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1AJF
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BU of 1ajf by Molmil
SOLUTION STRUCTURE OF THE P5B STEM LOOP FROM A GROUP I INTRON COMPLEXED WITH COBALT (III) HEXAMMINE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: COBALT HEXAMMINE(III), RNA (5'-R(*GP*AP*CP*AP*GP*GP*GP*GP*AP*AP*AP*CP*UP*UP*UP*GP*UP*C)-3')
Authors:Kieft, J.S, Tinoco Junior, I.
Deposit date:1997-05-02
Release date:1997-07-07
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution structure of a metal-binding site in the major groove of RNA complexed with cobalt (III) hexammine.
Structure, 5, 1997
1KH6
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BU of 1kh6 by Molmil
Crystal Structure of an RNA Tertiary Domain Essential to HCV IRES-mediated Translation Initiation.
Descriptor: JIIIabc
Authors:Kieft, J.S, Zhou, K, Grech, A, Jubin, R, Doudna, J.A.
Deposit date:2001-11-29
Release date:2002-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation.
Nat.Struct.Biol., 9, 2002
3MJB
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BU of 3mjb by Molmil
Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to sulfate
Descriptor: Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SULFATE ION
Authors:Kieft, J.S, Golden, B.L, Costantino, D.A, Chase, E.
Deposit date:2010-04-12
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification and characterization of anion binding sites in RNA.
Rna, 16, 2010
3MJ3
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BU of 3mj3 by Molmil
Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to selenate
Descriptor: Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SELENATE ION
Authors:Kieft, J.S, Chase, E, Costantino, D.A, Golden, B.L.
Deposit date:2010-04-12
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification and characterization of anion binding sites in RNA.
Rna, 16, 2010
3MJA
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BU of 3mja by Molmil
Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to selenate, structure #2
Descriptor: Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SELENATE ION
Authors:Kieft, J.S, Golden, B.L, Costantino, D.A, Chase, E.
Deposit date:2010-04-12
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification and characterization of anion binding sites in RNA.
Rna, 16, 2010
3B31
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BU of 3b31 by Molmil
Crystal structure of domain III of the Cricket Paralysis Virus IRES RNA
Descriptor: IRIDIUM HEXAMMINE ION, PHOSPHATE ION, RNA (29-MER), ...
Authors:Kieft, J.S, Costantino, D.A, Pfingsten, J.S, Rambo, R.P.
Deposit date:2007-10-19
Release date:2007-12-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:tRNA-mRNA mimicry drives translation initiation from a viral IRES.
Nat.Struct.Mol.Biol., 15, 2008
7SC6
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BU of 7sc6 by Molmil
tRNA-like Structure from Brome Mosaic Virus Bound to Tyrosyl-tRNA Synthetase from Phaseolus vulgaris. Conformation: Bound State 1.
Descriptor: Tyrosine--tRNA ligase, tRNA-like structure from brome mosaic virus RNA 3
Authors:Kieft, J.S, Bonilla, S.L.
Deposit date:2021-09-27
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (5.51 Å)
Cite:A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure.
Science, 374, 2021
7SCQ
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BU of 7scq by Molmil
tRNA-like Structure from Brome Mosaic Virus Bound to Tyrosyl-tRNA Synthetase from Phaseolus vulgaris. Conformation: Bound State 2.
Descriptor: Tyrosine--tRNA ligase, tRNA-like structure from brome mosaic virus RNA 3.
Authors:Kieft, J.S, Bonilla, S.L.
Deposit date:2021-09-28
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (6 Å)
Cite:A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure.
Science, 374, 2021
7SAM
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BU of 7sam by Molmil
tRNA-like Structure from Brome Mosaic Virus
Descriptor: Viral RNA
Authors:Kieft, J.S, Bonilla, S.L.
Deposit date:2021-09-22
Release date:2021-12-01
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure.
Science, 374, 2021
7UVT
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BU of 7uvt by Molmil
Kinetically trapped misfolded state of the Tetrahymena ribozyme
Descriptor: RNA (386-MER)
Authors:Bonilla, S.L, Vicens, Q, Kieft, J.S.
Deposit date:2022-05-02
Release date:2022-08-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA.
Sci Adv, 8, 2022
4V84
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BU of 4v84 by Molmil
Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome.
Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
Deposit date:2010-12-13
Release date:2014-07-09
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
4V83
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BU of 4v83 by Molmil
Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome.
Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
Deposit date:2010-12-13
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
2IL9
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BU of 2il9 by Molmil
Crystal Structure of Plautia Stali Intestine Virus Intergenic Region Internal Ribosome Entry Site Ribosomal Binding Domain RNA at 3.1 Angstroms
Descriptor: Ribosomal Binding Domain of the IRES RNA
Authors:Pfingsten, J.S, Costantino, D.A, Kieft, J.S.
Deposit date:2006-10-02
Release date:2007-02-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for ribosome recruitment and manipulation by a viral IRES RNA
Science, 314, 2006
7KGA
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BU of 7kga by Molmil
Crystal structure of a mosquito-borne flavivirus dumbbell RNA
Descriptor: IRIDIUM HEXAMMINE ION, RNA (90-MER)
Authors:Akiyama, B.M, Graham, M.E, O'Donoghue, Z, Beckham, J.D, Kieft, J.S.
Deposit date:2020-10-16
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication.
Nucleic Acids Res., 49, 2021
8FVY
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BU of 8fvy by Molmil
40S subunit of the Giardia lamblia 80S ribosome
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ...
Authors:Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S.
Deposit date:2023-01-20
Release date:2024-01-24
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Structure, 2024
8FRU
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BU of 8fru by Molmil
60S subunit of the Giardia lamblia 80S ribosome
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S.
Deposit date:2023-01-08
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (2.49 Å)
Cite:The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Structure, 2024
8G4S
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BU of 8g4s by Molmil
40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V2 conformation with mRNA and three tRNAs.
Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ...
Authors:Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S.
Deposit date:2023-02-10
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Structure, 2024
8TJQ
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BU of 8tjq by Molmil
Tetrahymena Ribozyme scaffolded Zika Virus xrRNA
Descriptor: MAGNESIUM ION, RNA (440-MER)
Authors:Langeberg, C.J, Kieft, J.S.
Deposit date:2023-07-24
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM.
Nucleic Acids Res., 51, 2023
8TJX
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BU of 8tjx by Molmil
Tetrahymena Ribozyme cryo-EM scaffold
Descriptor: MAGNESIUM ION, RNA (440-MER)
Authors:Langeberg, C.J, Kieft, J.S.
Deposit date:2023-07-24
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM.
Nucleic Acids Res., 51, 2023
8TJU
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BU of 8tju by Molmil
Tetrahymena Ribozyme scaffolded TABV xrRNA
Descriptor: DNA/RNA (416-MER), MAGNESIUM ION
Authors:Langeberg, C.J, Kieft, J.S.
Deposit date:2023-07-24
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM.
Nucleic Acids Res., 51, 2023
8TJV
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BU of 8tjv by Molmil
Tetrahymena Ribozyme scaffolded Fluoride riboswitch
Descriptor: FLUORIDE ION, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Langeberg, C.J, Kieft, J.S.
Deposit date:2023-07-24
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM.
Nucleic Acids Res., 51, 2023
7JJU
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BU of 7jju by Molmil
Crystal structure of en exoribonuclease-resistant RNA (xrRNA) from Potato leafroll virus (PLRV)
Descriptor: CACODYLATE ION, Guanidinium, IRIDIUM HEXAMMINE ION, ...
Authors:Steckelberg, A.-L, Vicens, Q, Auffinger, P, Costantino, D.C, Nix, J.C, Kieft, J.S.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold.
Rna, 26, 2020
7K16
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BU of 7k16 by Molmil
Tamana Bat Virus xrRNA1
Descriptor: MAGNESIUM ION, RNA (51-MER), SODIUM ION
Authors:Jones, R.A, Kieft, J.S.
Deposit date:2020-09-07
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA.
Rna, 27, 2021
5TPY
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BU of 5tpy by Molmil
Crystal structure of an exonuclease resistant RNA from Zika virus
Descriptor: HEXANE-1,6-DIOL, MAGNESIUM ION, RNA (71-MER)
Authors:Akiyama, B.M, Laurence, H.M, Massey, A.R, Costantino, D.A, Xie, X, Yang, Y, Shi, P.-Y, Nix, J.C, Beckham, J.D, Kieft, J.S.
Deposit date:2016-10-21
Release date:2016-12-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease.
Science, 354, 2016
6D3P
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BU of 6d3p by Molmil
Crystal structure of an exoribonuclease-resistant RNA from Sweet clover necrotic mosaic virus (SCNMV)
Descriptor: IRIDIUM HEXAMMINE ION, RNA (45-MER)
Authors:Steckelberg, A.-L, Akiyama, B.M, Costantino, D.A, Sit, T.L, Nix, J.C, Kieft, J.S.
Deposit date:2018-04-16
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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