6R83
| CryoEM structure and molecular model of squid hemocyanin (Todarodes pacificus , TpH) | Descriptor: | Hemocyanin subunit 1 | Authors: | Tanaka, Y, Kato, S, Stabrin, M, Raunser, S, Matsui, T, Gatsogiannis, C. | Deposit date: | 2019-03-31 | Release date: | 2019-05-08 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Cryo-EM reveals the asymmetric assembly of squid hemocyanin. Iucrj, 6, 2019
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4TV7
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1LUE
| RECOMBINANT SPERM WHALE MYOGLOBIN H64D/V68A/D122N MUTANT (MET) | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Phillips Jr, G.N. | Deposit date: | 2002-05-22 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular engineering of myoglobin: influence of residue 68 on the rate and the
enantioselectivity of oxidation reactions catalyzed by H64D/V68X myoglobin Biochemistry, 42, 2003
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1O16
| RECOMBINANT SPERM WHALE MYOGLOBIN H64D/V68S/D122N MUTANT (MET) | Descriptor: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Phillips Jr, G.N. | Deposit date: | 2002-10-25 | Release date: | 2003-11-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular engineering of myoglobin: influence of residue 68 on the rate and the
enantioselectivity of oxidation reactions catalyzed by H64D/V68X myoglobin Biochemistry, 42, 2003
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4YD9
| Crystal structure of squid hemocyanin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CU2-O2 CLUSTER, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Matsuno, A, Gai, Z, Kato, K, Tanaka, Y, Yao, M. | Deposit date: | 2015-02-21 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of the 3.8-MDa Respiratory Supermolecule Hemocyanin at 3.0 angstrom Resolution Structure, 23, 2015
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8JYG
| Crystal structure of Human HPSE1 in complex with inhibitor | Descriptor: | (5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-2-[2-(3-phenoxyphenyl)ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Mima, M, Fujimoto, N, Imai, Y. | Deposit date: | 2023-07-03 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based lead optimization to improve potency and selectivity of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid series of heparanase-1 inhibitor. Bioorg.Med.Chem., 93, 2023
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7YJC
| Crystal structure of Human HPSE1 in complex with inhibitor | Descriptor: | (5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid, Heparanase 50 kDa subunit, Heparanase 8 kDa subunit | Authors: | Mima, M, Fujimoto, N, Imai, Y. | Deposit date: | 2022-07-19 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor. Bioorg.Med.Chem.Lett., 79, 2022
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7YI7
| Crystal structure of Human HPSE1 in complex with inhibitor | Descriptor: | (5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-2-[2-[4-(trifluoromethyl)phenyl]ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid, Heparanase 50 kDa subunit, Heparanase 8 kDa subunit | Authors: | Mima, M, Fujimoto, N, Imai, Y. | Deposit date: | 2022-07-15 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor. Bioorg.Med.Chem.Lett., 79, 2022
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8K5Y
| Crystal structure of human proMMP-9 catalytic domain in complex with inhibitor | Descriptor: | (3-azanyl-4-fluoranyl-5,7,8,9-tetrahydropyrido[4,3-c]azepin-6-yl)-[6-(2-oxidanylpropan-2-yl)-1H-indol-2-yl]methanone, CALCIUM ION, DIHYDROGENPHOSPHATE ION, ... | Authors: | Kamitani, M, Mima, M, Nishikawa-Shimono, R. | Deposit date: | 2023-07-24 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Discovery of novel indole derivatives as potent and selective inhibitors of proMMP-9 activation. Bioorg.Med.Chem.Lett., 97, 2023
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8K5X
| Crystal structure of human proMMP-9 catalytic domain in complex with inhibitor | Descriptor: | (6-cyclopropyl-1~{H}-indol-2-yl)-(5,7,8,9-tetrahydropyrido[4,3-c]azepin-6-yl)methanone, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kamitani, M, Mima, M, Nishikawa-Shimono, R. | Deposit date: | 2023-07-24 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of novel indole derivatives as potent and selective inhibitors of proMMP-9 activation. Bioorg.Med.Chem.Lett., 97, 2023
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8K5W
