, Morgan, D, Kim, A.S, Ouerfelli, O, Kirschner, M.W, Rosen, M.K.
Deposit date:2004-05-11
Release date:2004-07-13
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nat.Struct.Mol.Biol., 11, 2004
6MW9
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BU of 6mw9 by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody
Descriptor: E1, E2, EEEV-3 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-29
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWX
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BU of 6mwx by Molmil
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody
Descriptor: E1, E2, EEEV-69 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MUI
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BU of 6mui by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody
Descriptor: E1, E2, EEEV-42 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-23
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MX7
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BU of 6mx7 by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus: Genome-Binding Capsid N-terminal Domain
Descriptor: Capsid
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWV
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BU of 6mwv by Molmil
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-58 Antibody
Descriptor: E1, E2, EEEV-58 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MX4
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BU of 6mx4 by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-30
Release date:2018-12-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWC
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BU of 6mwc by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody
Descriptor: E1, E2, EEEV-5 antibody heavy chain, ...
Authors:Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
Deposit date:2018-10-29
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6NK3
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BU of 6nk3 by Molmil
Crystal structure of murine Mxra8 ectodomain
Descriptor: Matrix remodeling-associated protein 8
Authors:Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK7
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BU of 6nk7 by Molmil
Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.99 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK6
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BU of 6nk6 by Molmil
Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
7CW2
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BU of 7cw2 by Molmil
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 (subregion around icosahedral 5-fold vertex)
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CVZ
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BU of 7cvz by Molmil
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CVY
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BU of 7cvy by Molmil
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
8SQN
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BU of 8sqn by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ...
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-05-04
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Cell, 186, 2023
6W09
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BU of 6w09 by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, E3, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-02-29
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6W1C
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BU of 6w1c by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-03-04
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6VYV
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BU of 6vyv by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-02-27
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.33 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6W2U
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BU of 6w2u by Molmil
Mayaro Virus glycoprotein E1 ectodomain and glycoportien E2 ectodomain asymmetric unit
Descriptor: Spike glycoprotein E1, Spike glycoprotein E2
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-03-08
Release date:2020-10-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6C74
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BU of 6c74 by Molmil
Crystal Structure of Murine CD300lf in complex with phosphocholine
Descriptor: CALCIUM ION, CMRF35-like molecule-1, PHOSPHOCHOLINE
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-01-19
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.358 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C6Q
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BU of 6c6q by Molmil
Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CMRF35-like molecule 1, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-01-19
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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