Author results

3ZCO
  • Download 3zco
  • View 3zco
Molmil generated image of 3zco
CRYSTAL STRUCTURE OF S. CEREVISIAE SIR3 C-TERMINAL DOMAIN
Descriptor:REGULATORY PROTEIN SIR3
Authors:Oppikofer, M., Kueng, S., Keusch, J.J., Hassler, M., Ladurner, A.G., Gut, H., Gasser, S.M.
Deposit date:2012-11-21
Release date:2013-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of Sir3 Via its C-Terminal Winged Helix Domain is Essential for Yeast Heterochromatin Formation.
Embo J., 32, 2013
4AE7
  • Download 4ae7
  • View 4ae7
Molmil generated image of 4ae7
CRYSTAL STRUCTURE OF HUMAN THEM5
Descriptor:THIOESTERASE SUPERFAMILY MEMBER 5
Authors:Zhuravleva, E., Gut, H., Hynx, D., Marcellin, D., Bleck, C.K.E., Genoud, C., Cron, P., Keusch, J.J., Dummler, B., Degli Esposti, M., Hemmings, B.A.
Deposit date:2012-01-09
Release date:2012-07-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
4AE8
  • Download 4ae8
  • View 4ae8
Molmil generated image of 4ae8
CRYSTAL STRUCTURE OF HUMAN THEM4
Descriptor:THIOESTERASE SUPERFAMILY MEMBER 4
Authors:Zhuravleva, E., Gut, H., Hynx, D., Marcellin, D., Bleck, C.K.E., Genoud, C., Cron, P., Keusch, J.J., Dummler, B., Degli Esposti, M., Hemmings, B.A.
Deposit date:2012-01-09
Release date:2012-07-11
Method:X-RAY DIFFRACTION (1.594 Å)
Cite:Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
4AP5
  • Download 4ap5
  • View 4ap5
Molmil generated image of 4ap5
CRYSTAL STRUCTURE OF HUMAN POFUT2
Descriptor:GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Chen, C., Keusch, J.J., Klein, D., Hess, D., Hofsteenge, J., Gut, H.
Deposit date:2012-03-30
Release date:2012-08-08
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
4AP6
  • Download 4ap6
  • View 4ap6
Molmil generated image of 4ap6
CRYSTAL STRUCTURE OF HUMAN POFUT2 E54A MUTANT IN COMPLEX WITH GDP- FUCOSE
Descriptor:GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Chen, C., Keusch, J.J., Klein, D., Hess, D., Hofsteenge, J., Gut, H.
Deposit date:2012-03-30
Release date:2012-08-08
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
4UMG
  • Download 4umg
  • View 4umg
Molmil generated image of 4umg
CRYSTAL STRUCTURE OF THE LIN-41 FILAMIN DOMAIN
Descriptor:PROTEIN LIN-41
Authors:Tocchini, C., Keusch, J.J., Miller, S.B., Finger, S., Gut, H., Stadler, M., Ciosk, R.
Deposit date:2014-05-16
Release date:2014-10-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Trim-Nhl Protein Lin-41 Controls the Onset of Developmental Plasticity in Caenorhabditis Elegans.
Plos Genet., 10, 2014
5G0F
  • Download 5g0f
  • View 5g0f
Molmil generated image of 5g0f
CRYSTAL STRUCTURE OF DANIO RERIO HDAC6 ZNF-UBP DOMAIN
Descriptor:HDAC6, GLYCINE, ZINC ION, ...
Authors:Miyake, Y., Keusch, J.J., Wang, L., Saito, M., Hess, D., Wang, X., Melancon, B.J., Helquist, P., Gut, H., Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0G
  • Download 5g0g
  • View 5g0g
Molmil generated image of 5g0g
CRYSTAL STRUCTURE OF DANIO RERIO HDAC6 CD1 IN COMPLEX WITH TRICHOSTATIN A
Descriptor:HDAC6, ZINC ION, SODIUM ION, ...
Authors:Miyake, Y., Keusch, J.J., Wang, L., Saito, M., Hess, D., Wang, X., Melancon, B.J., Helquist, P., Gut, H., Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0H
  • Download 5g0h
  • View 5g0h
Molmil generated image of 5g0h
CRYSTAL STRUCTURE OF DANIO RERIO HDAC6 CD2 IN COMPLEX WITH (S)- TRICHOSTATIN A
Descriptor:HDAC6, S-Trichostatin A, POTASSIUM ION, ...
