1IA0
 
 | | KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, ... | | Authors: | Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. | | Deposit date: | 2001-03-22 | | Release date: | 2002-03-22 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (15 Å) | | Cite: | Switch-based Mechanism of Kinesin Motors
Nature, 411, 2001
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2HXF
 | | KIF1A head-microtubule complex structure in amppnp-form | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | | Authors: | Kikkawa, M, Hirokawa, N. | | Deposit date: | 2006-08-03 | | Release date: | 2006-10-10 | | Last modified: | 2023-03-22 | | Method: | ELECTRON MICROSCOPY (10 Å) | | Cite: | High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations
Embo J., 25, 2006
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2HXH
 | | KIF1A head-microtubule complex structure in adp-form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Kikkawa, M, Hirokawa, N. | | Deposit date: | 2006-08-03 | | Release date: | 2006-10-10 | | Last modified: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (11 Å) | | Cite: | High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations
Embo J., 25, 2006
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1I6I
 | | CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION, ... | | Authors: | Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. | | Deposit date: | 2001-03-02 | | Release date: | 2001-05-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Switch-based mechanism of kinesin motors
Nature, 411, 2001
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1I5S
 | | CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION | | Authors: | Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. | | Deposit date: | 2001-02-28 | | Release date: | 2001-05-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Switch-based mechanism of kinesin motors
Nature, 411, 2001
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7EQ9
 | | Cryo-EM structure of designed protein nanoparticle TIP60 (Truncated Icosahedral Protein composed of 60-mer fusion proteins) | | Descriptor: | TIP60 | | Authors: | Obata, J, Kawakami, N, Tsutsumi, A, Miyamoto, K, Kikkawa, M, Arai, R. | | Deposit date: | 2021-04-30 | | Release date: | 2021-09-15 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Icosahedral 60-meric porous structure of designed supramolecular protein nanoparticle TIP60.
Chem.Commun.(Camb.), 57, 2021
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2WBE
 | | Kinesin-5-Tubulin Complex with AMPPNP | | Descriptor: | BIPOLAR KINESIN KRP-130, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Bodey, A.J, Kikkawa, M, Moores, C.A. | | Deposit date: | 2009-02-26 | | Release date: | 2009-03-24 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (9.4 Å) | | Cite: | 9-Angstrom Structure of a Microtubule-Bound Mitotic Motor.
J.Mol.Biol., 388, 2009
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5HNY
 | | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the AMPPNP state | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | Deposit date: | 2016-01-19 | | Release date: | 2016-08-10 | | Last modified: | 2016-11-02 | | Method: | ELECTRON MICROSCOPY (6.3 Å) | | Cite: | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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5HNZ
 | | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the nucleotide-free state | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | Deposit date: | 2016-01-19 | | Release date: | 2016-08-10 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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5HNX
 | | Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the nucleotide-free state | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | Deposit date: | 2016-01-19 | | Release date: | 2016-08-10 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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5HNW
 | | Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the AMPPNP state | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | | Deposit date: | 2016-01-19 | | Release date: | 2016-08-10 | | Last modified: | 2018-07-25 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
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5GSY
 | | Kinesin-8 motor, KIF19A, in the nucleotide-free state complexed with GDP-taxol microtubule | | Descriptor: | Kinesin-like protein KIF19 | | Authors: | Morikawa, M, Nitta, R, Yajima, H, Shigematsu, H, Kikkawa, M, Hirokawa, N. | | Deposit date: | 2016-08-17 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A
Elife, 5, 2016
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7VMM
 | | Structure of recombinant RyR2 (EGTA dataset, class 1, closed state) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMQ
 | | Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
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7VML
 | | Structure of recombinant RyR2 (EGTA dataset, class 1&2, closed state) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMS
 | | Structure of recombinant RyR2 mutant K4593A (Ca2+ dataset) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
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7VMO
 | | Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMR
 | | Structure of recombinant RyR2 mutant K4593A (EGTA dataset) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMP
 | | Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state) | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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7VMN
 | | Structure of recombinant RyR2 (EGTA dataset, class 2, closed state) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | | Deposit date: | 2021-10-09 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
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1V5I
 | | Crystal structure of serine protease inhibitor POIA1 in complex with subtilisin BPN' | | Descriptor: | CALCIUM ION, GLYCEROL, IA-1=serine proteinase inhibitor, ... | | Authors: | Lee, W.C, Kikkawa, M, Kojima, S, Miura, K, Tanokura, M. | | Deposit date: | 2003-11-24 | | Release date: | 2005-03-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of serine protease inhibitor POIA1 in complex with subtilisin BPN'
To be Published
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8JJ5
 | | Porcine uroplakin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Tetraspanin, ... | | Authors: | Oda, T, Yanagisawa, H, Kikkawa, M. | | Deposit date: | 2023-05-29 | | Release date: | 2023-06-14 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane
Commun Biol, 6, 2023
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1VFV
 | | Crystal Structure of the Kif1A Motor Domain Complexed With Mg-AMPPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... | | Authors: | Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. | | Deposit date: | 2004-04-19 | | Release date: | 2004-08-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | KIF1A Alternately Uses Two Loops to Bind Microtubules
Science, 305, 2004
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1VFX
 | | Crystal Structure of the Kif1A Motor Domain Complexed With ADP-Mg-AlFx | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | | Authors: | Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. | | Deposit date: | 2004-04-19 | | Release date: | 2004-08-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | KIF1A Alternately Uses Two Loops to Bind Microtubules
Science, 305, 2004
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1VFW
 | | Crystal Structure of the Kif1A Motor Domain Complexed With Mg-AMPPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... | | Authors: | Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. | | Deposit date: | 2004-04-19 | | Release date: | 2004-08-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | KIF1A Alternately Uses Two Loops to Bind Microtubules
Science, 305, 2004
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