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6JIB
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BU of 6jib by Molmil
Human MTHFD2 in complex with DS44960156
Descriptor: 4-(5-oxo-1,5-dihydro-2H-[1]benzopyrano[3,4-c]pyridine-3(4H)-carbonyl)benzoic acid, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, ...
Authors:Suzuki, M, Matsui, Y, Kawai, J.
Deposit date:2019-02-20
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold.
Acs Med.Chem.Lett., 10, 2019
6JID
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BU of 6jid by Molmil
Human MTHFD2 in complex with Compound 1
Descriptor: 5-(4-oxo-2-phenyl-1,5,7,8-tetrahydropyrido[4,3-d]pyrimidine-6(4H)-carbonyl)-1,3-dihydro-2H-2lambda~6~,1-benzothiazole-2,2-dione, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, ...
Authors:Suzuki, M, Matsui, Y, Matsuhashi, N, Kawai, J.
Deposit date:2019-02-20
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold.
Acs Med.Chem.Lett., 10, 2019
6KG2
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BU of 6kg2 by Molmil
Human MTHFD2 in complex with Compound 18
Descriptor: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, N-[2-chloranyl-4-[[7-methyl-8-(4-methylpiperazin-1-yl)-5-oxidanylidene-2,4-dihydro-1H-chromeno[3,4-c]pyridin-3-yl]carbonyl]phenyl]methanesulfonamide, ...
Authors:Suzuki, M, Matsui, Y, Ota, M, Kawai, J.
Deposit date:2019-07-10
Release date:2019-11-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity.
J.Med.Chem., 62, 2019
1UFN
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BU of 1ufn by Molmil
Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)
Descriptor: putative nuclear protein homolog 5830484A20Rik
Authors:Tochio, N, Kobayashi, N, Koshiba, S, Kigawa, T, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-02
Release date:2004-06-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)
To be Published
1UG7
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BU of 1ug7 by Molmil
Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806
Descriptor: 2610208M17Rik protein
Authors:Li, H, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Shirouzu, M, Terada, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-13
Release date:2004-08-17
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806
To be Published
1UG2
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BU of 1ug2 by Molmil
Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
Descriptor: 2610100B20Rik gene product
Authors:Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-11
Release date:2004-06-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
To be Published
1UGJ
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BU of 1ugj by Molmil
Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16
Descriptor: RIKEN cDNA 2310057J16 protein
Authors:Nagashima, T, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-16
Release date:2004-08-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16
To be Published
1UG8
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BU of 1ug8 by Molmil
NMR structure of the R3H domain from Poly(A)-specific Ribonuclease
Descriptor: Poly(A)-specific Ribonuclease
Authors:Nagata, T, Muto, Y, Hayami, N, Uda, H, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-15
Release date:2004-08-17
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR structure of the R3H domain from Poly(A)-specific Ribonuclease
To be Published
1UH6
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BU of 1uh6 by Molmil
Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06
Descriptor: ubiquitin-like 5
Authors:Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-25
Release date:2003-12-25
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06
To be Published
1UHS
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BU of 1uhs by Molmil
Solution structure of mouse homeodomain-only protein HOP
Descriptor: homeodomain only protein
Authors:Saito, K, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-07-10
Release date:2004-07-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of mouse homeodomain-only protein HOP
To be Published
1UHR
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BU of 1uhr by Molmil
Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
Descriptor: SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily D member 1
Authors:Yamada, K, Saito, K, Nameki, N, Inoue, M, Koshiba, S, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-07-09
Release date:2004-08-24
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
To be Published
1UHW
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BU of 1uhw by Molmil
Solution structure of the DEP domain of mouse pleckstrin
Descriptor: Pleckstrin
Authors:Inoue, K, Yoshida, M, Hatta, R, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-07-11
Release date:2004-01-11
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the DEP domain of mouse pleckstrin
To be Published
1V9J
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BU of 1v9j by Molmil
Solution structure of a BolA-like protein from Mus musculus
Descriptor: BolA-like protein RIKEN cDNA 1110025L05
Authors:Kasai, T, Inoue, M, Koshiba, S, Yabuki, T, Aoki, M, Nunokawa, E, Seki, E, Matsuda, T, Matsuda, N, Tomo, Y, Shirouzu, M, Terada, T, Obayashi, N, Hamana, H, Shinya, N, Tatsuguchi, A, Yasuda, S, Yoshida, M, Hirota, H, Matsuo, Y, Tani, K, Suzuki, H, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-01-26
Release date:2004-02-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of a BolA-like protein from Mus musculus
Protein Sci., 13, 2004
1IVZ
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BU of 1ivz by Molmil
Solution structure of the SEA domain from murine hypothetical protein homologous to human mucin 16
Descriptor: hypothetical protein 1110008I14RIK
Authors:Maeda, T, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-04-02
Release date:2002-10-02
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16)
J.Biol.Chem., 279, 2004
1UKX
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BU of 1ukx by Molmil
Solution structure of the RWD domain of mouse GCN2
Descriptor: GCN2 eIF2alpha kinase
Authors:Nameki, N, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-09-03
Release date:2004-08-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the RWD domain of the mouse GCN2 protein.
Protein Sci., 13, 2004
1UGO
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BU of 1ugo by Molmil
Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5
Descriptor: Bcl2-associated athanogene 5
Authors:Endoh, H, Hayashi, F, Seimiya, K, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-17
Release date:2004-08-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010

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