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1SEG
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BU of 1seg by Molmil
Crystal structure of a toxin chimera between Lqh-alpha-IT from the scorpion Leiurus quinquestriatus hebraeus and AAH2 from Androctonus australis hector
Descriptor: AAH2: LQH-ALPHA-IT (FACE) CHIMERIC TOXIN, NITRATE ION, PROPANOIC ACID, ...
Authors:Karbat, I, Frolow, F, Froy, O, Gilles, N, Cohen, L, Turkov, M, Gordon, D, Gurevitz, M.
Deposit date:2004-02-17
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular basis of the high insecticidal potency of scorpion alpha-toxins.
J.Biol.Chem., 279, 2004
6Q61
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BU of 6q61 by Molmil
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
Descriptor: Kunitz-type conkunitzin-S1, SULFATE ION
Authors:Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E.
Deposit date:2018-12-10
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Q6C
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BU of 6q6c by Molmil
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
Descriptor: 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ...
Authors:Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E.
Deposit date:2018-12-10
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Pore-modulating toxins exploit inherent slow inactivation to block K+channels.
Proc.Natl.Acad.Sci.USA, 116, 2019
2I61
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BU of 2i61 by Molmil
Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ...
Authors:Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D.
Deposit date:2006-08-27
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity.
J.Mol.Biol., 366, 2007
6ZOI
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BU of 6zoi by Molmil
A lid blocking mechanism of a cone snail toxin revealed at the atomic level
Descriptor: Conknunitzin-C3 mutante
Authors:Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I.
Deposit date:2020-07-07
Release date:2021-07-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:A lid blocking mechanism of a cone snail toxin revealed at the atomic level
To Be Published
6YHT
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BU of 6yht by Molmil
A lid blocking mechanism of a cone snail toxin revealed at the atomic level
Descriptor: CITRIC ACID, Conk-C1, SULFATE ION
Authors:Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I.
Deposit date:2020-03-31
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide.
J.Mol.Biol., 433, 2021
6YHY
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BU of 6yhy by Molmil
A lid blocking mechanism of a cone snail toxin revealed at the atomic level
Descriptor: Conk-S1
Authors:Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I.
Deposit date:2020-03-31
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A Molecular Lid Mechanism of K + Channel Blocker Action Revealed by a Cone Peptide.
J.Mol.Biol., 433, 2021
2ATB
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BU of 2atb by Molmil
Triple mutant 8D9D10V of scorpion toxin LQH-alpha-IT
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, NITRATE ION, ...
Authors:Kahn, R, Karbat, I, Gurevitz, M, Frolow, F.
Deposit date:2005-08-24
Release date:2006-09-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
2ASC
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BU of 2asc by Molmil
Scorpion toxin LQH-alpha-IT
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ...
Authors:Kahn, R, Karbat, I, Gurevitz, M, Frolow, F.
Deposit date:2005-08-23
Release date:2006-09-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:X-ray structures of Lqh-alpha-IT and Lqh-alpha-IT8D9D10V mutant
To be Published
6O2W
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BU of 6o2w by Molmil
Crystal structure of the SARAF luminal domain Cys-lock mutant dimer
Descriptor: GLYCEROL, Store-operated calcium entry-associated regulatory factor
Authors:Kimberlin, C.R, Minor, D.L.
Deposit date:2019-02-24
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped beta-Sandwich Fold Important for SOCE Modulation.
J.Mol.Biol., 431, 2019
6O2U
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BU of 6o2u by Molmil
Crystal structure of the SARAF luminal domain
Descriptor: Store-operated calcium entry-associated regulatory factor
Authors:Kimberlin, C.R, Minor, D.L.
Deposit date:2019-02-24
Release date:2019-05-29
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped beta-Sandwich Fold Important for SOCE Modulation.
J.Mol.Biol., 431, 2019
6O2V
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BU of 6o2v by Molmil
Crystal structure of the SARAF luminal domain Cys-lock mutant monomer
Descriptor: FORMIC ACID, GLYCEROL, Store-operated calcium entry-associated regulatory factor
Authors:Kimberlin, C.R, Minor, D.L.
Deposit date:2019-02-24
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped beta-Sandwich Fold Important for SOCE Modulation.
J.Mol.Biol., 431, 2019

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PDB entries from 2024-03-27

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