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7V4G
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BU of 7v4g by Molmil
Crystal structure of human ALKBH5 in complex with m6A-containing ssRNA
Descriptor: GLYCEROL, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2021-08-13
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
7WL0
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BU of 7wl0 by Molmil
Crystal structure of human ALKBH5 in complex with N-oxalylglycine (NOG) and m6A-containing ssRNA
Descriptor: FORMIC ACID, MANGANESE (II) ION, N-OXALYLGLYCINE, ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2022-01-12
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
7WKV
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BU of 7wkv by Molmil
Crystal structure of human ALKBH5 in complex with 2-oxoglutarate (2OG) and m6A-containing ssRNA
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ...
Authors:Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S.
Deposit date:2022-01-11
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes.
Nucleic Acids Res., 50, 2022
1ZC8
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BU of 1zc8 by Molmil
Coordinates of tmRNA, SmpB, EF-Tu and h44 fitted into Cryo-EM map of the 70S ribosome and tmRNA complex
Descriptor: Elongation factor Tu, H2 16S rRNA, H2b d mRNA, ...
Authors:Valle, M, Gillet, R, Kaur, S, Henne, A, Ramakrishnan, V, Frank, J.
Deposit date:2005-04-11
Release date:2005-04-19
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Visualizing tmRNA Entry into a Stalled Ribosome
Science, 300, 2003
7SXQ
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BU of 7sxq by Molmil
Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag
Descriptor: 1,2-ETHANEDIOL, Apicoplast DNA polymerase, CHLORIDE ION, ...
Authors:Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R.
Deposit date:2021-11-24
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum.
Eur.J.Med.Chem., 243, 2022
7SXL
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BU of 7sxl by Molmil
Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R.
Deposit date:2021-11-23
Release date:2022-10-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum.
Eur.J.Med.Chem., 243, 2022
6FYY
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BU of 6fyy by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FYX
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BU of 6fyx by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
3T07
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BU of 3t07 by Molmil
Crystal structure of S. aureus Pyruvate Kinase in complex with a naturally occurring bis-indole alkaloid
Descriptor: (3S,5R)-3,5-bis(6-bromo-1H-indol-3-yl)piperazin-2-one, PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
3T05
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BU of 3t05 by Molmil
Crystal structure of S. aureus Pyruvate Kinase
Descriptor: PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
2OB7
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BU of 2ob7 by Molmil
Structure of tmRNA-(SmpB)2 complex as inferred from cryo-EM
Descriptor: 16S ribosomal RNA, SsrA-binding protein, transfer-messenger RNA
Authors:Frank, J, Felden, B, Gillet, R, Li, W.
Deposit date:2006-12-18
Release date:2007-01-23
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:Scaffolding as an organizing principle in trans-translation. The roles of small protein B and ribosomal protein S1.
J.Biol.Chem., 282, 2007
3T0T
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BU of 3t0t by Molmil
Crystal structure of S. aureus Pyruvate Kinase
Descriptor: N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-20
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.
Acs Chem.Biol., 7, 2012

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PDB entries from 2024-03-27

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