Author results

2VPJ
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CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KLHL12
分子名称:KELCH-LIKE PROTEIN 12, ACETATE ION
著者Keates, T., Pike, A.C.W., Bullock, A.N., Salah, E., Filippakopoulos, P., Roos, A.K., von Delft, F., Savitsky, P., Weigelt, J., Edwards, A., Arrowsmith, C.H., Bountra, C., Knapp, S.
登録日2008-02-29
公開日2008-03-18
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
3PRY
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CRYSTAL STRUCTURE OF THE MIDDLE DOMAIN OF HUMAN HSP90-BETA REFINED AT 2.3 A RESOLUTION
分子名称:Heat shock protein HSP 90-beta, SULFATE ION, GLYCEROL, ...
著者Chaikuad, A., Pilka, E., Sharpe, T.D., Cooper, C.D.O., Phillips, C., Berridge, G., Ayinampudi, V., Fedorov, O., Keates, T., Thangaratnarajah, C., Zimmermann, T., Vollmar, M., Yue, W.W., Che, K.H., Krojer, T., Muniz, J.R.C., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bullock, A., Structural Genomics Consortium (SGC)
登録日2010-11-30
公開日2010-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structure of the middle domain of human HSP90-beta refined at 2.3 A resolution
To be Published
3I3N
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CRYSTAL STRUCTURE OF THE BTB-BACK DOMAINS OF HUMAN KLHL11
分子名称:Kelch-like protein 11, THIOCYANATE ION, CHLORIDE ION
著者Murray, J.W., Cooper, C.D.O., Krojer, T., Mahajan, P., Salah, E., Keates, T., Savitsky, P., Pike, A.C.W., Roos, A., Muniz, J., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Bullock, A., Structural Genomics Consortium (SGC)
登録日2009-06-30
公開日2009-08-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the BTB-BACK domains of human KLHL11
To be Published
3K2J
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CRYSTAL STRUCTURE OF THE 3RD BROMODOMAIN OF HUMAN POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)
分子名称:Protein polybromo-1, CHLORIDE ION, SULFATE ION
著者Filippakopoulos, P., Picaud, S., Keates, T., Chaikuad, A., Pike, A.C.W., Krojer, T., Sethi, R., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-09-30
公開日2009-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the 3rd Bromodomain of Human Poly-bromodomain containing protein 1 (PB1)
To be Published
3LXJ
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN AAA DOMAIN CONTAINING 2B (ATAD2B)
分子名称:ATPase family AAA domain-containing protein 2B, ISOPROPYL ALCOHOL
著者Filippakopoulos, P., Keates, T., Picaud, S., Fedorov, O., Krojer, T., Vollmar, M., Muniz, J., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-02-25
公開日2010-03-09
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3MQM
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN ASH1L
分子名称:Probable histone-lysine N-methyltransferase ASH1L
著者Filippakopoulos, P., Picaud, S., Keates, T., Felletar, I., Vollmar, M., Chaikuad, A., Krojer, T., Canning, P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-04-28
公開日2010-05-19
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3MTL
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CRYSTAL STRUCTURE OF THE PCTAIRE1 KINASE IN COMPLEX WITH INDIRUBIN E804
分子名称:Cell division protein kinase 16, (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}
著者Krojer, T., Sharpe, T.D., Roos, A., Savitsky, P., Amos, A., Ayinampudi, V., Berridge, G., Fedorov, O., Keates, T., Phillips, C., Burgess-Brown, N., Zhang, Y., Pike, A.C.W., Muniz, J., Vollmar, M., Thangaratnarajah, C., Rellos, P., Ugochukwu, E., Filippakopoulos, P., Yue, W., Das, S., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., Knapp, S., Bullock, A., Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804
to be published
3NR9
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STRUCTURE OF HUMAN CDC2-LIKE KINASE 2 (CLK2)
分子名称:Dual specificity protein kinase CLK2, (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one
著者Chaikuad, A., Savitsky, P., Krojer, T., Muniz, J.R.C., Filippakopoulos, P., Rellos, P., Keates, T., Fedorov, O., Pike, A.C.W., Eswaran, J., Berridge, G., Phillips, C., Zhang, Y., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-06-30
公開日2010-08-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structure of human CDC2-like kinase 2 (CLK2)
To be Published
3Q2E
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CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF HUMAN BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 ISOFORM A (WDR9)
分子名称:Bromodomain and WD repeat-containing protein 1, ACETATE ION
著者Filippakopoulos, P., Felletar, I., Picaud, S., Keates, T., Krojer, T., Muniz, J., Gileadi, O., Von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-12-20
公開日2011-02-16
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3RCW
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN BRD1
分子名称:Bromodomain-containing protein 1, 1-methylpyrrolidin-2-one, ACETATE ION, ...
