Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4UQI
DownloadVisualize
BU of 4uqi by Molmil
AP2 controls clathrin polymerization with a membrane-activated switch
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ...
Authors:Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J.
Deposit date:2014-06-23
Release date:2014-07-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch.
Science, 345, 2014
2JKT
DownloadVisualize
BU of 2jkt by Molmil
AP2 CLATHRIN ADAPTOR CORE with CD4 Dileucine peptide RM(phosphoS) EIKRLLSE Q to E mutant
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
Authors:Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2JKR
DownloadVisualize
BU of 2jkr by Molmil
AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
Authors:Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2XA7
DownloadVisualize
BU of 2xa7 by Molmil
AP2 clathrin adaptor core in active complex with cargo peptides
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ...
Authors:Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J.
Deposit date:2010-03-29
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
6YAF
DownloadVisualize
BU of 6yaf by Molmil
AP2 on a membrane containing tyrosine-based cargo peptide
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G.
Deposit date:2020-03-12
Release date:2020-07-29
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
6YAI
DownloadVisualize
BU of 6yai by Molmil
Clathrin with bound beta2 appendage of AP2
Descriptor: AP-2 complex subunit beta, Clathrin heavy chain, Clathrin light chain
Authors:Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G.
Deposit date:2020-03-12
Release date:2020-07-29
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
6YAE
DownloadVisualize
BU of 6yae by Molmil
AP2 core in physiological buffer
Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G.
Deposit date:2020-03-12
Release date:2020-07-29
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
6YAH
DownloadVisualize
BU of 6yah by Molmil
AP2 in clathrin coats assembled on a membrane containing dileucine- and tyrosine-based cargo peptides
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G.
Deposit date:2020-03-12
Release date:2020-07-29
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (10.2 Å)
Cite:Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
7OIT
DownloadVisualize
BU of 7oit by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form)
Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-12
Release date:2022-06-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHO
DownloadVisualize
BU of 7oho by Molmil
Crystal structure of AP2 FCHO2 chimera
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OG1
DownloadVisualize
BU of 7og1 by Molmil
AP2 clathrin adaptor core in complex with cargo peptide and FCHO2
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-05
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OIQ
DownloadVisualize
BU of 7oiq by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form)
Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-12
Release date:2022-06-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHI
DownloadVisualize
BU of 7ohi by Molmil
FCHO1-peptide-AP2 alpha ear complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AP-2 complex subunit alpha-2, F-BAR domain only protein 1, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OI5
DownloadVisualize
BU of 7oi5 by Molmil
Crystal structure of AP2 Mu2 - FCHO2 chimera (GST cleaved)
Descriptor: AP-2 complex subunit mu,F-BAR domain only protein 2, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OFP
DownloadVisualize
BU of 7ofp by Molmil
Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor
Descriptor: AP-2 complex subunit mu, CITRIC ACID, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-05
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHZ
DownloadVisualize
BU of 7ohz by Molmil
Crystal structure of AP2 Mu2 - FCHO2 chimera (His6-tagged)
Descriptor: AP-2 complex subunit mu,F-BAR domain only protein 2
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7Z5C
DownloadVisualize
BU of 7z5c by Molmil
Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R.
Deposit date:2022-03-09
Release date:2022-05-11
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
5M5R
DownloadVisualize
BU of 5m5r by Molmil
Clathrin heavy chain N-terminal domain bound to beta2 adaptin clathrin box motif
Descriptor: AP-2 complex subunit beta, Clathrin heavy chain 1
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M61
DownloadVisualize
BU of 5m61 by Molmil
Clathrin heavy chain N-terminal domain bound to an extended amphiphysin clathrin-box motif
Descriptor: Amphiphysin, Clathrin heavy chain 1, GLYCEROL
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-23
Release date:2016-11-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5T
DownloadVisualize
BU of 5m5t by Molmil
Clathrin heavy chain N-terminal domain bound to a non-natural clathrin-box motif peptide (Amph4T1)
Descriptor: Amphiphysin, Clathrin heavy chain 1, GLYCEROL
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5V
DownloadVisualize
BU of 5m5v by Molmil
Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large antigen (clade 2)
Descriptor: Clathrin heavy chain 1, GLYCEROL, Large delta antigen
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5U
DownloadVisualize
BU of 5m5u by Molmil
Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large antigen (clade 1)
Descriptor: Clathrin heavy chain 1, GLYCEROL, Large delta antigen
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
5M5S
DownloadVisualize
BU of 5m5s by Molmil
Clathrin heavy chain N-terminal domain bound to amphiphysin clathrin-box motif
Descriptor: Amphiphysin, Clathrin heavy chain 1, GLYCEROL
Authors:Muenzner, J, Graham, S.C.
Deposit date:2016-10-22
Release date:2016-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Cellular and viral peptides bind multiple sites on the N-terminal domain of clathrin.
Traffic, 18, 2017
6QH7
DownloadVisualize
BU of 6qh7 by Molmil
AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6RH6
DownloadVisualize
BU of 6rh6 by Molmil
Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of NECAP1 PHear domain with phosphorylated AP2 mu2 148-163
Descriptor: AP-2 complex subunit mu, Adaptin ear-binding coat-associated protein 1
Authors:Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019

 

12>

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon