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4UMG
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BU of 4umg by Molmil
Crystal structure of the Lin-41 filamin domain
Descriptor: PROTEIN LIN-41
Authors:Tocchini, C, Keusch, J.J, Miller, S.B, Finger, S, Gut, H, Stadler, M, Ciosk, R.
Deposit date:2014-05-16
Release date:2014-10-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Trim-Nhl Protein Lin-41 Controls the Onset of Developmental Plasticity in Caenorhabditis Elegans.
Plos Genet., 10, 2014
6FQ3
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BU of 6fq3 by Molmil
Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with lin-29A 5'UTR 13mer RNA
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*GP*GP*AP*GP*UP*CP*CP*AP*AP*CP*UP*CP*C)-3')
Authors:Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R.
Deposit date:2018-02-13
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
3ZCO
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BU of 3zco by Molmil
Crystal structure of S. cerevisiae Sir3 C-terminal domain
Descriptor: REGULATORY PROTEIN SIR3
Authors:Oppikofer, M, Kueng, S, Keusch, J.J, Hassler, M, Ladurner, A.G, Gut, H, Gasser, S.M.
Deposit date:2012-11-21
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of Sir3 Via its C-Terminal Winged Helix Domain is Essential for Yeast Heterochromatin Formation.
Embo J., 32, 2013
6FPT
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BU of 6fpt by Molmil
Crystal structure of Danio rerio Lin41 filamin-NHL domains
Descriptor: E3 ubiquitin-protein ligase TRIM71
Authors:Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R.
Deposit date:2018-02-12
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
6FQL
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BU of 6fql by Molmil
Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with mab-10 3'UTR 13mer RNA
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*UP*GP*CP*AP*UP*UP*UP*AP*AP*UP*GP*CP*A)-3')
Authors:Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R.
Deposit date:2018-02-14
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
6I3H
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BU of 6i3h by Molmil
Crystal structure of influenza A virus M1 N-terminal domain (G18A mutation)
Descriptor: Matrix protein 1, PHOSPHATE ION
Authors:Miyake, Y, Keusch, J.J, Decamps, L, Ho-Xuan, H, Iketani, S, Gut, H, Kutay, U, Helenius, A, Yamauchi, Y.
Deposit date:2018-11-06
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Influenza virus uses transportin 1 for vRNP debundling during cell entry.
Nat Microbiol, 4, 2019
6QTM
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BU of 6qtm by Molmil
Crystal structure of the Sir4 H-BRCT domain in complex with Ty5 pS1095 peptide
Descriptor: Regulatory protein SIR4, Ribonuclease H, SULFATE ION
Authors:Gut, H, Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M.
Deposit date:2019-02-25
Release date:2019-09-18
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Embo J., 38, 2019
6QSZ
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BU of 6qsz by Molmil
Crystal structure of the Sir4 H-BRCT domain in complex with Esc1 pS1450 peptide
Descriptor: CHLORIDE ION, Regulatory protein SIR4, Silent chromatin protein ESC1
Authors:Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H.
Deposit date:2019-02-22
Release date:2019-09-18
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Embo J., 38, 2019
6RR0
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BU of 6rr0 by Molmil
Crystal structure of the Sir4 H-BRCT domain in complex with Ubp10 pT123 peptide
Descriptor: CHLORIDE ION, Regulatory protein SIR4, Ubiquitin carboxyl-terminal hydrolase 10
Authors:Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H.
Deposit date:2019-05-16
Release date:2019-09-18
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Embo J., 38, 2019
6RRV
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BU of 6rrv by Molmil
Crystal structure of the Sir4 H-BRCT domain
Descriptor: BROMIDE ION, CHLORIDE ION, Regulatory protein SIR4
Authors:Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H.
Deposit date:2019-05-20
Release date:2019-09-18
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.
Embo J., 38, 2019
5G0G
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BU of 5g0g by Molmil
Crystal structure of Danio rerio HDAC6 CD1 in complex with trichostatin A
Descriptor: CHLORIDE ION, HDAC6, SODIUM ION, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0I
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BU of 5g0i by Molmil
Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker cleaved) in complex with Nexturastat A
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, HDAC6, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0H
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BU of 5g0h by Molmil
Crystal structure of Danio rerio HDAC6 CD2 in complex with (S)- trichostatin A
Descriptor: 1,2-ETHANEDIOL, HDAC6, POTASSIUM ION, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0J
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BU of 5g0j by Molmil
Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker intact) in complex with Nexturastat A
Descriptor: CHLORIDE ION, HDAC6, NEXTURASTAT A, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0F
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BU of 5g0f by Molmil
Crystal structure of Danio rerio HDAC6 ZnF-UBP domain
Descriptor: GLYCINE, HDAC6, NICKEL (II) ION, ...
Authors:Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
4AE7
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BU of 4ae7 by Molmil
Crystal structure of human THEM5
Descriptor: THIOESTERASE SUPERFAMILY MEMBER 5
Authors:Zhuravleva, E, Gut, H, Hynx, D, Marcellin, D, Bleck, C.K.E, Genoud, C, Cron, P, Keusch, J.J, Dummler, B, Degli Esposti, M, Hemmings, B.A.
Deposit date:2012-01-09
Release date:2012-07-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
4AP6
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BU of 4ap6 by Molmil
Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ...
Authors:Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H.
Deposit date:2012-03-30
Release date:2012-08-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
4AE8
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BU of 4ae8 by Molmil
Crystal structure of human THEM4
Descriptor: THIOESTERASE SUPERFAMILY MEMBER 4
Authors:Zhuravleva, E, Gut, H, Hynx, D, Marcellin, D, Bleck, C.K.E, Genoud, C, Cron, P, Keusch, J.J, Dummler, B, Degli Esposti, M, Hemmings, B.A.
Deposit date:2012-01-09
Release date:2012-07-11
Method:X-RAY DIFFRACTION (1.594 Å)
Cite:Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
4AP5
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BU of 4ap5 by Molmil
Crystal structure of human POFUT2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ...
Authors:Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H.
Deposit date:2012-03-30
Release date:2012-08-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
5OMB
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BU of 5omb by Molmil
Crystal structure of K. lactis Ddc2 N-terminus in complex with S. cerevisiae Rfa1 N-OB domain
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA damage checkpoint protein LCD1, ...
Authors:Deshpande, I, Seeber, A, Shimada, K, Keusch, J.J, Gut, H, Gasser, S.M.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol. Cell, 68, 2017
5OMD
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BU of 5omd by Molmil
Crystal structure of S. cerevisiae Ddc2 N-terminal coiled-coil domain
Descriptor: DNA damage checkpoint protein LCD1
Authors:Deshpande, I, Seeber, A, Shimada, K, Keusch, J.J, Gut, H, Gasser, S.M.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol. Cell, 68, 2017
5OMC
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BU of 5omc by Molmil
Crystal structure of K. lactis Ddc2 N-terminus in complex with S. cerevisiae Rfa1 (K45E mutant) N-OB domain
Descriptor: CHLORIDE ION, DNA damage checkpoint protein LCD1, Replication factor A protein 1
Authors:Deshpande, I, Seeber, A, Shimada, K, Keusch, J.J, Gut, H, Gasser, S.M.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol. Cell, 68, 2017

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