| Crystal structure of human proMMP-9 catalytic domain in complex with inhibitor | Descriptor: | 2-[[5-fluoranyl-7-(methylamino)-1H-indol-2-yl]carbonyl]-N-(2-pyrrol-1-ylethyl)-3,4-dihydro-1H-isoquinoline-7-carboxamide, CALCIUM ION, DIHYDROGENPHOSPHATE ION, ... | Authors: | Kamitani, M, Mima, M, Nishikawa-Shimono, R. | Deposit date: | 2023-07-24 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of novel indole derivatives as potent and selective inhibitors of proMMP-9 activation. Bioorg.Med.Chem.Lett., 97, 2023
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8K5V
| Crystal structure of human proMMP-9 catalytic domain in complex with inhibitor | Descriptor: | 6,7-dihydro-4H-[1,3]oxazolo[4,5-c]pyridin-5-yl-(7-ethyl-2H-indazol-3-yl)methanone, CALCIUM ION, DIHYDROGENPHOSPHATE ION, ... | Authors: | Kamitani, M, Mima, M, Nishikawa-Shimono, R. | Deposit date: | 2023-07-24 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of novel indole derivatives as potent and selective inhibitors of proMMP-9 activation. Bioorg.Med.Chem.Lett., 97, 2023
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7CJ4
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7CJ9
| Crystal structure of N-terminal His-tagged D-allulose 3-epimerase from Methylomonas sp. with additional C-terminal residues | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-fructose, ... | Authors: | Yoshida, H, Yoshihara, A, Kamitori, S. | Deposit date: | 2020-07-09 | Release date: | 2021-04-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp. Febs Open Bio, 11, 2021
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7CJ7
| Crystal structure of homo dimeric D-allulose 3-epimerase from Methylomonas sp. in complex with L-tagatose | Descriptor: | (2R,3R,4R,5S)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol, Epimerase, L-sorbose, ... | Authors: | Yoshida, H, Yoshihara, A, Kamitori, S. | Deposit date: | 2020-07-09 | Release date: | 2021-04-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.695 Å) | Cite: | Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp. Febs Open Bio, 11, 2021
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7CJ6
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7CJ8
| Crystal structure of N-terminal His-tagged D-allulose 3-epimerase from Methylomonas sp. in complex with D-allulose | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-psicose, Epimerase, ... | Authors: | Yoshida, H, Yoshihara, A, Kamitori, S. | Deposit date: | 2020-07-09 | Release date: | 2021-04-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp. Febs Open Bio, 11, 2021
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7CJ5
| Crystal structure of homo dimeric D-allulose 3-epimerase from Methylomonas sp. in complex with D-fructose | Descriptor: | D-fructose, Epimerase, MAGNESIUM ION, ... | Authors: | Yoshida, H, Yoshihara, A, Kamitori, S. | Deposit date: | 2020-07-09 | Release date: | 2021-04-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp. Febs Open Bio, 11, 2021
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5ZL6
| Histidine Racemase from Leuconostoc mesenteroides subsp. sake NBRC 102480 | Descriptor: | Histidine racemase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Adachi, M, Shimizu, R, Oikawa, T. | Deposit date: | 2018-03-27 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The first identification and characterization of a histidine-specific amino acid racemase, histidine racemase from a lactic acid bacterium, Leuconostoc mesenteroides subsp. sake NBRC 102480. Amino Acids, 51, 2019
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1I29
| CRYSTAL STRUCTURE OF CSDB COMPLEXED WITH L-PROPARGYLGLYCINE | Descriptor: | (2S)-2-aminobut-3-ynoic acid, CSDB, PYRIDOXAL-5'-PHOSPHATE | Authors: | Mihara, H, Fujii, T, Kurihara, T, Hata, Y, Esaki, N. | Deposit date: | 2001-02-07 | Release date: | 2003-07-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: implications for its specificity toward
selenocysteine. J.BIOCHEM.(TOKYO), 131, 2002
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7WXT
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7WXS
| Lysozyme protected by polyacrylamide gel | Descriptor: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | Authors: | Muroyama, H, Tomoike, F, Nagae, T, Okada, T. | Deposit date: | 2022-02-15 | Release date: | 2023-02-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Post-crystallization protection of protein crystals by polyacrylamide To Be Published
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