Author results

3N6W
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CRYSTAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE
Descriptor:Gamma-butyrobetaine dioxygenase, ZINC ION, SULFATE ION
Authors:Rumnieks, J., Zeltins, A., Leonchiks, A., Kazaks, A., Kotelovica, S., Tars, K.
Deposit date:2010-05-26
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human gamma-butyrobetaine hydroxylase.
Biochem.Biophys.Res.Commun., 398, 2010
2W4Y
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CAULOBACTER BACTERIOPHAGE 5 - VIRUS-LIKE PARTICLE
Descriptor:CAULOBACTER 5 VIRUS-LIKE PARTICLE, CALCIUM ION, ADENOSINE MONOPHOSPHATE
Authors:Plevka, P., Kazaks, A., Dishlers, A., Liljas, L., Tars, K.
Deposit date:2008-12-02
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of Bacteriophage Phicb5 Reveals a Role of the RNA Genome and Metal Ions in Particle Stability and Assembly.
J.Mol.Biol., 391, 2009
2W4Z
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CAULOBACTER BACTERIOPHAGE 5
Descriptor:CAULOBACTER BACTERIOPHAGE 5, CALCIUM ION, ADENOSINE MONOPHOSPHATE
Authors:Plevka, P., Kazaks, A., Dishlers, A., Liljas, L., Tars, K.
Deposit date:2008-12-02
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Structure of Bacteriophage Phicb5 Reveals a Role of the RNA Genome and Metal Ions in Particle Stability and Assembly.
J.Mol.Biol., 391, 2009
4BCW
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CARBONIC ANHYDRASE IX MIMIC IN COMPLEX WITH (E)-2-(5-BROMO-2- HYDROXYPHENYL)ETHENESULFONIC ACID
Descriptor:CARBONIC ANHYDRASE 2, ZINC ION, (E)-2-(5-BROMO-2-HYDROXYPHENYL)ETHENESULFONIC ACID
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2012-10-03
Release date:2013-02-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Sulfocoumarins (1,2-Benzoxathiine-2,2-Dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases.
J.Med.Chem., 56, 2013
6GOL
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THREE DIMENSIONAL STRUCTURE OF A NOVEL INFLUENZA HEMAGGLUTININ TRI-STALK PROTEIN
Descriptor:Hemagglutinin tri-stalk
Authors:Kirsteina, A., Kazaks, A., Tars, K.
Deposit date:2018-06-01
Release date:2018-10-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and applications of novel influenza HA tri-stalk protein for evaluation of HA stem-specific immunity.
PLoS ONE, 13, 2018
6R1G
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CRYSTAL STRUCTURE OF BORRELIA BURGDORFERI PERIPLASMIC PROTEIN BB0365 (IPLA7, P22)
Descriptor:Outer surface 22 kDa lipoprotein, ZINC ION, TRIETHYLENE GLYCOL, ...
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2019-03-14
Release date:2019-09-18
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural analysis of Borrelia burgdorferi periplasmic lipoprotein BB0365 involved in Lyme disease infection.
Febs Lett., 594, 2020
6FXE
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BBE31 FROM LYME DISEASE AGENT BORRELIA (BORRELIELLA) BURGDORFERI PLAYING A VITAL ROLE IN SUCCESSFUL COLONIZATION OF THE MAMMALIAN HOST
Descriptor:Putative surface protein, GLUTATHIONE
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2018-03-08
Release date:2019-03-20
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione.
Biochim Biophys Acta Gen Subj, 1864, 2019
6FZE
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BBE31 FROM LYME DISEASE AGENT BORRELIA (BORRELIELLA) BURGDORFERI PLAYING A VITAL ROLE IN SUCCESSFUL COLONIZATION OF THE MAMMALIAN HOST (NATIVE DATA)
Descriptor:Putative surface protein, GLUTATHIONE, SULFATE ION
Authors:Brangulis, K., Akopjana, I., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2018-03-14
Release date:2019-03-27
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione.
Biochim Biophys Acta Gen Subj, 1864, 2019
6FZZ
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CRYSTAL STRUCTURE OF BSE31 (BSPA14S_RS05060 GENE PRODUCT) FROM LYME DISEASE AGENT BORRELIA (BORRELIELLA) SPIELMANII
Descriptor:Virulent strain associated lipoprotein, TETRAETHYLENE GLYCOL
Authors:Brangulis, K., Akopjana, I., Kazaks, A., Tars, K.
Deposit date:2018-03-15
Release date:2019-03-27
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione.
Biochim Biophys Acta Gen Subj, 1864, 2019
2YN7
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CRYSTAL STRUCTURE OF AN OUTER SURFACE PROTEIN BBA66 FROM BORRELIA BURGDORFERI
Descriptor:OUTER SURFACE PROTEIN
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Baumanis, V., Tars, K.
Deposit date:2012-10-12
Release date:2013-10-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the Infectious Phenotype-Associated Outer Surface Protein Bba66 from the Lyme Disease Agent Borrelia Burgdorferi.
Ticks Tick Borne Dis., 5, 2014
4ALY
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BORRELIA BURGDORFERI OUTER SURFACE LIPOPROTEIN BBA64
Descriptor:P35 ANTIGEN, SULFATE ION
Authors:Brangulis, K., Tars, K., Petrovskis, I., Kazaks, A., Ranka, R., Baumanis, V.
