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1QSC
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BU of 1qsc by Molmil
CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF2 IN A COMPLEX WITH A PEPTIDE FROM THE CD40 RECEPTOR
Descriptor: CD40 RECEPTOR, TNF RECEPTOR ASSOCIATED FACTOR 2
Authors:McWhirter, S.M, Pullen, S.S, Holton, J.M, Crute, J.J, Kehry, M.R, Alber, T.
Deposit date:1999-06-20
Release date:1999-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic analysis of CD40 recognition and signaling by human TRAF2.
Proc.Natl.Acad.Sci.USA, 96, 1999
3NMQ
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BU of 3nmq by Molmil
Hsp90b N-terminal domain in complex with EC44, a pyrrolo-pyrimidine methoxypyridine inhibitor
Descriptor: 5-{2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-methylpent-4-yn-2 -ol, Heat shock protein HSP 90-beta
Authors:Arndt, J.W, Yun, T.J, Harning, E.K, Giza, K, Rabah, D, Li, P, Luchetti, D, Shi, J, Manning, A, Kehry, M.R.
Deposit date:2010-06-22
Release date:2010-12-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity.
J.Immunol., 186, 2011
3QDD
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BU of 3qdd by Molmil
HSP90A N-terminal domain in complex with BIIB021
Descriptor: 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, Heat shock protein HSP 90-alpha
Authors:Arndt, J.W, Biamonte, M.A.
Deposit date:2011-01-18
Release date:2012-07-18
Last modified:2022-10-05
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:EC144 Is a Potent Inhibitor of the Heat Shock Protein 90.
J.Med.Chem., 55, 2012

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