Author results

3N6W
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CRYSTAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE
Descriptor:Gamma-butyrobetaine dioxygenase, ZINC ION, SULFATE ION
Authors:Rumnieks, J., Zeltins, A., Leonchiks, A., Kazaks, A., Kotelovica, S., Tars, K.
Deposit date:2010-05-26
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human gamma-butyrobetaine hydroxylase.
Biochem.Biophys.Res.Commun., 398, 2010
2W4Y
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CAULOBACTER BACTERIOPHAGE 5 - VIRUS-LIKE PARTICLE
Descriptor:CAULOBACTER 5 VIRUS-LIKE PARTICLE, CALCIUM ION, ADENOSINE MONOPHOSPHATE
Authors:Plevka, P., Kazaks, A., Dishlers, A., Liljas, L., Tars, K.
Deposit date:2008-12-02
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of Bacteriophage Phicb5 Reveals a Role of the RNA Genome and Metal Ions in Particle Stability and Assembly.
J.Mol.Biol., 391, 2009
2W4Z
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CAULOBACTER BACTERIOPHAGE 5
Descriptor:CAULOBACTER BACTERIOPHAGE 5, CALCIUM ION, ADENOSINE MONOPHOSPHATE
Authors:Plevka, P., Kazaks, A., Dishlers, A., Liljas, L., Tars, K.
Deposit date:2008-12-02
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Structure of Bacteriophage Phicb5 Reveals a Role of the RNA Genome and Metal Ions in Particle Stability and Assembly.
J.Mol.Biol., 391, 2009
4BCW
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CARBONIC ANHYDRASE IX MIMIC IN COMPLEX WITH (E)-2-(5-BROMO-2- HYDROXYPHENYL)ETHENESULFONIC ACID
Descriptor:CARBONIC ANHYDRASE 2, ZINC ION, (E)-2-(5-BROMO-2-HYDROXYPHENYL)ETHENESULFONIC ACID
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2012-10-03
Release date:2013-02-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Sulfocoumarins (1,2-Benzoxathiine-2,2-Dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases.
J.Med.Chem., 56, 2013
6GOL
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THREE DIMENSIONAL STRUCTURE OF A NOVEL INFLUENZA HEMAGGLUTININ TRI-STALK PROTEIN
Descriptor:Hemagglutinin tri-stalk
Authors:Kirsteina, A., Kazaks, A., Tars, K.
Deposit date:2018-06-01
Release date:2018-10-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and applications of novel influenza HA tri-stalk protein for evaluation of HA stem-specific immunity.
PLoS ONE, 13, 2018
2YN7
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CRYSTAL STRUCTURE OF AN OUTER SURFACE PROTEIN BBA66 FROM BORRELIA BURGDORFERI
Descriptor:OUTER SURFACE PROTEIN
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Baumanis, V., Tars, K.
Deposit date:2012-10-12
Release date:2013-10-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the Infectious Phenotype-Associated Outer Surface Protein Bba66 from the Lyme Disease Agent Borrelia Burgdorferi.
Ticks Tick Borne Dis., 5, 2014
4ALY
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BORRELIA BURGDORFERI OUTER SURFACE LIPOPROTEIN BBA64
Descriptor:P35 ANTIGEN, SULFATE ION
Authors:Brangulis, K., Tars, K., Petrovskis, I., Kazaks, A., Ranka, R., Baumanis, V.
Deposit date:2012-03-06
Release date:2013-04-17
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of an Outer Surface Lipoprotein Bba64 from the Lyme Disease Agent Borrelia Burgdorferi which is Critical to Ensure Infection After a Tick Bite
Acta Crystallogr.,Sect.D, 69, 2013
4AXZ
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BORRELIA BURGDORFERI OUTER SURFACE LIPOPROTEIN BBA73
Descriptor:PUTATIVE ANTIGEN P35
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Baumanis, V., Tars, K.
Deposit date:2012-06-15
Release date:2013-05-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Characterization of the Borrelia Burgdorferi Outer Surface Protein Bba73 Implicates Dimerization as a Functional Mechanism.
Biochem.Biophys.Res.Commun., 434, 2013
4B2F
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N-TERMINAL DELETION MUTANT OF AN OUTER SURFACE PROTEIN BBA73 FROM BORRELIA BURGDORFERI
Descriptor:PUTATIVE ANTIGEN P35
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2012-07-15
Release date:2013-05-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural Characterization of the Borrelia Burgdorferi Outer Surface Protein Bba73 Implicates Dimerization as a Functional Mechanism.
