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1EQB
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X-RAY CRYSTAL STRUCTURE AT 2.7 ANGSTROMS RESOLUTION OF TERNARY COMPLEX BETWEEN THE Y65F MUTANT OF E-COLI SERINE HYDROXYMETHYLTRANSFERASE, GLYCINE AND 5-FORMYL TETRAHYDROFOLATE
Descriptor:SERINE HYDROXYMETHYLTRANSFERASE, GLYCINE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Contestabile, R., Angelaccio, S., Bossa, F., Wright, H.T., Scarsdale, N., Kazanina, G., Schirch, V.
Deposit date:2000-04-03
Release date:2000-04-19
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Role of tyrosine 65 in the mechanism of serine hydroxymethyltransferase.
Biochemistry, 39, 2000
1CJ0
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CRYSTAL STRUCTURE OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE AT 2.8 ANGSTROM RESOLUTION
Descriptor:PROTEIN (SERINE HYDROXYMETHYLTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE
Authors:Scarsdale, J.N., Kazanina, G., Radaev, S., Schirch, V., Wright, H.T.
Deposit date:1999-04-20
Release date:1999-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 A resolution: mechanistic implications.
Biochemistry, 38, 1999
1DFO
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CRYSTAL STRUCTURE AT 2.4 ANGSTROM RESOLUTION OF E. COLI SERINE HYDROXYMETHYLTRANSFERASE IN COMPLEX WITH GLYCINE AND 5-FORMYL TETRAHYDROFOLATE
Descriptor:SERINE HYDROXYMETHYLTRANSFERASE, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
Authors:Scarsdale, J.N., Radaev, S., Kazanina, G., Schirch, V., Wright, H.T.
Deposit date:1999-11-20
Release date:1999-12-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate.
J.Mol.Biol., 296, 2000
1HZP
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CRYSTAL STRUCTURE OF THE MYOBACTERIUM TUBERCULOSIS BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III, LAURIC ACID, GLYCEROL
Authors:Scarsdale, J.N., Kazanina, G., He, X., Reynolds, K.A., Wright, H.T., TB Structural Genomics Consortium (TBSGC)
Deposit date:2001-01-25
Release date:2001-06-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III
J.Biol.Chem., 276, 2001
1LS3
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE AND TRIGLU-5-FORMYL-TETRAHYDROFOLATE
Descriptor:Serine Hydroxymethyltransferase, PYRIDOXAL-5'-PHOSPHATE, GLYCINE, ...
Authors:Fu, T.F., Scarsdale, J.N., Kazanina, G., Schirch, V., Wright, H.T.
Deposit date:2002-05-16
Release date:2003-02-04
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Location of the Pteroylpolyglutamate Binding Site on Rabbit Cytosolic Serine Hydroxymethyltransferase
J.Biol.Chem., 278, 2003
1U6E
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1.85 ANGSTROM CRYSTAL STRUCTURE OF THE C112A MUTANT OF MYCOBACTERIUM TUBERCULOSIS BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (FABH)
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase III, CHLORIDE ION
Authors:Mussayev, F., Sachedeva, S., Scarsdale, J.N., Reynolds, K.A., Wright, H.T.
Deposit date:2004-07-29
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A.
J.Mol.Biol., 346, 2005
1U6S
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MYCOBACTERIUM TUBERCULOSIS BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III AND LAUROYL COENZYME A
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase III, DODECYL-COA
Authors:Musayev, F., Sachdeva, S., Scarsdale, J.N., Reynolds, K.A., Wright, H.T.
Deposit date:2004-07-30
Release date:2005-03-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A.
J.Mol.Biol., 346, 2005
2QNX
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE MYCOBACTERIUM BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (FABH) AND 11-[(DECYLOXYCARBONYL)DITHIO]-UNDECANOIC ACID
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 3, O-DECYL HYDROGEN THIOCARBONATE, 11-MERCAPTOUNDECANOIC ACID
Authors:Sachdeva, S., Musayev, F., Alhamadsheh, M., Scarsdale, J.N., Wright, H.T., Reynolds, K.A.
Deposit date:2007-07-19
Release date:2008-05-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH
Chem.Biol., 15, 2008
2QNY
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE A246F MUTANT OF MYCOBACTERIUM BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (FABH) AND SS-(2-HYDROXYETHYL) O-DECYL ESTER CARBONO(DITHIOPEROXOIC) ACID
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 3, DECYL FORMATE, BETA-MERCAPTOETHANOL
Authors:Sachdeva, S., Musayev, F., Alhamadsheh, M., Scarsdale, J.N., Wright, H.T., Reynolds, K.A.
Deposit date:2007-07-19
Release date:2008-05-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH
Chem.Biol., 15, 2008
2QNZ
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE MYCOBACTERIUM BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (FABH) AND SS-(2-HYDROXYETHYL)-O-DECYL ESTER CARBONO(DITHIOPEROXOIC) ACID
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 3, DECYL FORMATE, BETA-MERCAPTOETHANOL
Authors:Sachdeva, S., Musayev, F., Alhamadsheh, M., Scarsdale, J.N., Wright, H.T., Reynolds, K.A.
Deposit date:2007-07-19
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH
Chem.Biol., 15, 2008
2QO0
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE A246F MUTANT OF MYCOBACTERIUM BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (FABH) AND 11-(DECYLDITHIOCARBONYLOXY)-UNDECANOIC ACID
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 3, DECANE-1-THIOL
Authors:Sachdeva, S., Musayev, F., Alhamadsheh, M., Scarsdale, J.N., Wright, H.T., Reynolds, K.A.
Deposit date:2007-07-19
Release date:2008-05-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH
Chem.Biol., 15, 2008
2QO1
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2.6 ANGSTROM CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN 11-(DECYLDITHIOCARBONYLOXY)-UNDECANOIC ACID AND MYCOBACTERIUM TUBERCULOSIS FABH.
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 3, 11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC ACID, DECANE-1-THIOL
Authors:Sachdeva, S., Musayev, F., Alhamadsheh, M., Scarsdale, J.N., Wright, H.T., Reynolds, K.A.
Deposit date:2007-07-19
Release date:2008-05-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH
Chem.Biol., 15, 2008
2QX1
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN MYCOBACTERIUM TUBERCULOSIS BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (FABH) AND DECYL-COA DISULFIDE
Descriptor:Beta-ketoacyl-ACP synthase III, COENZYME A, DECANE-1-THIOL
Authors:Sachdeva, S., Musayev, F., Alhamadsheh, M., Scarsdale, J.N., Wright, H.T., Reynolds, K.A.
Deposit date:2007-08-10
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates
Bioorg.Chem., 36, 2008