Author results

2H63
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CRYSTAL STRUCTURE OF HUMAN BILIVERDIN REDUCTASE A
Descriptor:Biliverdin reductase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kavanagh, K., Elkins, J., Ugochukwu, E., Guo, K., Pilka, E., Lukacik, P., Smee, C., Papagrigoriou, E., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-05-30
Release date:2006-07-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Biliverdin Reductase A
To be Published
1XG5
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STRUCTURE OF HUMAN PUTATIVE DEHYDROGENASE MGC4172 IN COMPLEX WITH NADP
Descriptor:ARPG836, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETIC ACID
Authors:Kavanagh, K., Ng, S., Sharma, S., Vedadi, M., von Delft, F., Walker, J.R., dhe Paganon, S., Bray, J., Oppermann, U., Edwards, A., Arrowsmith, C., Sundstrom, M., Structural Genomics Consortium (SGC)
Deposit date:2004-09-16
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural Genomics Consortium: Structure of the putative human dehydrogenase MGC4172
To be Published
2BEL
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STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE
Descriptor:CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CARBENOXOLONE, ...
Authors:Kavanagh, K., Wu, X., Svensson, S., Elleby, B., von Delft, F., Debreczeni, J.E., Sharma, S., Bray, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Abrahmsen, L., Oppermann, U.
Deposit date:2004-11-25
Release date:2004-12-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:The High Resolution Structures of Human, Murine and Guinea Pig 11-Beta-Hydroxysteroid Dehydrogenase Type 1 Reveal Critical Differences in Active Site Architecture
To be Published
1YDE
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CRYSTAL STRUCTURE OF HUMAN RETINAL SHORT-CHAIN DEHYDROGENASE/REDUCTASE 3
Descriptor:Retinal dehydrogenase/reductase 3
Authors:Lukacik, P., Bunkozci, G., Kavanagh, K., Sundstrom, M., Arrowsmith, C., Edwards, A., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2004-12-23
Release date:2005-01-18
Last modified:2012-03-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.
Biochem.J., 402, 2007
1ZSX
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CRYSTAL STRUCTURE OF HUMAN POTASSIUM CHANNEL KV BETA-SUBUNIT (KCNAB2)
Descriptor:Voltage-gated potassium channel beta-2 subunit, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wennerstrand, P., Johannsson, I., Ugochukwu, E., Kavanagh, K., Edwards, A., Arrowsmith, C., Williams, L., Sundstrom, M., Guo, K., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-05-25
Release date:2005-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2)
To be Published
2FVL
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CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE (AKR1C4) COMPLEXED WITH NADP+
Descriptor:Aldo-keto reductase family 1, member C4, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ugochukwu, E., Smee, C., Guo, K., Lukacik, P., Kavanagh, K., Debreczeni, J.E., von Delft, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-01-31
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (AKR1C4) complexed with NADP+
To be Published
2IZZ
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CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE REDUCTASE
Descriptor:PYRROLINE-5-CARBOXYLATE REDUCTASE 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL
Authors:Pike, A.C.W., Guo, K., Kavanagh, K., Pilka, E.S., Berridge, G., Colebrook, S., Bray, J., Salah, E., Savitsky, P., Papagrigoriou, E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U.
Deposit date:2006-07-31
Release date:2006-08-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Human Pyrroline-5-Carboxylate Reductase
To be Published
3K1Z
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CRYSTAL STRUCTURE OF HUMAN HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 3 (HDHD3)
Descriptor:Haloacid dehalogenase-like hydrolase domain-containing protein 3, 1,2-ETHANEDIOL, GLYCEROL
Authors:Ugochukwu, E., Guo, K., Yue, W.W., Pilka, E., Picaud, S., Muniz, J., Pike, A.C.W., Krojer, T., Gomes, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-09-29
Release date:2009-11-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of Human Haloacid Dehalogenase-like Hydrolase Domain containing 3 (HDHD3)
To be Published
3OOY
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CRYSTAL STRUCTURE OF HUMAN TRANSKETOLASE (TKT)
Descriptor:Transketolase, THIAMIN DIPHOSPHATE, CALCIUM ION, ...
