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1LQ9
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR STRAIN A3(2)
Descriptor:ACTVA-ORF6 MONOOXYGENASE, TETRAETHYLENE GLYCOL
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-05-09
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
EMBO J., 22, 2003
1N5Q
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH DEHYDRATED SANCYCLINE
Descriptor:ActaVA-Orf6 monooxygenase, HEXAETHYLENE GLYCOL, 4-DIMETHYLAMINO-1,10,11,12-TETRAHYDROXY-3-OXO-3,4,4A,5-TETRAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5S
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH THE LIGAND ACETYL DITHRANOL
Descriptor:ActVA-Orf6 monooxygenase, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, (1,8-DIHYDROXY-9-OXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5V
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH THE LIGAND NANAOMYCIN D
Descriptor:ActVA-Orf6 monooxygenase, 7-HYDROXY-5-METHYL-3,3A,5,11B-TETRAHYDRO-1,4-DIOXA-CYCLOPENTA[A]ANTHRACENE-2,6,11-TRIONE
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
2JJN
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STRUCTURE OF CLOSED CYTOCHROME P450 ERYK
Descriptor:CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Savino, C., Sciara, G., Miele, A.E., Kendrew, S.G., Vallone, B.
Deposit date:2008-04-15
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
2JJO
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STRUCTURE OF CYTOCHROME P450 ERYK IN COMPLEX WITH ITS NATURAL SUBSTRATE ERD
Descriptor:CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, Erythromycin D
Authors:Savino, C., Sciara, G., Miele, A.E., Kendrew, S.G., Vallone, B.
Deposit date:2008-04-15
Release date:2009-07-14
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
1N5T
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH THE LIGAND OXIDIZED ACETYL DITHRANOL
Descriptor:ActVA-Orf6 monooxygenase, (1,8-DIHYDROXY-9,10-DIOXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID
Authors:Sciara, G., G Kendrew, S., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
2WIO
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STRUCTURE OF THE HISTIDINE TAGGED, OPEN CYTOCHROME P450 ERYK FROM S. ERYTHRAEA
Descriptor:ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Savino, C., Montemiglio, L.C., Sciara, G., Miele, A.E., Kedrew, S.G., Gianni, S., Vallone, B.
Deposit date:2009-05-14
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
2JJP
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STRUCTURE OF CYTOCHROME P450 ERYK IN COMPLEX WITH INHIBITOR KETOCONAZOLE (KC)
Descriptor:CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE, ...
Authors:Savino, C., Sciara, G., Miele, A.E., Kendrew, S.G., Vallone, B.
Deposit date:2008-04-15
Release date:2009-07-14
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Azole Drugs Trap Cytochrome P450 Eryk in Alternative Conformational States.
Biochemistry, 49, 2010