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6Z26
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BU of 6z26 by Molmil
Structure of the Danio rerio SAS-6 coiled-coil domain
Descriptor: Spindle assembly abnormal protein 6 homolog
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-05-15
Release date:2021-05-26
Last modified:2022-05-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 30, 2022
5JTU
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BU of 5jtu by Molmil
Crystal structure of GPb in complex with 8b
Descriptor: (1S)-1,5-anhydro-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]-D-glucitol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ...
Authors:Kantsadi, A.L, Stravodimos, G.A, Chatzileontiadou, D.S.M, Leonidas, D.D.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
Eur.J.Med.Chem., 123, 2016
5JTT
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BU of 5jtt by Molmil
Crystal structure of GPb in complex with 8a
Descriptor: (1S)-1,5-anhydro-1-(5-phenyl-1H-imidazol-2-yl)-D-glucitol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ...
Authors:Kantsadi, A.L, Stravodimos, G.A, Chatzileontiadou, D.S.M, Leonidas, D.D.
Deposit date:2016-05-09
Release date:2016-08-24
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
Eur.J.Med.Chem., 123, 2016
6YRL
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BU of 6yrl by Molmil
Structure of the Chlamydomonas reinhardtii SAS-6 coiled-coil domain, C2 crystal form
Descriptor: Centriole protein
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2022-03-16
Method:X-RAY DIFFRACTION (2.343 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
6YRN
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BU of 6yrn by Molmil
Structure of the Chlamydomonas reinhardtii SAS-6 coiled-coil domain, P2 crystal form
Descriptor: Centriole protein, TETRAETHYLENE GLYCOL
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
6YS4
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BU of 6ys4 by Molmil
Structure of the Homo sapiens SAS-6 coiled-coil domain
Descriptor: GLYCINE, Spindle assembly abnormal protein 6 homolog, TETRAETHYLENE GLYCOL
Authors:Kantsadi, A.L, Vakonakis, I.
Deposit date:2020-04-21
Release date:2021-05-12
Last modified:2022-03-16
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
3T3I
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BU of 3t3i by Molmil
Glycogen Phosphorylase b in complex with GlcCF3U
Descriptor: 1-(beta-D-glucopyranosyl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2011-07-25
Release date:2012-02-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3G
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BU of 3t3g by Molmil
Glycogen Phosphorylase b in complex with GlcBrU
Descriptor: 5-bromo-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2011-07-25
Release date:2012-02-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3E
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BU of 3t3e by Molmil
Glycogen phosphorylase b in complex with GlcClU
Descriptor: 5-chloro-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2011-07-25
Release date:2012-02-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3H
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BU of 3t3h by Molmil
Glycogen Phosphorylase b in complex with GlcIU
Descriptor: 1-(beta-D-glucopyranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2011-07-25
Release date:2012-02-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
3T3D
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BU of 3t3d by Molmil
Glycogen phosphorylase b in complex with GlcU
Descriptor: 1-beta-D-glucopyranosylpyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2011-07-25
Release date:2012-02-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase  b
Chemmedchem, 7, 2012
5LRC
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BU of 5lrc by Molmil
Crystal structure of Glycogen Phosphorylase in complex with KS114
Descriptor: (1S)-1,5-anhydro-1-(5-phenyl-4H-1,2,4-triazol-3-yl)-D-glucitol, Glycogen phosphorylase, muscle form, ...
Authors:Kantsadi, A.L, Stravodimos, G.A, Chatzileontiadou, D.S.M, Leonidas, D.D.
Deposit date:2016-08-18
Release date:2017-06-14
Last modified:2020-08-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J. Struct. Biol., 199, 2017
5LRD
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BU of 5lrd by Molmil
Crystal structure of Glycogen Phosphorylase b in complex with KS242
Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methylphenyl)-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ...
Authors:Kantsadi, A.L, Leonidas, D.D.
Deposit date:2016-08-18
Release date:2017-06-14
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J. Struct. Biol., 199, 2017
5LRE
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BU of 5lre by Molmil
Crystal structure of Glycogen Phosphorylase b in complex with KS382
Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ...
