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Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e
Descriptor:	High affinity nerve growth factor receptor, N-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide
Authors:	Kensuke, A, Kazutaka, I.
Deposit date:	2019-01-11
Release date:	2019-07-17
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain. Bioorg.Med.Chem.Lett., 29, 2019