Authors:Miyake, Y., Keusch, J.J., Wang, L., Saito, M., Hess, D., Wang, X., Melancon, B.J., Helquist, P., Gut, H., Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0I
  • Download 5g0i
  • View 5g0i
Molmil generated image of 5g0i
CRYSTAL STRUCTURE OF DANIO RERIO HDAC6 CD1 AND CD2 (LINKER CLEAVED) IN COMPLEX WITH NEXTURASTAT A
Descriptor:HDAC6, ZINC ION, POTASSIUM ION, ...
Authors:Miyake, Y., Keusch, J.J., Wang, L., Saito, M., Hess, D., Wang, X., Melancon, B.J., Helquist, P., Gut, H., Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5G0J
  • Download 5g0j
  • View 5g0j
Molmil generated image of 5g0j
CRYSTAL STRUCTURE OF DANIO RERIO HDAC6 CD1 AND CD2 (LINKER INTACT) IN COMPLEX WITH NEXTURASTAT A
Descriptor:HDAC6, CHLORIDE ION, ZINC ION, ...
Authors:Miyake, Y., Keusch, J.J., Wang, L., Saito, M., Hess, D., Wang, X., Melancon, B.J., Helquist, P., Gut, H., Matthias, P.
Deposit date:2016-03-18
Release date:2016-07-27
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12, 2016
5OMB
  • Download 5omb
  • View 5omb
Molmil generated image of 5omb
CRYSTAL STRUCTURE OF K. LACTIS DDC2 N-TERMINUS IN COMPLEX WITH S. CEREVISIAE RFA1 N-OB DOMAIN
Descriptor:Replication factor A protein 1, DNA damage checkpoint protein LCD1, CHLORIDE ION, ...
Authors:Deshpande, I., Seeber, A., Shimada, K., Keusch, J.J., Gut, H., Gasser, S.M.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol. Cell, 68, 2017
5OMC
  • Download 5omc
  • View 5omc
Molmil generated image of 5omc
CRYSTAL STRUCTURE OF K. LACTIS DDC2 N-TERMINUS IN COMPLEX WITH S. CEREVISIAE RFA1 (K45E MUTANT) N-OB DOMAIN
Descriptor:Replication factor A protein 1, DNA damage checkpoint protein LCD1, CHLORIDE ION
Authors:Deshpande, I., Seeber, A., Shimada, K., Keusch, J.J., Gut, H., Gasser, S.M.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol. Cell, 68, 2017
5OMD
  • Download 5omd
  • View 5omd
Molmil generated image of 5omd
CRYSTAL STRUCTURE OF S. CEREVISIAE DDC2 N-TERMINAL COILED-COIL DOMAIN
Descriptor:DNA damage checkpoint protein LCD1
Authors:Deshpande, I., Seeber, A., Shimada, K., Keusch, J.J., Gut, H., Gasser, S.M.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol. Cell, 68, 2017
6FPT
  • Download 6fpt
  • View 6fpt
Molmil generated image of 6fpt
CRYSTAL STRUCTURE OF DANIO RERIO LIN41 FILAMIN-NHL DOMAINS
Descriptor:E3 ubiquitin-protein ligase TRIM71
Authors:Kumari, P., Aeschimann, F., Gaidatzis, D., Keusch, J.J., Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H., Grosshans, H., Ciosk, R.
Deposit date:2018-02-12
Release date:2018-05-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
6FQ3
  • Download 6fq3
  • View 6fq3
Molmil generated image of 6fq3
CRYSTAL STRUCTURE OF DANIO RERIO LIN41 FILAMIN-NHL DOMAINS IN COMPLEX WITH LIN-29A 5'UTR 13MER RNA
Descriptor:E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*GP*GP*AP*GP*UP*CP*CP*AP*AP*CP*UP*CP*C)-3'), CHLORIDE ION
Authors:Kumari, P., Aeschimann, F., Gaidatzis, D., Keusch, J.J., Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H., Grosshans, H., Ciosk, R.
Deposit date:2018-02-13
Release date:2018-05-09
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
6FQL
  • Download 6fql
  • View 6fql
Molmil generated image of 6fql
CRYSTAL STRUCTURE OF DANIO RERIO LIN41 FILAMIN-NHL DOMAINS IN COMPLEX WITH MAB-10 3'UTR 13MER RNA
Descriptor:E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*UP*GP*CP*AP*UP*UP*UP*AP*AP*UP*GP*CP*A)-3'), CHLORIDE ION
Authors:Kumari, P., Aeschimann, F., Gaidatzis, D., Keusch, J.J., Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H., Grosshans, H., Ciosk, R.
Deposit date:2018-02-14
Release date:2018-05-09
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018