Biochem.Biophys.Res.Commun., 434, 2013
4BG1
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 1-(3-CARBOXYPROPYL)-1-METHYLPYRROLIDIN-1-IUM CHLORIDE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 1-(3-carboxypropyl)-1-methylpyrrolidin-1-ium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-03-22
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BG5
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LYME DISEASE ASSOCIATED OUTER SURFACE PROTEIN BBA65 FROM BORRELIA BURGDORFERI
Descriptor:BBA65
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2013-03-22
Release date:2014-04-09
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Outer Surface Protein Bba65 from Borrelia Burgdorferi
To be Published
4BGK
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH (3-(TRIMETHYLAMMONIO)PROPYL)PHOSPHINATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, trimethyl(3-oxidanylphosphonoylpropyl)azanium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-03-27
Release date:2014-03-12
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BGM
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 3-CARBOXY-N-(2-FLUOROETHYL)-N,N-DIMETHYLPROPAN-1- AMINIUM CHLORIDE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 3-Carboxy-N-(2-fluoroethyl)-N,N-dimethylpropan-1-aminium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-03-27
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BHF
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 4-(TRIMETHYLAMMONIO)PENTANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 4-(Trimethylammonio)pentanoic acid, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-04-02
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BHG
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 3-(1-ETHYL-1,1-DIMETHYLHYDRAZIN-1-IUM-2-YL)PROPANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 3-(1-Ethyl-1,1-dimethylhydrazin-1-ium-2-yl)propanoic acid, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-04-02
Release date:2014-04-16
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1-Ethyl-1,1-Dimethylhydrazin-1-Ium-2-Yl)Propanoate
To be Published
4BHI
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 3-(1,1,1,2-TETRAMETHYLHYDRAZIN-1-IUM-2-YL)PROPANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 3-(1,1,1,2-TETRAMETHYLHYDRAZIN-1-IUM-2-YL)PROPANOATE, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-04-03
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BOD
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COMPLEMENT REGULATOR ACQUIRING OUTER SURFACE PROTEIN BBCRASP-4 OR ERPC FROM BORRELIA BURGDORFERI
Descriptor:ERPC
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Baumanis, V., Tars, K.
Deposit date:2013-05-18
Release date:2014-05-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Crystal Structures of the Erp Protein Family Members Erpp and Erpc from Borrelia Burgdorferi Reveal the Reason for Different Affinities for Complement Regulator Factor H.
Biochim.Biophys.Acta, 1854, 2015
4BXM
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COMPLEMENT REGULATOR ACQUIRING OUTER SURFACE PROTEIN BBCRASP-4 OR ERPC FROM BORRELIA BURGDORFERI
Descriptor:ERPC
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Tars, K.
Deposit date:2013-07-13
Release date:2014-07-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structures of the Erp Protein Family Members Erpp and Erpc from Borrelia Burgdorferi Reveal the Reason for Different Affinities for Complement Regulator Factor H.
Biochim.Biophys.Acta, 1854, 2015
4C5W
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 4-(ETHYLDIMETHYLAMMONIO)BUTANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, ethyl-dimethyl-(4-oxidanyl-4-oxidanylidene-butyl)azanium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-09-16
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4CBE
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CRYSTAL STRUCTURE OF COMPLEMENT FACTORS H AND FHL-1 BINDING PROTEIN BBH06 OR CRASP-2 FROM BORRELIA BURGDORFERI (NATIVE)
Descriptor:COMPLEMENT REGULATOR-ACQUIRING SURFACE PROTEIN 2 (CRASP-2)
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Tars, K.
Deposit date:2013-10-13
Release date:2014-04-16
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural Characterization of Cspz, a Complement Regulator Factor H and Fhl-1 Binding Protein from Borrelia Burgdorferi.
FEBS J., 281, 2014
4D53
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OUTER SURFACE PROTEIN BB0689 FROM BORRELIA BURGDORFERI
Descriptor:BB0689
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2014-11-02
Release date:2015-10-14
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Functional Analysis of Bb0689 from Borrelia Burgdorferi, a Member of the Bacterial CAP Superfamily.
J.Struct.Biol., 192, 2015
5A2U
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CRYSTAL STRUCTURE OF BBA68 OR BBCRASP-1 FROM BORRELIA BURGDORFERI STRAIN B31
Descriptor:COMPLEMENT REGULATOR ACQUIRING PROTEIN 1
Authors:Brangulis, K., Bertulis, E., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2015-05-25
Release date:2015-06-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of Bba68 or Bbcrasp-1 from Borrelia Burgdorferi Strain B31
To be Published
5ODJ
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SINGLE-STRANDED DNA-BINDING PROTEIN FROM BACTERIOPHAGE ENC34
Descriptor:Single-stranded DNA-binding protein, MAGNESIUM ION, CHLORIDE ION
Authors:Cernooka, E., Rumnieks, J., Kazaks, A., Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
5ODK
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SINGLE-STRANDED DNA-BINDING PROTEIN FROM BACTERIOPHAGE ENC34, C-TERMINAL TRUNCATION
Descriptor:single-stranded DNA-binding protein, PHOSPHATE ION, GLYCEROL
Authors:Cernooka, E., Rumnieks, J., Kazaks, A., Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
5ODL
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SINGLE-STRANDED DNA-BINDING PROTEIN FROM BACTERIOPHAGE ENC34 IN COMPLEX WITH SSDNA
Descriptor:single-stranded DNA-binding protein, oligo(T), GLYCEROL, ...
Authors:Cernooka, E., Rumnieks, J., Kazaks, A., Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
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