Authors:Krojer, T., Krysztofinska, E., Guo, K., Pilka, E., Kochan, G., Chaikuad, A., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2010-08-31
Release date:2010-11-17
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of human Transketolase (TKT)
To be Published
2CLP
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CRYSTAL STRUCTURE OF HUMAN AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3
Descriptor:AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION
Authors:Debreczeni, J.E., Marsden, B.D., Johansson, C., Kavanagh, K., Guo, K., Smee, C., Gileadi, O., Turnbull, A., Papagrigoriou, E., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Oppermann, U.
Deposit date:2006-04-28
Release date:2006-05-12
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Human Aflatoxin B1 Aldehyde Reductase Member 3
To be Published
1YB1
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CRYSTAL STRUCTURE OF HUMAN 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE XI
Descriptor:17-beta-hydroxysteroid dehydrogenase type XI, CHLORIDE ION, SULFATE ION, ...
Authors:Lukacik, P., Bunkoczi, G., Kavanagh, K., Ng, S., von Delft, F., Bray, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2004-12-18
Release date:2004-12-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of human 17-beta-hydroxysteroid dehydrogenase type XI.
To be Published
1YB5
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CRYSTAL STRUCTURE OF HUMAN ZETA-CRYSTALLIN WITH BOUND NADP
Descriptor:Quinone oxidoreductase, ACETATE ION, CHLORIDE ION, ...
Authors:Debreczeni, J., Berridge, G., Kavanagh, K., Colbrook, S., Bray, J., Williams, L., Oppermann, U., Sundstrom, M., Arrowsmith, C., Edwards, A., Gileadi, O., von Delft, F., Structural Genomics Consortium (SGC)
Deposit date:2004-12-20
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of human Zeta-Crystallin at 1.85A
To be Published
1Z6Z
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CRYSTAL STRUCTURE OF HUMAN SEPIAPTERIN REDUCTASE IN COMPLEX WITH NADP+
Descriptor:Sepiapterin reductase, SULFATE ION, CHLORIDE ION, ...
Authors:Ugochukwu, E., Kavanagh, K., Ng, S., Arrowsmith, C., Edwards, A., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-03-23
Release date:2005-04-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Human Sepiapterin Reductase
To be Published
1ZBQ
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CRYSTAL STRUCTURE OF HUMAN 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 4 IN COMPLEX WITH NAD
Descriptor:17-beta-hydroxysteroid dehydrogenase 4, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Lukacik, P., Shafqat, N., Kavanagh, K., Bray, J., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-04-08
Release date:2005-04-26
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal Structure Of Human 17-Beta-Hydroxysteroid Dehydrogenase Type 4 In Complex With NAD
To be Published
1ZX1
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HUMAN QUINONE OXIDOREDUCTASE 2 (NQO2) IN COMPLEX WITH THE CYTOSTATIC PRODRUG CB1954
Descriptor:NRH dehydrogenase [quinone] 2, ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Jansson, A., Wu, X., Kavanagh, K., Kerr, D., Knox, R., Walton, R., Gunther, U., Ludwig, C., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-06-06
Release date:2005-06-14
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954
To be Published
2B69
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CRYSTAL STRUCTURE OF HUMAN UDP-GLUCORONIC ACID DECARBOXYLASE
Descriptor:UDP-glucuronate decarboxylase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE
Authors:Ugochukwu, E., Dubinina, E., Kavanagh, K., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2005-09-30
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal Structure of Human UDP-glucoronic acid decarboxylase
To be Published
2BP1
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STRUCTURE OF THE AFLATOXIN ALDEHYDE REDUCTASE IN COMPLEX WITH NADPH
Descriptor:AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRATE ANION
Authors:Debreczeni, J.E., Lukacik, P., Kavanagh, K., Dubinina, E., Bray, J., Colebrook, S., Haroniti, A., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Gileadi, O., Oppermann, U.
