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3L4G
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CRYSTAL STRUCTURE OF HOMO SAPIENS CYTOPLASMIC PHENYLALANYL-TRNA SYNTHETASE
Descriptor:Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain, PHENYLALANINE
Authors:Finarov, I., Moor, N., Kessler, N., Klipcan, L., Safro, M.G.
Deposit date:2009-12-20
Release date:2010-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of human cytosolic phenylalanyl-tRNA synthetase: evidence for kingdom-specific design of the active sites and tRNA binding patterns.
Structure, 18, 2010
3CMQ
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL PHENYLALANINE TRNA SYNTHETASE
Descriptor:Phenylalanyl-tRNA synthetase, mitochondrial, MAGNESIUM ION, ...
Authors:Klipcan, L., Levin, I.L., Kessler, N., Moor, N., Finarov, I., Safro, M.
Deposit date:2008-03-24
Release date:2008-07-01
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The tRNA-Induced Conformational Activation of Human Mitochondrial Phenylalanyl-tRNA Synthetase.
Structure, 16, 2008
3HFV
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL PHENYLALANYL-TRNA SYNTHETASE COMPLEXED WITH M-TYROSINE
Descriptor:Phenylalanyl-tRNA synthetase, mitochondrial, META-TYROSINE
Authors:Klipcan, L., Moor, N., Kessler, N., Safro, M.G.
Deposit date:2009-05-12
Release date:2009-07-21
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
3HFZ
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS PHENYLALANYL-TRNA SYNTHETASE COMPLEXED WITH M-TYROSINE
Descriptor:Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain, META-TYROSINE
Authors:Klipcan, L., Moor, N., Kessler, N., Safro, M.G.
Deposit date:2009-05-13
Release date:2009-07-21
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine
Proc.Natl.Acad.Sci.USA, 106, 2009
3TUP
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL PHERS COMPLEXED WITH TRNAPHE IN THE ACTIVE OPEN STATE
Descriptor:Phenylalanyl-tRNA synthetase, mitochondrial, Thermus thermophilus tRNAPhe
Authors:Safro, M., Klipcan, L., Moor, N., Finarov, I., Kessler, N., Sukhanova, M.
Deposit date:2011-09-17
Release date:2011-11-23
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal Structure of Human Mitochondrial PheRS Complexed with tRNA(Phe) in the Active "Open" State.
J.Mol.Biol., 415, 2012
1MD9
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CRYSTAL STRUCTURE OF DHBE IN COMPLEX WITH DHB AND AMP
Descriptor:2,3-dihydroxybenzoate-AMP ligase, ADENOSINE MONOPHOSPHATE, 2,3-DIHYDROXY-BENZOIC ACID
Authors:May, J.J., Kessler, N., Marahiel, M.A., Stubbs, M.T.
Deposit date:2002-08-07
Release date:2002-09-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
1MDB
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CRYSTAL STRUCTURE OF DHBE IN COMPLEX WITH DHB-ADENYLATE
Descriptor:2,3-dihydroxybenzoate-AMP ligase, SULFATE ION, ADENOSINE MONOPHOSPHATE, ...
Authors:May, J.J., Kessler, N., Marahiel, M.A., Stubbs, M.T.
Deposit date:2002-08-07
Release date:2002-09-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
1MDF
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CRYSTAL STRUCTURE OF DHBE IN ABSENCE OF SUBSTRATE
Descriptor:2,3-dihydroxybenzoate-AMP ligase, SULFATE ION
Authors:May, J.J., Kessler, N., Marahiel, M.A., Stubbs, M.T.
Deposit date:2002-08-07
Release date:2002-09-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 99, 2002
1NIZ
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NMR STRUCTURE OF A V3 (MN ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:Exterior membrane glycoprotein(GP120)
Authors:Sharon, M., Kessler, N., Levy, R., Zolla-Pazner, S., Gorlach, M., Anglister, J.
Deposit date:2002-12-30
Release date:2003-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
1NJ0
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NMR STRUCTURE OF A V3 (MN ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:Exterior membrane glycoprotein(GP120)
Authors:Sharon, M., Kessler, N., Levy, R., Zolla-Pazner, S., Gorlach, M., Anglister, J.
Deposit date:2002-12-30
Release date:2003-02-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
1U6U
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NMR STRUCTURE OF A V3 (IIIB ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:V3 peptide
Authors:Rosen, O., Chill, J., Sharon, M., Kessler, N., Mester, B., Zolla-Pazner, S., Anglister, J.
Deposit date:2004-08-02
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
1U6V
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NMR STRUCTURE OF A V3 (IIIB ISOLATE) PEPTIDE BOUND TO 447-52D, A HUMAN HIV-1 NEUTRALIZING ANTIBODY
Descriptor:V3 peptide
Authors:Rosen, O., Chill, J., Sharon, M., Kessler, N., Mester, B., Zolla-Pazner, S., Anglister, J.
Deposit date:2004-08-02
Release date:2005-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
2AC0
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STRUCTURAL BASIS OF DNA RECOGNITION BY P53 TETRAMERS (COMPLEX I)
Descriptor:5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
Authors:Kitayner, M., Rozenberg, H., Kessler, N., Rabinovich, D., Shakked, Z.
Deposit date:2005-07-18
Release date:2006-07-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2ADY
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STRUCTURAL BASIS OF DNA RECOGNITION BY P53 TETRAMERS (COMPLEX IV)
Descriptor:5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
Authors:Kitayner, M., Rozenberg, H., Kessler, N., Rabinovich, D., Shakked, Z.
Deposit date:2005-07-21
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2AHI
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STRUCTURAL BASIS OF DNA RECOGNITION BY P53 TETRAMERS (COMPLEX III)
Descriptor:5'-D(*CP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
Authors:Kitayner, M., Rozenberg, H., Kessler, N., Rabinovich, D., Shakked, Z.
Deposit date:2005-07-28
Release date:2006-07-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2ATA
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STRUCTURAL BASIS OF DNA RECOGNITION BY P53 TETRAMERS (COMPLEX II)
Descriptor:5'-D(*AP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*T)-3', Cellular tumor antigen p53, ZINC ION
Authors:Kitayner, M., Rozenberg, H., Kessler, N., Rabinovich, D., Shakked, Z.
Deposit date:2005-08-24
Release date:2006-07-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2HYM
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NMR BASED DOCKING MODEL OF THE COMPLEX BETWEEN THE HUMAN TYPE I INTERFERON RECEPTOR AND HUMAN INTERFERON ALPHA-2
Descriptor:Soluble IFN alpha/beta receptor, Interferon alpha-2
Authors:Quadt-Akabayov, S.R., Chill, J.H., Levy, R., Kessler, N., Anglister, J.
Deposit date:2006-08-07
Release date:2006-10-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex
Protein Sci., 15, 2006
2L87
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THE 27-RESIDUE N-TERMINUS CCR5-PEPTIDE IN A TERNARY COMPLEX WITH HIV-1 GP120 AND A CD4-MIMIC PEPTIDE
Descriptor:C-C chemokine receptor type 5
Authors:Schnur, E., Noah, E., Ayzenshtat, I., Sargsyan, H., Inui, T., Ding, F.X., Arshava, B., Sagi, Y., Kessler, N., Levy, R., Scherf, T., Naider, F., Anglister, J.
Deposit date:2011-01-06
Release date:2011-07-27
Method:SOLUTION NMR
Cite:The Conformation and Orientation of a 27-Residue CCR5 Peptide in a Ternary Complex with HIV-1 gp120 and a CD4-Mimic Peptide.
J.Mol.Biol., 410, 2011
3PCO
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CRYSTAL STRUCTURE OF E. COLI PHENYLALANINE-TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE AND AMP
Descriptor:Phenylalanyl-tRNA synthetase, alpha subunit, beta chain, ...
Authors:Mermershtain, I., Finarov, I., Klipcan, L., Kessler, N., Rozenberg, H., Safro, M.G.
Deposit date:2010-10-21
Release date:2011-03-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Idiosyncrasy and identity in the prokaryotic phe-system: crystal structure of E. coli phenylalanyl-tRNA synthetase complexed with phenylalanine and AMP.
Protein Sci., 20, 2011
2MZX
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CCR5-ECL2 HELICAL STRUCTURE, RESIDUES Q186-T195
Descriptor:C-C chemokine receptor type 5
Authors:Abayev, M., Anglister, J.
Deposit date:2015-02-26
Release date:2015-04-22
Last modified:2015-06-03
Method:SOLUTION NMR
Cite:An extended CCR5 ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions.
Febs J., 282, 2015
3D05
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HUMAN P53 CORE DOMAIN WITH HOT SPOT MUTATION R249S (II)
Descriptor:Cellular tumor antigen p53, ZINC ION
Authors:Suad, O., Rozenberg, H., Shimon, L.J.W., Frolow, F., Shakked, Z.
Deposit date:2008-05-01
Release date:2009-01-20
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D06
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HUMAN P53 CORE DOMAIN WITH HOT SPOT MUTATION R249S (I)
Descriptor:Cellular tumor antigen p53, ZINC ION
Authors:Rozenberg, H., Suad, O., Shimon, L.J.W., Frolow, F., Shakked, Z.
Deposit date:2008-05-01
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D07
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HUMAN P53 CORE DOMAIN WITH HOT SPOT MUTATION R249S (III)
Descriptor:Cellular tumor antigen p53, ZINC ION
Authors:Suad, O., Rozenberg, H., Shakked, Z.
Deposit date:2008-05-01
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D08
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HUMAN P53 CORE DOMAIN WITH HOT SPOT MUTATION R249S AND SECOND-SITE SUPPRESSOR MUTATION H168R
Descriptor:Cellular tumor antigen p53, ZINC ION
Authors:Suad, O., Rozenberg, H., Shimon, L.J.W., Frolow, F., Shakked, Z.
Deposit date:2008-05-01
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
3D09
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HUMAN P53 CORE DOMAIN WITH HOT SPOT MUTATION R249S AND SECOND-SITE SUPPRESSOR MUTATIONS H168R AND T123A
Descriptor:Cellular tumor antigen p53, ZINC ION
Authors:Rozenberg, H., Suad, O., Shakked, Z.
Deposit date:2008-05-01
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
J.Mol.Biol., 385, 2009
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