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2QY0
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ACTIVE DIMERIC STRUCTURE OF THE CATALYTIC DOMAIN OF C1R REVEALS ENZYME-PRODUCT LIKE CONTACTS
Descriptor:Complement C1r subcomponent, GLYCEROL
Authors:Kardos, J., Harmat, V., Pallo, A., Barabas, O., Szilagyi, K., Graf, L., Naray-Szabo, G., Goto, Y., Zavodszky, P., Gal, P.
Deposit date:2007-08-13
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r.
Mol.Immunol., 45, 2008
1Q3X
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CRYSTAL STRUCTURE OF THE CATALYTIC REGION OF HUMAN MASP-2
Descriptor:Mannan-binding lectin serine protease 2, SODIUM ION, GLYCEROL
Authors:Harmat, V., Gal, P., Kardos, J., Szilagyi, K., Ambrus, G., Naray-Szabo, G., Zavodszky, P.
Deposit date:2003-08-01
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions
J.Mol.Biol., 342, 2004
3IF7
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STRUCTURE OF CALMODULIN COMPLEXED WITH ITS FIRST ENDOGENOUS INHIBITOR, SPHINGOSYLPHOSPHORYLCHOLINE
Descriptor:Calmodulin, CALCIUM ION, 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium
Authors:Kovacs, E., Harmat, V., Toth, J., Vertessy, B.G., Modos, K., Kardos, J., Liliom, K.
Deposit date:2009-07-24
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions
Faseb J., 24, 2010
4BNR
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EXTREMELY STABLE COMPLEX OF CRAYFISH TRYPSIN WITH BOVINE TRYPSIN INHIBITOR
Descriptor:HEPATOPANCREAS TRYPSIN, PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, ...
Authors:Molnar, T., Voros, J., Szeder, B., Takats, K., Kardos, J., Katona, G., Graf, L.
Deposit date:2013-05-17
Release date:2013-09-04
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Comparison of Complexes Formed by a Crustacean and a Vertebrate Trypsin with Bovine Pancreatic Trypsin Inhibitor - the Key to Achieving Extreme Stability?
FEBS J., 280, 2013
2XTT
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BOVINE TRYPSIN IN COMPLEX WITH EVOLUTIONARY ENHANCED SCHISTOCERCA GREGARIA PROTEASE INHIBITOR 1 (SGPI-1-P02)
Descriptor:PROTEASE INHIBITOR SGPI-1, CATIONIC TRYPSIN, CALCIUM ION, ...
Authors:Wahlgren, W.Y., Pal, G., Kardos, J., Porrogi, P., Szenthe, B., Patthy, A., Graf, L., Katona, G.
Deposit date:2010-10-12
Release date:2010-11-10
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:The Catalytic Aspartate is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-Like Inhibitor: A Refined Mechanism of Serine Protease Action.
J.Biol.Chem., 286, 2011
2F91
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1.2A RESOLUTION STRUCTURE OF A CRAYFISH TRYPSIN COMPLEXED WITH A PEPTIDE INHIBITOR, SGTI
Descriptor:hepatopancreas trypsin, Serine protease inhibitor I/II, CADMIUM ION, ...
Authors:Fodor, K., Harmat, V., Hetenyi, C., Kardos, J., Antal, J., Perczel, A., Patthy, A., Katona, G., Graf, L.
Deposit date:2005-12-05
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis.
Biochemistry, 45, 2006
3BAS
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF THE SCALLOP MYOSIN ROD, MONOCLINIC (C2) FORM
Descriptor:Myosin heavy chain, striated muscle/General control protein GCN4 chimera, IODIDE ION
Authors:Brown, J.H., Cohen, C.
Deposit date:2007-11-08
Release date:2008-01-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins.
J.Mol.Biol., 375, 2008
3BAT
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF THE SCALLOP MYOSIN ROD, MONOCLINIC (P21) FORM
Descriptor:Myosin heavy chain, striated muscle/General control protein GCN4
Authors:Brown, J.H., Cohen, C.
Deposit date:2007-11-08
Release date:2008-01-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins.
J.Mol.Biol., 375, 2008
1ZJK
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CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC REGION OF HUMAN MASP-2
Descriptor:Mannan-binding lectin serine protease 2
Authors:Gal, P., Harmat, V., Kocsis, A., Bian, T., Barna, L., Ambrus, G., Vegh, B., Balczer, J., Sim, R.B., Naray-Szabo, G., Zavodszky, P.
Deposit date:2005-04-29
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A True Autoactivating Enzyme: Structural insight into mannose-binding lectin-associated serine protease-2 activations
J.Biol.Chem., 280, 2005