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1S1S
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BU of 1s1s by Molmil
Crystal Structure of ZipA in complex with indoloquinolizin 10b
Descriptor: Cell division protein zipA, N-{3-[(12bS)-7-oxo-1,3,4,6,7,12b-hexahydroindolo[2,3-a]quinolizin-12(2H)-yl]propyl}propane-2-sulfonamide
Authors:Jennings, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenny, C.H, Moghazeh, S.L, Petersen, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G.
Deposit date:2004-01-07
Release date:2005-01-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction
BIOORG.MED.CHEM.LETT., 14, 2004
3F5P
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BU of 3f5p by Molmil
Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor
Descriptor: 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile, Insulin-like growth factor 1 receptor
Authors:Xu, W, Miller, L.M, Mayer, S.C, Berger, D.M, Boschelli, D.H, Boschelli, F.
Deposit date:2008-11-04
Release date:2008-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment
Bioorg.Med.Chem.Lett., 19, 2009
1S1J
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BU of 1s1j by Molmil
Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1
Descriptor: (12bS)-1,2,3,4,12,12b-hexahydroindolo[2,3-a]quinolizin-7(6H)-one, Cell division protein zipA
Authors:Jenning, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenney, C.H, Moghazeh, S.L, Peterson, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G.
Deposit date:2004-01-06
Release date:2004-05-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction
Bioorg.Med.Chem.Lett., 14, 2004
2ZM3
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BU of 2zm3 by Molmil
Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor
Descriptor: (4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione, Insulin-like growth factor 1 receptor
Authors:Xu, W, Mayer, S.C, Boschelli, F, Johnson, M, Dwyer, B.
Deposit date:2008-04-10
Release date:2008-06-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment
Bioorg.Med.Chem.Lett., 18, 2008

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