著者Filippakopoulos, P., Keates, T., Picaud, S., Felletar, I., Pike, A.C.W., Krojer, T., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2011-03-31
公開日2011-06-01
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3TLP
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CRYSTAL STRUCTURE OF THE FOURTH BROMODOMAIN OF HUMAN POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)
分子名称:Protein polybromo-1, NICKEL (II) ION
著者Filippakopoulos, P., Felletar, I., Picaud, S., Keates, T., Muniz, J., Krojer, T., Allerston, C.K., Latwiel, S., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2011-08-30
公開日2011-09-28
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2OO1
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CRYSTAL STRUCTURE OF THE BROMO DOMAIN 2 OF HUMAN BROMODOMAIN CONTAINING PROTEIN 3 (BRD3)
分子名称:Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL, ...
著者Filippakopoulos, P., Bullock, A., Papagrigoriou, E., Keates, T., Cooper, C., Smee, C., Ugochukwu, E., Debreczeni, J., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
登録日2007-01-25
公開日2007-02-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2OSS
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CRYSTAL STRUCTURE OF THE BROMO DOMAIN 1 IN HUMAN BROMODOMAIN CONTAINING PROTEIN 4 (BRD4)
分子名称:Bromodomain-containing protein 4, 1,2-ETHANEDIOL
著者Filippakopoulos, P., Keates, T., Savitsky, P., Burgess, N., Pike, A.C.W., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
登録日2007-02-06
公開日2007-02-20
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2OUO
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CRYSTAL STRUCTURE OF THE BROMO DOMAIN 2 IN HUMAN BROMODOMAIN CONTAINING PROTEIN 4 (BRD4)
分子名称:Bromodomain-containing protein 4, 1,2-ETHANEDIOL
著者Filippakopoulos, P., Keates, T., Savitsky, P., Burgess, N., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
登録日2007-02-12
公開日2007-02-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2RFJ
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CRYSTAL STRUCTURE OF THE BROMO DOMAIN 1 IN HUMAN BROMODOMAIN CONTAINING PROTEIN, TESTIS SPECIFIC (BRDT)
分子名称:Bromodomain testis-specific protein
著者Filippakopoulos, P., Salah, E., Savitsky, P., Keates, T., Parizotto, E., Elkins, J., Pike, A.C.W., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
登録日2007-09-30
公開日2007-10-23
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3DAI
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF THE HUMAN ATAD2
分子名称:ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION
著者Filippakopoulos, P., Keates, T., Picaud, S., Fedorov, O., Roos, A.K., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2008-05-29
公開日2008-09-09
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3GG3
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN PCAF
分子名称:Histone acetyltransferase PCAF, CHLORIDE ION
著者Filippakopoulos, P., Keates, T., Picaud, S., Rehana, K., Fedorov, O., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-02-27
公開日2009-03-17
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3HME
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CRYSTAL STRUCTURE OF HUMAN BROMODOMAIN CONTAINING 9 ISOFORM 1 (BRD9)
分子名称:Bromodomain-containing protein 9
著者Filippakopoulos, P., Eswaran, J., Keates, T., Picaud, S., Roos, A., Chaikuad, A., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-05-29
公開日2009-06-23
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3HMF
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CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF HUMAN POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)
分子名称:Protein polybromo-1, ZINC ION, 1,2-ETHANEDIOL, ...
著者Filippakopoulos, P., Picaud, S., Keates, T., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-05-29
公開日2009-06-23
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3HMH
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CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF HUMAN TBP-ASSOCIATED FACTOR RNA POLYMERASE 1-LIKE (TAF1L)
分子名称:Transcription initiation factor TFIID 210 kDa subunit
著者Filippakopoulos, P., Picaud, S., Keates, T., Zhang, Y., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-05-29
公開日2009-06-23
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3IU5
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)
分子名称:Protein polybromo-1
著者Filippakopoulos, P., Picaud, S., Keates, T., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-08-30
公開日2009-09-22
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3IU6
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CRYSTAL STRUCTURE OF THE SIXTH BROMODOMAIN OF HUMAN POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)
分子名称:Protein polybromo-1, 1,2-ETHANEDIOL, ZINC ION
著者Filippakopoulos, P., Keates, T., Picaud, S., Pike, A.C.W., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-08-30
公開日2009-09-22
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3MB3
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CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF PLECKSTRIN HOMOLOGY DOMAIN INTERACTING PROTEIN (PHIP)
分子名称:PH-interacting protein, 1-methylpyrrolidin-2-one
著者Filippakopoulos, P., Picaud, S., Keates, T., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-03-25
公開日2010-04-14
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3MB4
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CRYSTAL STRUCTURE OF THE FIFTH BROMODOMAIN OF HUMAN POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1) WITH NMP
分子名称:Protein polybromo-1, 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, ...
著者Filippakopoulos, P., Picaud, S., Keates, T., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-03-25
公開日2010-04-14
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3NXB
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CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN CECR2
分子名称:Cat eye syndrome critical region protein 2, 1,2-ETHANEDIOL
著者Filippakopoulos, P., Picaud, S., Keates, T., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-07-13
公開日2010-08-18
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012