Authors:Kantsadi, A.L, Stravodimos, G.A, Kyriakis, E, Chatzileontiadou, D.S.M, Leonidas, D.D.
Deposit date:2016-08-18
Release date:2017-05-31
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
Eur J Med Chem, 123, 2016
5LRF
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BU of 5lrf by Molmil
Crystal structure of Glycogen Phosphorylase b in complex with KS389
Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ...
Authors:Kantsadi, A.L, Leonidas, D.D.
Deposit date:2016-08-18
Release date:2017-06-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J. Struct. Biol., 199, 2017
4YI3
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BU of 4yi3 by Molmil
Crystal structure of Gpb in complex with 4a
Descriptor: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ...
Authors:Kantsadi, A.L, Chatzileontiadou, D.S.M, Stravodimos, G.A, Leonidas, D.D.
Deposit date:2015-02-27
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N -( beta-D-glucopyranosyl) urea inhibitors.
Curr Top Med Chem, 15, 2015
4YI5
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BU of 4yi5 by Molmil
Crystal structure of Gpb in complex with 4b
Descriptor: Glycogen phosphorylase, muscle form, INOSINIC ACID, ...
Authors:Kantsadi, A.L, Chatzileontiadou, D.S.M, Stravodimos, G.A, Leonidas, D.D.
Deposit date:2015-02-27
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glycogen phosphorylase as a target for type 2 diabetes: synthetic, biochemical, structural and computational evaluation of novel N-acyl-N -( beta-D-glucopyranosyl) urea inhibitors.
Curr Top Med Chem, 15, 2015
4EJ2
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BU of 4ej2 by Molmil
Crystal structure of GPb in complex with DK10
Descriptor: 1-(beta-D-glucopyranosyl)-5-(hept-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2012-04-06
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.
Eur.J.Med.Chem., 54, 2012
4EL5
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BU of 4el5 by Molmil
Crystal structure of GPb in complex with DK12
Descriptor: 5-ethynyl-1-(beta-D-glucopyranosyl)pyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2012-04-10
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.
Eur.J.Med.Chem., 54, 2012
4EKE
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BU of 4eke by Molmil
Crystal structure of GPb in complex with DK11
Descriptor: 3-(beta-D-glucopyranosyl)-6-pentylfuro[2,3-d]pyrimidin-2(3H)-one, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2012-04-09
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.
Eur.J.Med.Chem., 54, 2012
4EKY
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BU of 4eky by Molmil
Crystal structure of GPb in complex with DK15
Descriptor: 1-(beta-D-glucopyranosyl)-5-(pent-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2012-04-10
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.
Eur.J.Med.Chem., 54, 2012
4EL0
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BU of 4el0 by Molmil
Crystal structure of GPb in complex with DK16
Descriptor: 3-(beta-D-glucopyranosyl)-6-propylfuro[2,3-d]pyrimidin-2(3H)-one, Glycogen phosphorylase, muscle form
Authors:Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2012-04-10
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment.
Eur.J.Med.Chem., 54, 2012
5O52
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BU of 5o52 by Molmil
Glycogen Phosphorylase b in complex with 33b
Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ...
Authors:Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2017-05-31
Release date:2017-09-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
J. Med. Chem., 60, 2017
5O50
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BU of 5o50 by Molmil
Glycogen Phosphorylase b in complex with 33a
Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-phenyl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ...
Authors:Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D.
Deposit date:2017-05-31
Release date:2017-09-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
J. Med. Chem., 60, 2017
4YLD
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BU of 4yld by Molmil
The crystal structure of Sclerotium Rolfsii lectin variant 1 (SSR1)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Sclerotium Rolfsii lectin variant 1 (SSR1)
Authors:Kantsadi, A.L, Peppa, V.I, Leonidas, D.D.
Deposit date:2015-03-05
Release date:2015-07-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants.
Molecules, 20, 2015

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PDB entries from 2024-03-27

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