Deposit date:2012-03-06
Release date:2013-04-17
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of an Outer Surface Lipoprotein Bba64 from the Lyme Disease Agent Borrelia Burgdorferi which is Critical to Ensure Infection After a Tick Bite
Acta Crystallogr.,Sect.D, 69, 2013
4AXZ
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BORRELIA BURGDORFERI OUTER SURFACE LIPOPROTEIN BBA73
Descriptor:PUTATIVE ANTIGEN P35
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Baumanis, V., Tars, K.
Deposit date:2012-06-15
Release date:2013-05-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Characterization of the Borrelia Burgdorferi Outer Surface Protein Bba73 Implicates Dimerization as a Functional Mechanism.
Biochem.Biophys.Res.Commun., 434, 2013
4B2F
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N-TERMINAL DELETION MUTANT OF AN OUTER SURFACE PROTEIN BBA73 FROM BORRELIA BURGDORFERI
Descriptor:PUTATIVE ANTIGEN P35
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2012-07-15
Release date:2013-05-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural Characterization of the Borrelia Burgdorferi Outer Surface Protein Bba73 Implicates Dimerization as a Functional Mechanism.
Biochem.Biophys.Res.Commun., 434, 2013
4BG1
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 1-(3-CARBOXYPROPYL)-1-METHYLPYRROLIDIN-1-IUM CHLORIDE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 1-(3-carboxypropyl)-1-methylpyrrolidin-1-ium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-03-22
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BG5
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LYME DISEASE ASSOCIATED OUTER SURFACE PROTEIN BBA65 FROM BORRELIA BURGDORFERI
Descriptor:BBA65
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2013-03-22
Release date:2014-04-09
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Outer Surface Protein Bba65 from Borrelia Burgdorferi
To be Published
4BGK
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH (3-(TRIMETHYLAMMONIO)PROPYL)PHOSPHINATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, trimethyl(3-oxidanylphosphonoylpropyl)azanium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-03-27
Release date:2014-03-12
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BGM
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 3-CARBOXY-N-(2-FLUOROETHYL)-N,N-DIMETHYLPROPAN-1- AMINIUM CHLORIDE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 3-Carboxy-N-(2-fluoroethyl)-N,N-dimethylpropan-1-aminium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-03-27
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BHF
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 4-(TRIMETHYLAMMONIO)PENTANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 4-(Trimethylammonio)pentanoic acid, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-04-02
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BHG
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 3-(1-ETHYL-1,1-DIMETHYLHYDRAZIN-1-IUM-2-YL)PROPANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 3-(1-Ethyl-1,1-dimethylhydrazin-1-ium-2-yl)propanoic acid, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-04-02
Release date:2014-04-16
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Three Dimensional Structure of Human Gamma-Butyrobetaine Hydroxylase in Complex with 3-(1-Ethyl-1,1-Dimethylhydrazin-1-Ium-2-Yl)Propanoate
To be Published
4BHI
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 3-(1,1,1,2-TETRAMETHYLHYDRAZIN-1-IUM-2-YL)PROPANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 3-(1,1,1,2-TETRAMETHYLHYDRAZIN-1-IUM-2-YL)PROPANOATE, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-04-03
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4BOD
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COMPLEMENT REGULATOR ACQUIRING OUTER SURFACE PROTEIN BBCRASP-4 OR ERPC FROM BORRELIA BURGDORFERI
Descriptor:ERPC
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Baumanis, V., Tars, K.
Deposit date:2013-05-18
Release date:2014-05-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Crystal Structures of the Erp Protein Family Members Erpp and Erpc from Borrelia Burgdorferi Reveal the Reason for Different Affinities for Complement Regulator Factor H.
Biochim.Biophys.Acta, 1854, 2015
4BXM
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COMPLEMENT REGULATOR ACQUIRING OUTER SURFACE PROTEIN BBCRASP-4 OR ERPC FROM BORRELIA BURGDORFERI
Descriptor:ERPC
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Tars, K.
Deposit date:2013-07-13
Release date:2014-07-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structures of the Erp Protein Family Members Erpp and Erpc from Borrelia Burgdorferi Reveal the Reason for Different Affinities for Complement Regulator Factor H.
Biochim.Biophys.Acta, 1854, 2015
4C5W
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THREE DIMENSIONAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE HYDROXYLASE IN COMPLEX WITH 4-(ETHYLDIMETHYLAMMONIO)BUTANOATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, ethyl-dimethyl-(4-oxidanyl-4-oxidanylidene-butyl)azanium, ...
Authors:Tars, K., Leitans, J., Kazaks, A.
Deposit date:2013-09-16
Release date:2014-03-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57, 2014
4CBE
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CRYSTAL STRUCTURE OF COMPLEMENT FACTORS H AND FHL-1 BINDING PROTEIN BBH06 OR CRASP-2 FROM BORRELIA BURGDORFERI (NATIVE)
Descriptor:COMPLEMENT REGULATOR-ACQUIRING SURFACE PROTEIN 2 (CRASP-2)
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Ranka, R., Tars, K.
Deposit date:2013-10-13
Release date:2014-04-16
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural Characterization of Cspz, a Complement Regulator Factor H and Fhl-1 Binding Protein from Borrelia Burgdorferi.
FEBS J., 281, 2014
4D53
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OUTER SURFACE PROTEIN BB0689 FROM BORRELIA BURGDORFERI
Descriptor:BB0689
Authors:Brangulis, K., Petrovskis, I., Kazaks, A., Tars, K.
Deposit date:2014-11-02
Release date:2015-10-14
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Functional Analysis of Bb0689 from Borrelia Burgdorferi, a Member of the Bacterial CAP Superfamily.
J.Struct.Biol., 192, 2015
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