Deposit date:2005-04-17
Release date:2005-05-11
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Aflatoxin Aldehyde Reductase in Complex with Nadph
To be Published
2BUJ
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CRYSTAL STRUCTURE OF THE HUMAN SERINE-THREONINE KINASE 16 IN COMPLEX WITH STAUROSPORINE
Descriptor:SERINE/THREONINE-PROTEIN KINASE 16, CHLORIDE ION, STAUROSPORINE
Authors:Debreczeni, J.E., Eswaran, J., Bullock, A., Filippakopoulos, P., Kavanagh, K., Amos, A., Fedorov, O., Sobott, F., Ball, L.J., von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Knapp, S.
Deposit date:2005-06-13
Release date:2005-07-05
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Human Serine-Threonine Kinase 16 in Complex with Staurosporine
To be Published
2CFY
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CRYSTAL STRUCTURE OF HUMAN THIOREDOXIN REDUCTASE 1
Descriptor:THIOREDOXIN REDUCTASE 1, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Debreczeni, J.E., Johansson, C., Kavanagh, K., Savitsky, P., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U.
Deposit date:2006-02-26
Release date:2006-03-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Thioredoxin Reductase 1
To be Published
2H5G
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CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE SYNTHETASE
Descriptor:Delta 1-pyrroline-5-carboxylate synthetase, SULFATE ION
Authors:Papagrigoriou, E., Shafqat, N., Turnbull, A.P., Berridge, G., Hozjan, V., Kavanagh, K., Gileadi, O., Smee, C., Bray, J., Gorrec, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-05-26
Release date:2006-06-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of human pyrroline-5-carboxylate synthetase
To be published
2HW5
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THE CRYSTAL STRUCTURE OF HUMAN ENOYL-COENZYME A (COA) HYDRATASE SHORT CHAIN 1, ECHS1
Descriptor:Enoyl-CoA hydratase, MAGNESIUM ION, CROTONYL COENZYME A
Authors:Turnbull, A.P., Salah, E., Niesen, F., Debreczeni, J., Ugochukwu, E., Pike, A.C.W., Kavanagh, K., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-07-31
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
To be Published
2IIK
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CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL ACETYL-COA ACYL TRANSFERASE 1 (ACAA1)
Descriptor:3-ketoacyl-CoA thiolase, peroxisomal
Authors:Papagrigoriou, E., Johansson, C., Smee, C., Kavanagh, K., Pike, A.C.W., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C.H., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-09-28
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1)
TO BE PUBLISHED
2JFK
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STRUCTURE OF THE MAT DOMAIN OF HUMAN FAS WITH MALONYL-COA
Descriptor:FATTY ACID SYNTHASE, COENZYME A
Authors:Bunkoczi, G., Kavanagh, K., Hozjan, V., Rojkova, A., Watt, S., Wu, X., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Smith, S., Oppermann, U.
Deposit date:2007-02-02
Release date:2007-03-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the MAT Domain of Human Fas with Malonyl-Coa
To be Published
2NZL
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CRYSTAL STRUCTURE OF HUMAN HYDROXYACID OXIDASE 1
Descriptor:Hydroxyacid oxidase 1, FLAVIN MONONUCLEOTIDE, GLYOXYLIC ACID
Authors:Ugochukwu, E., Kavanagh, K., Pilka, E., Berridge, G., Debreczeni, J.E., Papagrigoriou, E., Turnbull, A., Niesen, F., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2006-11-24
Release date:2006-12-12
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of human hydroxyacid oxidase 1
To be Published
2PLA
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CRYSTAL STRUCTURE OF HUMAN GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN
Descriptor:Glycerol-3-phosphate dehydrogenase 1-like protein, PHOSPHATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Uppenberg, J., Smee, C., Hozjan, V., Kavanagh, K., Bunkoczi, G., Papagrigoriou, E., Pike, A.C.W., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-04-19
Release date:2007-05-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of human glycerol-3-phosphate dehydrogenase 1-like protein.
To be Published
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